The present disclosure relates to systems, apparatuses, and methods for assembling cartridges for aerosol delivery devices. The cartridges may be assembled by transporting carriages between various substations at which parts are added to a base. In another assembly method, the base may be moved between a plurality of robots which direct the base downwardly into contact with components to couple the components therewith. An inspection system may inspect the cartridges at various stages of completion.

An apparatus and method are disclosed for a biofunctional molecular imprint medical device configured to remain in permanent or temporary contact with a body comprising a supportive structure, a surface material that receives and retains a molecular imprint and that is positioned to contact a body tissue or other substance during use, a molecular imprint of a bioactive molecule wherein an imprinted cavity is of a bioactive molecule that catalyzes the promotion or suppression biological processes and at least one of a semiconductor, a nanoparticle quantum dot, a nano-island, and a quantum wire, wherein the nanoparticle quantum dot, nano-island, or quantum wire produces an electron wave function configuration that dynamically reconfigures the electron charge distribution within the molecular imprint, enabling tuning of the imprinted cavity.

A catheter includes an elongated shaft extending in a longitudinal direction and possessing an outer surface, the shaft possessing a distal end, a proximal end and a proximal portion which includes the proximal end, a transverse direction being perpendicular to the longitudinal direction, the elongated shaft being an elongated tubular body having a lumen formed therein, and a tubular hub fixed by insert molding to the outer surface of the shaft along the proximal portion of the shaft. The hub possesses a residual stress at one predetermined location of the hub that exceeds the residual stress of the hub at each of: (i) a first position distal to the one predetermined location, (ii) a second position proximal to the one predetermined location, and (iii) a third position being at the one predetermined location in the longitudinal direction and spaced apart from the one predetermined location in the transverse direction.

A system for producing a graft device for a patient may comprise: an imaging device configured to produce image data of a tubular conduit; and a processing unit configured to receive the image data from the imaging device. The processing unit may comprise an algorithm configured to process the image data, and produce a construction signal based on the image data. A material delivery device may be configured to receive the construction signal from the processor, and deliver material to produce a 3D covering based on the construction signal. The graft device may comprise the 3D covering positioned about the tubular conduit. Graft devices and methods of producing graft devices may also be provided.

Hollow fiber membranes in an oxygenator for an extracorporeal blood circulator are coated with an antithrombotic polymeric material. The porous hollow fiber membranes for gas exchange have outer surfaces, inner surfaces forming lumens, opening portions through which the outer surfaces communicate with the inner surfaces in a housing. A blood flow path is outside of the hollow fiber membrane bundle in the housing, between a blood inlet port and a blood outlet port. The coating is obtained by filling the blood flow path with a colloidal solution containing an antithrombotic polymeric compound, and moving the colloid solution between the blood inlet port and the blood outlet port for a time that coats a predetermined amount of antithrombotic polymeric compound on the outer surfaces of the hollow fiber membranes. Other surfaces within the oxygenator contacting the blood flow likewise receive the coating.

A hemostasis valve assembly includes a hollow body delimiting an inner passage for inserting a medical material, the inner passage extending between a proximal opening and a distal opening of the hollow body, a distal seal arranged at the distal opening, a proximal seal arranged at the proximal opening, a spacer element arranged between the distal seal and the proximal seal, and an end cap. The distal seal is an elastic valve that is sealed when idle. The end cap has a fixing element engaging a support element of the hollow body to fix a stacked assembly including the distal seal, the spacer element, and the proximal seal inside the hollow body.

A removal device (121, 221) for removing and disposing of a pen needle (113, 213) connectable to a drug delivery device (111, 211) includes a body (123, 223) having a cavity (141, 241) for receiving the pen needle of the drug delivery device such that a patient end (116, 216) of a needle (115, 215) of the pen needle is covered by the body. An ejector (151, 251) is movably connected to the body (123, 223) for engaging the received pen needle (113, 213) and selectively ejecting the engaged pen needle from the body. The pen needle (113, 213) is securely retained within the removal device (121, 221) without exposing the needle (115, 215) of the pen needle until the pen needle (113, 213) can be properly disposed of, such as in a sharps container, thereby substantially preventing an accidental needle stick.

A vaporizer device for an inhaler, in particular for an electronic cigarette product or a medical inhaler, comprising: a vaporizer film, which in turn comprises a layer system with a polymer film and at least one metal film which contacts the polymer film over its surface and is designed as a heating element a liquid reservoir, and a wick structure, which is configured to supply the vaporizer film with liquid from the liquid reservoir, wherein the vaporizer film comprises at least one first receiving opening for receiving liquid and at least one dispensing opening for dispensing vaporized liquid, wherein the vaporizer film is in contact with the wick structure via the base surface, wherein the vaporizer film forms at least one supply channel, via which the at least one first receiving opening can be supplied with liquid from the wick structure.

The disclosed embodiments include a protective housing for a fragile article for containing fluid medicament. The protective housing includes a shroud top including an upper collar for absorbing one or more forces, a shroud base configured to receive the shroud top and including a lower collar for absorbing one or more forces, a spike configured to pierce the fragile article and coupled to the shroud top or the shroud base, and a connector located at the shroud top or the shroud base, the connector configured to provide the fluid medicament from the fragile article to an injector

Disclosed herein are sterilized medical coiled tubing and process for producing the same. One process comprises: helically winding a length of the medical tubing along a mandrel such that adjacent turns of the medical tubing are in contact with each other; applying solvent where the turns of the medical tubing contact each other to produce coiled medical tubing; allowing the solvent to dry; removing the medical tubing from the mandrel after the solvent has dried; and subjecting the medical tubing to a sterilization process using ethylene oxide with in-chamber aeration.