Described herein are devices, systems, and methods for generating a variable liquid vacuum with an accompanying stable gas flow rate. In particular, when a suction device suctions a liquid and gas mixture it is advantageous to provide a variable vacuum or vacuum to apply to the liquid component while the flow rate of the gas stays constant or essentially constant.

A gas guide tube assembly (200), a liquid storage device (10), a humidifier, and a ventilator. The gas guide tube assembly (200) comprises: a gas outlet guiding tube (210) having a gas inlet port (212) and a gas outlet port (214); and a guide tube (220) having a communication port (222) that communicates with the gas inlet port (212) of the gas outlet guiding tube (210) and a plurality of gas reflux ports (224, 226) that communicate with the communication port (222). The gas guide tube assembly (200), when in use, is disposed in a liquid storage cavity (120) of the humidifier, and the gas outlet port (214) of the gas outlet guiding tube (210) of the gas guide tube assembly (200) communicates with a gas outlet (124) of the liquid storage cavity (120). The present invention can solve to a certain extent a problem of water inhalation into the user due to overflow from the gas outlet (124).

A system for performing an endoscopic surgical procedure in a surgical cavity of a patient that includes a gas delivery device configured to deliver a flow of pressurized gas to a gas delivery lumen extending therefrom, a gaseous sealing module communicating with a distal end of the gas delivery lumen and configured to generate a gaseous seal within a gas sealed lumen extending therefrom, and an access port communicating with a distal end of the gas sealed lumen so as to provide sealed instrument access to the surgical cavity and maintain a stable pressure within the surgical cavity.

An artificial lung including a housing having a circular outer wall being enclosed by a first surface and a second surface to define an interior volume, a blood inlet port to permit inlet flow of blood to the housing, a blood outlet port to permit outlet flow of the blood from the housing, a gas inlet port to permit inlet flow of a gas to the housing, a gas outlet port to permit outlet flow of the gas from the housing, and a plurality of baffles concentrically disposed within the housing. The baffles are positioned to define a flow path between the blood inlet port and the blood outlet port. Each of the baffles includes a gate opening to permit flow of the blood along the flow path. A fiber bundle is disposed between the baffles within the flow create mixing and improve gas exchange efficiency.

An integrated kit for separating blood and concentrating PRP includes: (a) a main body that includes an upper storage portion, a lower storage portion, and a passage portion for connecting the upper storage portion and the lower storage portion; (b) a upper cover coupled to an upper end of the upper storage portion; (c) an inner stopper inserted into a lower end of the lower storage portion so as to seal the lower storage portion; (d) a closing adjustment screw which can move vertically while penetrating a hole formed at the inner stopper and seals the passage portion; and (e) a lower cover coupled to an outside of the lower end of the lower storage portion and the outside of the inner stopper to prevent the separation of the closing adjustment screw coupled to the inner stopper in case of centrifugation.

A device for an aspirator, the device comprising a suction inlet for suctioned air, liquid and particles; an exhaust outlet for air; a reservoir for collecting liquid and particles separated from the air; and a clearing arrangement fluidly between the suction inlet and the exhaust outlet, the clearing arrangement being configured to provide a path of air, substantially cleared from liquid sucked through the suction inlet, to the exhaust outlet, in any orientation of the device in space. An aspirator comprising a device, and a method of modifying a device for an aspirator, are also provided.

A small form factor metered dose inhaler is disclosed. The inhaler includes a casing having a longitudinal axis and a transverse axis. The casing has a mouthpiece opening at one end along the longitudinal axis. The casing is configured to house a medicament canister along the longitudinal axis. The medicament canister contains a plurality of doses of a pulmonary medicament and a metered dose valve configured to release a metered dose of the pulmonary medicament through the mouthpiece opening along the longitudinal axis. A mechanical linkage translates an applied input force to the mechanical linkage into an output force along the longitudinal axis configured to actuate the metered dose valve and release the metered dose of the pulmonary medicament in a direction along the longitudinal axis. The aerosolized medicament exits the casing in a fluid flow which is symmetric in a vertical plane along the longitudinal axis.

Flush syringe assemblies capable of creating pulsatile movement of the plunger rod as it moves in the distal direction within a syringe barrel, while preventing overpressurization of the catheter are provided. An exemplary flush syringe assembly includes a syringe barrel with a first pulsing element and a chamber with flush solution, a plunger rod with a stopper and a second pulsing element that interacts with the first pulsing element to provide an engagement force that causes pulsatile movement of the plunger rod and a thumb press slidably attached to the plunger rod with a pulse control element. The pulse control element is compressible to create a compression force that is greater than the engagement force of the first pulsing element and the second pulsing element.

The present invention is directed to an assembly and method of use thereof for reducing microbial load in an airway of a patient. The assembly includes a miniature vacuum unit. The miniature vacuum unit includes a housing, at least one air inlet configured in the housing for air intake; a vacuum motor for sucking the air through the at least one air inlet; vents configured in the housing for blowing the sucked air out of the housing, a filter media covering inner side of the vents, such as the sucked air passes through the filter media, the filter media configured to retain microbes suspended in the sucked air; and at least one suction tube. The suction tube is having a proximal end and a distal end, the proximal end of the at least one suction tube configured to sealably and releasably coupled to the at least one air inlet, a plurality of apertures configured in the wall of the suction tube near its distal end. The suction tube configured to be positioned within the mouth of the patient.

Filtering device for filtering cerebrospinal fluid are disclosed. An example filtering device may include a filter housing having an inlet for receiving cerebrospinal fluid from a patient and an outlet for returning filtered cerebrospinal fluid to the patient. The filter housing may include a plurality of layers coupled together and defining a fluid pathway therein between the inlet and the outlet. A filtering section may be defined within the filter housing along the fluid pathway. The filtering section may include a widened region of the fluid pathway that is configured to slow the passage of fluid therethrough.