The present invention provides a disposable bioprocess bag, a manufacturing method therefor and a hot-melt annular welding machine, relating to the technical field of biopharmaceutics. The manufacturing method comprises: preparing a first cropping template to a fourth cropping template according to a top, an upper portion, a lower portion and a bottom of a bioreactor; cropping a raw material film according to the first cropping template to the fourth cropping template to obtain a first membrane material to a fourth membrane material, wherein the fourth membrane material directly serves as a rounded bottom; welding at least two pockets on the first membrane material to obtain a rounded top; welding the second membrane material to obtain a cylindrical upper portion; welding the third membrane material to obtain a lower portion in the shape of an inverted rounded truncated cone; and welding, using a hot-melt annular welding machine, the rounded top, the cylindrical upper part, the lower portion in the shape of an inverted rounded truncated cone and the rounded bottom, to obtain a disposable bioprocess bag. According to the present invention, the physical properties of the welded edge of the disposable bioprocess bag are improved, and the fit of the disposable bioprocess bag to the bioreactor are also enhanced.

An assembly for the automated production of conical paper sleeves for plants uses paper stock precut in a trapezoid configuration which is continuously fed to the assembly. The precut sheets are folded diagonally twice to form a conical sleeve. The folding process includes application of an adhesive on the overlap of the folded sides to securely seal the sleeve. The precut sheets are transported along the assembly via a series of belts, rollers and electrical motors. The synchronization of the folding process and the application of adhesive is electronically monitored and controlled.

A leak proof container and a method of forming the container from a blank. The blank includes a bottom panel, first and second side panels connected to the bottom panel at opposing lateral edges, and first and second end portions located at opposing longitudinal ends of the blank. Each end portion includes an inner end panel connected to the bottom panel, an outer end panel connected to the inner end panel, and first and second corner panels forming gussets connected to a respective one of the first and second side panels and connected to the inner end panel. An adhesive area is located on one side of the blank and comprises at least a portion on each of the outer end panel and the inner end panel. The adhesive area adheres the gussets to the inner end panel and to the outer end panel.

A leak proof container and a method of forming the container from a blank. The blank includes a bottom panel, first and second side panels connected to the bottom panel at opposing lateral edges, and first and second end portions located at opposing longitudinal ends of the blank. Each end portion includes an inner end panel connected to the bottom panel, an outer end panel connected to the inner end panel, and first and second corner panels forming gussets connected to a respective one of the first and second side panels and connected to the inner end panel. An adhesive area is located on one side of the blank and comprises at least a portion on each of the outer end panel and the inner end panel. The adhesive area adheres the gussets to the inner end panel and to the outer end panel.

A packaging machine having several work stations, a transport chain and a chain deflection pulley on which the transport chain is mounted. The transport chain comprises chain clips, each chain clip having an upper part and a lower part, wherein the upper part and/or the lower part may be moveable relative to each other to move the chain clips between an open position and a closed position. The material blank may be introduced into the open chain clips and secured in the closed chain clips to transport the material blank in a direction of transport using the transport chain. A chain opening mechanism may be actively and operably changed between an opening state and a closing state in order to open and close at least one chain clip disposed on a planar oriented section of the transport chain and/or to maintain an already opened chain clip in an open state.

A packaging machine having several work stations, a transport chain and a chain deflection pulley on which the transport chain is mounted. The transport chain comprises chain clips, each chain clip having an upper part and a lower part, wherein the upper part and/or the lower part may be moveable relative to each other to move the chain clips between an open position and a closed position. The material blank may be introduced into the open chain clips and secured in the closed chain clips to transport the material blank in a direction of transport using the transport chain. A chain opening mechanism may be actively and operably changed between an opening state and a closing state in order to open and close at least one chain clip disposed on a planar oriented section of the transport chain and/or to maintain an already opened chain clip in an open state.

A process for making a container includes the step of providing at least one of a slider, sticker, textured surface, pattern, or embossed surface along a folded web of thermoplastic material that comprises a plurality of container templates. The process also includes the step of picking up, with a turner, each container template. The turner includes one or more rotator assemblies that include a rotatable shaft and a bag-contacting surface connected to an end of the rotatable shaft. The bag-contacting surface is configured to engage a top exterior side of each container template. Additionally, the process includes the step of reorienting, with the turner, each container template. The rotatable shaft is configured to horizontally translate and rotate each container template.

A process for making a container includes the step of providing at least one of a slider, sticker, textured surface, pattern, or embossed surface along a folded web of thermoplastic material that comprises a plurality of container templates. The process also includes the step of picking up, with a turner, each container template. The turner includes one or more rotator assemblies that include a rotatable shaft and a bag-contacting surface connected to an end of the rotatable shaft. The bag-contacting surface is configured to engage a top exterior side of each container template. Additionally, the process includes the step of reorienting, with the turner, each container template. The rotatable shaft is configured to horizontally translate and rotate each container template.

A system and process for making a container or pouch that separates the cutting and sealing steps into two distinct steps with a separate step of rotating the container or pouch template 90 degrees relative to a direction of travel between the cutting and sealing steps.

A system and process for making a container or pouch that separates the cutting and sealing steps into two distinct steps with a separate step of rotating the container or pouch template 90 degrees relative to a direction of travel between the cutting and sealing steps.