An oxygenator having a plurality of porous hollow fiber membranes for gas exchange to treat blood is manufactured by dissolving a silicone compound in an organic solvent having a surface tension of less than 70 dyn/cm to prepare a coating solution, and bringing an inner surface of the hollow fiber membranes into contact with the coating solution under a negative pressure of 50 hPa or more and 150 hPa or less to form a silicone compound-containing coating layer on the inner surface. An antithrombotic polymer compound-containing coat can be provided directly on an outer surface of the hollow fiber membranes.

An assembly nest for transporting a tubular sub assembly of a drug delivery device on an automated production line, in which the tubular sub assembly includes a tubular body and a cap that is wider than the tubular body. The assembly nest includes a base against which a sub assembly of a drug delivery device is mountable to orientate said sub assembly in a predetermined position; and locking mechanism having a resilient member to urge the locking mechanism into one of: an unlocked position, in which a sub assembly of a drug delivery device can be mounted to the base; or a locked position, in which the locking mechanism engages a mounted sub assembly to retain it in its predetermined position on the base.

The invention relates to a method for connecting a first component, in particular a lancing means, to a second component, in particular a syringe body, in order to produce a product for medical or cosmetic purposes, by means of adhesion, having the following steps: (a) providing the first and the second component; (b) tempering at least one first contact surface of the first component and/or at least one second contact surface of the second component to a temperature T1; and (c) applying an adhesive to at least one portion of the first contact surface and/or to at least one portion of the second contact surface, wherein the adhesive is at a temperature T2, wherein temperatures T1 and T2 differ only by a tolerance deviation, wherein the tolerance deviation is at most 10° C.

A tray (100) for accommodating a coiled medical device, such as a catheter assembly (700), includes a first compartment (101), a second compartment (102), and a third compartment (103). The catheter assembly (700) and devices associated with a catheterization procedure, such as syringes (701,702) containing sterile water and lubricating jelly and a specimen container (703) can be disposed within the tray. Printed instructions (1001) can be included with the tray (100). When a CSR wrap (1000) is disposed about the tray (100), the printed instructions can be placed atop the CSR wrap (1000) but beneath an outer sterile wrap (1002). The printed instructions (1001) can include a patient portion (1202) that is detachably coupled to a health care services portion (1201) such that it can be taken home with the patient after the procedure.

A dialyzer housing manufacturing system includes a molding device configured to mold a dialyzer housing, and a tool coupled to a robotic arm and configured to retrieve the dialyzer housing from the molding device after the dialyzer housing is molded. The tool includes a frame, a first suction cup connected to a first portion of the frame, and a second suction cup connected to a second portion of the frame, the second suction cup being oriented about 70 degrees to about 110 degrees relative to the first suction cup.

A patient interface including a seal-forming structure with a textile membrane that has at least one hole such that the flow of air at a therapeutic pressure is delivered to at least an entrance to the patient's nares and/or an entrance to the patient's mouth. The seal-forming structure is constructed and arranged to maintain the therapeutic pressure in a cavity of a plenum chamber throughout the patient's respiratory cycle, in use. The textile membrane includes a first portion that is held in a relaxed state and a second portion that is held in a taut state. The taut state of the second portion is configured to allow the seal-forming structure to include a three-dimensional shape that has multiple curvatures.

An additive manufacturing system may include a heating cartridge defining an interior volume and at least one filament port. The system may include a heating element thermally coupled to the heating cartridge to heat the interior volume. The system may also include a filament handling system to feed at least one filament through the at least one filament port. The system may include a substrate handling system having at least a head stock. The system may include a controller configured to initiate or control movement of a substrate relative to the heating cartridge to apply a jacket to the substrate.

A torque-limiting device comprises a plunger rod holder defining a piston cavity for receiving at least a portion of a plunger rod, a moveable stop element, a dowel disposed adjacent the stop element, a spring disposed adjacent the dowel, and a syringe barrel holder defining a barrel cavity for receiving at least a portion of a syringe barrel.

Apparatus and methods are described for manufacturing a housing for an impeller of a blood pump. A mandrel is placed inside an inner lining, with a central cylindrical portion of a frame disposed around the inner lining, the mandrel being shorter than a length of the inner lining. A portion of an elongate tube is placed around at least a portion of the frame. The inner lining, the frame and the portion of the elongate tube are heated, via the mandrel, and, while heating the inner lining, the frame, and the portion of the elongate tube, pressure is applied from outside the portion of the elongate tube, such as to cause the portion of the elongate tube to become coupled to the frame. Other applications are also described.

Apparatus and methods are described including a ventricular assist device that includes an impeller disposed within a frame and configured to pump blood through a pump-outlet tube and out of one of more blood outlet openings. The frame includes an inner lining. A protective braid is disposed over a distal portion of the frame and configured to block structures from the subject's left ventricle from entering into the frame. A proximal end of the protective braid is embedded between the pump-outlet tube and the inner lining, such that, during crimping of the frame, the braid becomes crimped with the pump-outlet tube and the inner lining, thereby preventing the braid from moving with respect to pump-outlet tube or the inner lining. Other applications are also described.