A patient interface including a positioning and stabilizing structure that is configured to maintain a first seal-forming structure and a second seal-forming structure in a therapeutically effective position. The positioning and stabilizing structure comprises a frame coupled to the plenum chamber. The frame includes a central portion coupled to the plenum chamber outside of the cavity. The frame also includes a pair of arms that extend away from the central portion in a posterior direction past the second seal-forming structure. The pair of arms are more flexible than the central portion. The positioning and stabilizing structure also includes headgear straps coupled to the frame, which configured to provide a tensile force to the first seal-forming structure and to the second seal-forming structure into the patient's face via the frame.

An improved cartridge for containing an inhalable substance. The cartridge may comprise a wrapping or exterior material having the same or similar combustion properties as the inhalable substance contained within the cartridge. The cartridge may be placed into a vaporizer or similar device where the inhalable substrate is vaporized to generate a gaseous version of the inhalable substance, such as tobacco vapor, marijuana vapor, or atomized medicine without burning of or contamination by the wrapping or exterior material.

An infusion line harness includes a rectangular material with first and second anchor tabs opposing ends of a first longitudinal edge of the rectangular material such as to extend the first longitudinal edge of the material to include a length of the first and second anchor tabs. The rectangular material includes one or more first fasteners positioned on the rectangular material along the first longitudinal edge and one or more complimentary fasteners positioned along the second longitudinal edge and which are configured to connect to the one or more first fasteners, the first fasteners and second fasteners being positioned such that when connected to each other the rectangular material forms a tubular structure. The first and second anchor tabs each are configured to wrap around a respective object and fasten to itself, or to a respective portion of the rectangular material, to anchor the harness to the respective object.

A tray (100) for accommodating a coiled medical device, such as a catheter assembly (700), includes a first compartment (101), a second compartment (102), and a third compartment (103). The catheter assembly (700) and devices associated with a catheterization procedure, such as syringes (701,702) containing sterile water and lubricating jelly and a specimen container (703) can be disposed within the tray. Printed instructions (1001) can be included with the tray (100). One or more layers of wrap material (2200) can be folded about the tray (100) to enclose the tray (100) and other items, such as an additional layer of wrap material (2701), packaged liquid hand sanitizer (2401), and packaged gloves (2402). When a health care services provider (3101) unfolds the wrap material, the same can be used to create a sterile field beneath a patient (3201).

The disclosure provides methods, formulations, and apparatus for making and using cannabinoid formulations.

A method is provided that includes intranasally dispensing nasal wash fluid into a nasal cavity of a subject such that the nasal wash fluid washes biological material into an oropharynx of the subject from (a) the nasal cavity, (b) a nasopharynx of the subject, or (c) the nasal cavity and the nasopharynx. The method further includes, thereafter, collecting a specimen sample that passed out of an anterior opening of an oral cavity of the subject and contains at least a portion of the biological material washed into the oropharynx by the nasal wash fluid. Thereafter, information is derived from extracellular vesicles present in the specimen sample. Other embodiments are also described.

A patient interface for respiratory therapy includes an interface body and a housing for receiving the interface body. The patient interface also includes a securement member having a pair of support pads, each of the support pads configured to engage the face of a user. In some configurations, the interface body can be a cannula body or a mask body. In some configurations, the housing can receive different interface bodies, and the interface bodies are interchangeable.

Introduced here is a self-contained face mask system with an automated liquid-droplet dispensing mechanism (ADM) for humidification. The enclosure of the self-contained mask system can be comprised of one or more layers of breathable fabric adapted to flexibly conform to the face of a user when worn to form a cavity that is adjacent the nostrils and mouth. The ADM of the face mask system can be comprised of a reservoir in which liquid is stored, a respiratory cycle detector, a timer and controller, and a droplet dispenser that controllably dispenses droplets of the liquid from the reservoir into the cavity for inhalation by the user. The ADM can be contained entirely within the face mask enclosure or supported on the surface of the face mask enclosure such that the self-contained mask system, when worn by a user, can be supported entirely by the head and neck of the user.

A positive air pressure delivery device includes a housing having an inhalation inlet, an inhalation outlet, and an interior cavity in fluid communication with the inhalation inlet and outlet. A pressurized fluid inlet includes an outlet orifice in fluid communication with the interior cavity between the inhalation inlet and outlet. A sound reducer baffle has a convex dome surface positioned downstream of and facing the outlet orifice in a spaced apart relationship therewith. One embodiment of the housings includes a body, an end cap and a baffle insert. In various embodiments, the positive air pressure delivery device may be used in combination with other therapy devices, including an OPEP and pressure indicator. A kit and method of using the device are also provided.

A blower unit for use as part of an integrated blower/humidification system is described. The blower unit has an outer casing, which encloses and forms part of the blower unit, the casing including an air inlet vent. The blower unit further includes a humidifier compartment for receiving a humidifier unit with a separate gases inlet and outlet, the compartment having a heater base for heating the contents of the humidifier unit. The compartment also has a blower inlet port which aligns with the humidifier unit inlet in use, the blower providing a gases path through the casing between the inlet vent and the inlet port. The blower unit also includes a fan for providing a pressurised gases stream along the gases path, and a power supply unit for powering the fan. The gases path is routed over the power supply unit in order to provide a cooling air flow.