The invention provides a therapeutic system comprising: a console, wherein the console comprises a controller and an energy generator; a therapeutic device comprising: an operational head configured for transmitting the energy output from to a biological tissue; and a memory device comprising control instructions, wherein said control instructions comprise instructions for controlling the console; a reversible memory operable linkage linking the memory device to the controller; and a reversible connector configured for operably linking the energy generator to the operational head.

Optionally, the energy generator is a generator of ablation energy or heat energy (e.g. RF generator) and the control instructions comprise instructions for controlling the output of the energy generator. Optionally, the control instructions comprise one or more parameters of energy output or an algorithm configured for controlling the energy output. Optionally, the system further comprises one or more secondary therapeutic devices and the control instructions comprise instructions for controlling the one or more secondary therapeutic devices. Optionally, the system further comprises one or more sensors configured for sensing parameters of energy output or biological or environmental effects of the energy output and the control instructions comprise instructions for controlling the energy output and/or secondary therapeutic devices based on the parameters of energy output or biological or environmental effects. In some embodiments, one advantage provided by the present invention is the use of a single console with a plurality of interchangeable reversibly connected therapeutic devices.

Provided is a virtual reality (VR) device, system and framework for generating VR continuum experience choreographed to a physical procedure incorporating at least one procedural action associated with a physical sensation and potentially inducing an anxiety or pain response. The VR continuum experience can modify perceptions of pain and anxiety associated with the procedure. The virtual reality device is configured to allow device control via a device user interface accessible to an operator other than the wearer (i.e. a medical practitioner), to allow the operator to control device calibration and virtual reality (VR) experience start while the apparatus is worn by the wearer, and to provide one or more VR experiences each associated with a physical procedure.

Various control methods can indirectly determine incorrect connections between components in a respiratory therapy system. For example, incorrect connections can occur between a patient interface, a humidifier and/or a gases source. The methods can indirectly detect if reverse flow conditions or other error conditions exist. A reverse flow condition can occur when gases flows in a direction different from an intended direction of flow. The methods can be implemented at the humidifier side, at the gases source side, or both.

Systems and methods for generating nitric oxide are disclosed. A nitic oxide (NO) generation system includes at least one pair of electrodes configured to generate a product gas containing NO from a flow of a reactant gas; and a controller configured to regulate the amount of nitric oxide in the product gas produced by the at least one pair of electrodes by utilizing duty cycle values of plasma pulses selected from a plurality of discrete duty cycles to produce a target rate of NO production based on an average of discrete production rates associated with each of the plurality of discrete duty cycles.

A method of monitoring the flow of a gas along a channel, the method including the steps of: Utilising at least a first ultrasonic transducer to project an alternating ultrasonic signal substantially transverse to the direction of gas flow and ultrasonic receivers to receive the signals; Sampling the ultrasonic signal after it traverses the gas flow; and Processing the sampled signal to determine properties of the gas and flow parameters relating thereto.

A method that includes receiving, in a medication delivery module, a command to start a medication delivery from a first control module coupled to the medication delivery module, is provided. The command to start the medication delivery is based on clinical information received at the first control module. The method includes recording, in a memory of the medication delivery module, an update of the medication delivery, receiving an indication that the medication delivery module was decoupled from the first control module, and receiving an indication that the medication delivery module has become coupled with a second control module. The method also includes communicating, in response, with the second control module, to update the clinical information. A system and a non-transitory, computer readable medium storing instructions to perform the above method are also provided.

A medicament delivery device development evaluation system is presented having a dummy medicament delivery device comprising at least one force sensor configured to detect an external force applied to the dummy medicament delivery device, processing circuitry configured to receive force measurements from the force sensor, and a storage medium configured to store the force measurements received by the processing circuitry.

Embodiments of the present invention provide for maintaining a level set of a pulmonary artery catheterization apparatus that includes a pulmonary artery pressure sensor in communication with a pulmonary artery catherization manifold affixed to a pulmonary artery catheter. The method includes calibrating leveling of the pulmonary artery pressure sensor (at the level of the right atrium) with the pulmonary artery catheterization manifold by recording a vertical level of a leveling base positioned at a common level to the manifold, relative to a vertical level of a leveling sensor positioned at a common level to the pulmonary artery pressure sensor. The method further includes monitoring a difference between the recorded vertical level of the leveling base relative to the vertical level of the leveling sensor. Finally, the method includes generating an alert in a user interface element of the leveling sensor in response to the monitored difference exceeding a threshold value.

A method for testing a drug delivery device including a piezoelectric transducer, a microcontroller, and a DC power source, with the piezoelectric transducer having an operative state and inoperative state. The method includes providing a drive signal to the piezoelectric transducer of the drug delivery device, determining an actuation voltage value or an actuation current value, and comparing the actuation voltage value or the actuation current value to a baseline value to determine whether the piezoelectric transducer is in the operative state or the inoperative state.

Ablation catheters and systems include catheter tips with a positioning element to ablate a target tissue that damages substantial cellular component in the target tissue while avoiding significant damage to the extra cellular matrix.