A device for treating human keratin materials that delivers a cosmetic or dermatological composition onto the latter together with the application of an electric current, in particular an electrophoresis device, the composition applied being contained in a cartridge carried by the device, the cartridge having a body that forms a reservoir and a piston through which a drive screw passes and which can move in the body under the effect of the relative rotation of the screw and the piston, the device comprising an electric drive motor for bringing about this relative rotation of the screw and of the piston, and an electronic circuit for controlling the electric motor.

A needle disk roller apparatus having a built-in pump, includes: a drug container (11) filled with a drug and having a built-in pump assembly (10); and a roller head (14) being able to interwork with the pump assembly (10), supplied with the drug by up-down pressing, configured to form holes in the skin using a plurality of needle disks (21) so that the drug penetrates into the skin, and having a drug base (16) that prevents the drug supplied from the pump assembly (10) from flowing down, and accumulates a predetermined amount of the drug inside an arcuate bottom (28) so that the drug is appropriately supplied to the needle disks 21 when the needle disks 21 are rotated.

Embodiments of an actuating device for actuating a needle cartridge and puncturing an epidermis with controlled depth. The actuating device includes a motor housed in a motor housing, an actuating rod driven by the motor and configured to actuate in a reciprocating motion, and an adjustment mechanism. The actuating rod is housed in a rod housing, the rod housing forming a device aperture configured to receive a needle cartridge and to attach to the needle cartridge. The adjustment mechanism interfaces with the rod housing and is configured to adjust a position of the rod housing relative to the motor housing while not rotating the rod housing relative to the motor housing.

An apparatus for delivering an active ingredient into the skin of an animal at a defined depth, the apparatus including: a microprojection array including a plurality of microprojections having a density of at least 2,000 projections per cm.sup.2; and an applicator that drives the microprojection array towards the skin in use so that the microprojection array impacts on the skin with a mass-to-velocity ratio of between 0.0005 g/m/s and 0.1 g/m/s per cm.sup.2.

The invention is directed to a method for using a polymer composition for connecting a first object to a second object, wherein the method comprises, the step of applying a polymer composition to at least part of the surface of at least one of the first object or second object; connecting the first object and the second object at the surface where the polymer composition is applied and irradiating the polymer composition using UV-radiation over a first time period, obtaining a UV radiated polymer composition; irradiating the UV radiated polymer composition with gamma-radiation over a second time period obtaining a gamma radiated polymer. The invention also relates to a system of a plastic object and a metal object connected by the method of the invention. In addition, the invention relates to a cosmetic method for anti-aging skin treatment wherein the method comprises the steps of: subcutaneously administering of an effective amount a of a dermal filler or Botulinum toxin to an area of skin, preferably the face and/or neck area, wherein the administering is performed by a syringe and a hypodermic needle or cannula of the invention.

Systems, methods and devices for administering medication are disclosed. One or more embodiments of a medication delivery device may include a syringe, a needle, a guiding element, and a volume limiter for limiting the amount of medication that can be drawn from a vial. At least one method for administering medication using a medication delivery device, may include: inserting a vial into a guiding element, drawing back on a plunger, removing the guiding element and the vial from a needle to expose the needle, inserting the needle into a patient, depressing the plunger to inject the medication into the patient, and withdrawing the medication delivery device from the patient.

This application relates to a hand-held cooling device for supplying a cryogen to a target region for cryotherapy. The device can include a cryogen container configured to contain a first cryogen having a first temperature and a nozzle configured to spray a first modified cryogen to the target region, the first modified cryogen having a second temperature higher than the first temperature. The device can also include a cryogen temperature regulator configured to receive the first cryogen and output the first modified cryogen to the nozzle, the cryogen temperature regulator disposed closer to the nozzle than the cryogen container. The cryogen temperature regulator can include a holder tube, a porous structure disposed inside a holder tube and a heater disposed around the holder tube and heating the holder tube so as to increase the first temperature to the second temperature while the first cryogen passes through the porous structure.

The present invention relates generally to devices comprising one or more microstructures that are used to relieve, treat or prevent pain. The devices are designed such that they are inserted into the superficial layers of the skin to achieve pain relief. The devices are designed such that the microstructures are able to grasp and secure to the skin. The devices may consist of microstructures in arrays that are attached to a backing to enable the devices to adhere to the skin. Also provided are wound closure systems that comprise one or more microstructure devices along with other components, such as protective covers and therapeutics. A variety of packaging specifications are disclosed, as is a dispenser apparatus configured to enable simple one-handed application of the devices. Methods described herein provide for treatment of pain.

A kit system has a beginning level kit apparatus, an intermediate level kit apparatus, and an advanced kit apparatus. The beginning level kit apparatus has a first derma roller having a head with a plurality of needles each having a length of five tenths millimeters situated thereon. Additionally, the beginning level kit apparatus has a first chemical compound comprising vitamin A.sub.1 at a first potency. The beginning level kit apparatus also has a first red light therapy device that that is configured to emit red light having a wavelength in the range of six hundred ten nanometers to seven hundred nanometers for a predetermined minimum time period of ten minutes. Finally, the beginning level kit apparatus has a beginning level enclosure apparatus that that encloses the first derma roller, the first chemical compound, and the first red light therapy device.

A non-laser tattoo removal method that includes the steps of cleaning and drying a target area on a user's skin, the target area including at least one tattoo disposed thereon; administering a deracination serum to the target area with a handheld automatic needle assembly having a plurality of needles after the cleaning and drying of the target area; wiping the target area with an absorbent material to remove an extracted pigmented material at least partially composing the tattoo; applying a malleable clay formulation material to cover the target area and leaving the malleable clay formulation material on the target area until forming a dried-on clay formulation; removing the dried-on clay formulation from the target area; and applying a liquid healing agent to the target area after removing the dried-on clay formulation from the target area and covering the liquid healing agent with at least one transdermal drug delivery sheet for selective removal by the user after a healing time period.