A container (100) is formed by being folded and sealed on one of a multiplicity of male dies (12) of an apparatus (10). The male die (12) with the container (100) placed thereon is inserted into a female die (120). The female die (120) retains the container (100) while the male die (12) is removed therefrom. Lips (110-112) of the container (100) are sandwiched against the female die (120) while product is pushed thereon to prevent collapse of the container (100). The multiplicity of male dies (12) are relatively moveable by rotating about an axis (20) relative to the female die (120).

A tab system for a folder (10a), and a method of making same is disclosed. The tab is enlarged to carry more information/indicia. The visual indicia space (16a), i.e. the viewable space on the front (32a, 36a) of the folder which allows viewing of the enlarged tab is achieve without violating the overall size restrictions (40a) of the file folder. Instead, the front of the folder adjacent to the tab on the back panel, is cut away (32a,34a) to expose a greater portion of the back panel (14a) and allow an increase in visual indicia space. The remaining portion of the front panel, not adjacent to the tab may also be cut away (34a) to allow other enlarged tab files, with offset tabs, (22d, 21a) to be viewable behind the present file.

A tab system for a folder (10a), and a method of making same is disclosed. The tab is enlarged to carry more information/indicia. The visual indicia space (16a), i.e. the viewable space on the front (32a, 36a) of the folder which allows viewing of the enlarged tab is achieve without violating the overall size restrictions (40a) of the file folder. Instead, the front of the folder adjacent to the tab on the back panel, is cut away (32a,34a) to expose a greater portion of the back panel (14a) and allow an increase in visual indicia space. The remaining portion of the front panel, not adjacent to the tab may also be cut away (34a) to allow other enlarged tab files, with offset tabs, (22d, 21a) to be viewable behind the present file.

The present invention provides a disposable bioprocess bag, a manufacturing method therefor and a hot-melt annular welding machine, relating to the technical field of biopharmaceutics. The manufacturing method comprises: preparing a first cropping template to a fourth cropping template according to a top, an upper portion, a lower portion and a bottom of a bioreactor; cropping a raw material film according to the first cropping template to the fourth cropping template to obtain a first membrane material to a fourth membrane material, wherein the fourth membrane material directly serves as a rounded bottom; welding at least two pockets on the first membrane material to obtain a rounded top; welding the second membrane material to obtain a cylindrical upper portion; welding the third membrane material to obtain a lower portion in the shape of an inverted rounded truncated cone; and welding, using a hot-melt annular welding machine, the rounded top, the cylindrical upper part, the lower portion in the shape of an inverted rounded truncated cone and the rounded bottom, to obtain a disposable bioprocess bag. According to the present invention, the physical properties of the welded edge of the disposable bioprocess bag are improved, and the fit of the disposable bioprocess bag to the bioreactor are also enhanced.

The present invention provides a disposable bioprocess bag, a manufacturing method therefor and a hot-melt annular welding machine, relating to the technical field of biopharmaceutics. The manufacturing method comprises: preparing a first cropping template to a fourth cropping template according to a top, an upper portion, a lower portion and a bottom of a bioreactor; cropping a raw material film according to the first cropping template to the fourth cropping template to obtain a first membrane material to a fourth membrane material, wherein the fourth membrane material directly serves as a rounded bottom; welding at least two pockets on the first membrane material to obtain a rounded top; welding the second membrane material to obtain a cylindrical upper portion; welding the third membrane material to obtain a lower portion in the shape of an inverted rounded truncated cone; and welding, using a hot-melt annular welding machine, the rounded top, the cylindrical upper part, the lower portion in the shape of an inverted rounded truncated cone and the rounded bottom, to obtain a disposable bioprocess bag. According to the present invention, the physical properties of the welded edge of the disposable bioprocess bag are improved, and the fit of the disposable bioprocess bag to the bioreactor are also enhanced.

A bag making apparatus includes a welding device for welding a sheet panel and a strip member in a zone where the sheet panel is intermittently fed by a feed device and a cut device disposed downstream of the welding device to cross-cut the sheet panel and the strip member every intermitted feed cycle. The welding device include a pressure unit for pressurizing the sheet panel and the strip member superposed on each other and a laser unit for irradiating the sheet panel or the strip member with a laser beam at an irradiation position upstream of a pressure position of the pressure unit to melt the sheet panel or the strip member. The pressure unit and the laser unit are configured to be movable together upstream and downstream relative to the sheet panel while maintaining a relative positional relationship between the pressure position and the irradiation position.

A bag making apparatus includes a welding device for welding a sheet panel and a strip member in a zone where the sheet panel is intermittently fed by a feed device and a cut device disposed downstream of the welding device to cross-cut the sheet panel and the strip member every intermitted feed cycle. The welding device include a pressure unit for pressurizing the sheet panel and the strip member superposed on each other and a laser unit for irradiating the sheet panel or the strip member with a laser beam at an irradiation position upstream of a pressure position of the pressure unit to melt the sheet panel or the strip member. The pressure unit and the laser unit are configured to be movable together upstream and downstream relative to the sheet panel while maintaining a relative positional relationship between the pressure position and the irradiation position.

The present invention relates generally to a protective wrap and a protective envelope or pouch made therefrom, as well as the apparatus and process for forming such wraps and envelopes. Water-based heat-expandable adhesives (WBHEA) which include a plurality of heat-expandable microspheres are disposed in a pattern between web substrates on a continuous, high speed manufacturing line to produce padded, insulated products useful as envelopes, mailers and other protective packaging.

The present invention relates generally to a protective wrap and a protective envelope or pouch made therefrom, as well as the apparatus and process for forming such wraps and envelopes. Water-based heat-expandable adhesives (WBHEA) which include a plurality of heat-expandable microspheres are disposed in a pattern between web substrates on a continuous, high speed manufacturing line to produce padded, insulated products useful as envelopes, mailers and other protective packaging.

An apparatus for making a self-opening bag pack includes a supply of flexible film material. An extruder forms a continuous tube of film. A flattener flattens the tube. A first sealer forms a bottom seal across a width of the flattened tube. A cutter cuts the flattened tube into bag blanks has a bag mouth at a predetermined distance from the bottom seal. Second and third sealers form angled seals at lower corners of the bag blank forming a flat bottomed bag. An adhesion knife penetrates the bag pack adhering adjacent bag blanks together in the bag pack. An aperture maker forms apertures for suspending the bag pack from a dispensing rack. The pack is attached to the dispensing rack and the front wall of the subsequent bag is adhered to the rear wall of a first bag, thereby causing the first bag to open when pulled from the rack