A wearable apparatus capable of altering a physiological parameter such as the heart rate of a user to provide a relaxing or stimulating effect on the user is provided. The apparatus comprises a device capable of engaging the patient's skin to provide a rhythmic tactile stimulus to the user that can alter the user's heart rate and an arrangement for securing the device to the user such that the device can apply the stimulus to the user. The apparatus may be part of a system enabling the device to be controlled remotely. The apparatus may also be configured to provide additional tactile stimuli.

The present invention relates to an automated stimulation device for inducing a tactile inter-stimulus onset asynchrony (ISOA) effect in a subject suffering from apnea, bradycardia and/or hypoxia, the device comprising at least two actuators configured for contacting a body portion of the subject, and interspaced for producing an apparent tactile movement in the subject upon sequential induction of actuation, wherein the duration of the actuations and the overlap in actuation time between the at least two actuators is controlled to attain an inter stimulus onset asynchrony (ISOA).

Methods for transdermal delivery of glycosaminoglycans (GAGs) are disclosed, comprising applying ultrasound to the skin followed by topical administration of one or more GAGs optionally complexed with a polysaccharide carrier. When GAG is hyaluronic acid complexed with a modified starch, a transdermal delivery method is provided for facilitating delivery of high molecular weight hyaluronic acid into deep layers of the epidermis and to the dermis in a non-invasive, convenient and painless way. This transdermal delivery method may be applied in treatment of skin aging phenomena associated with collagen and/or hyaluronic acid depletion or loss.

Module for housing electronic and electromechanical medical equipment including a portable digital camera and processing circuitry with machine vision and machine learning software for automatically documenting healthcare events and healthcare equipment operations in the electronic health record.

A system and method for dermal spraying includes a portable, hand-held dermal application device with one or more disposable cartridges that spray a dermal formulation onto the skin, the disposable cartridge having a nozzle that can be activated by placing the cartridge into the spray device.

A system and method for dermal spraying includes a portable, hand-held dermal application device with one or more disposable cartridges that spray a dermal formulation onto the skin, the disposable cartridge having a nozzle that can be activated by placing the cartridge into the spray device.

A needle guard for a manual tattooing device includes a device body and a spring-loaded plunger having a tattoo needle at one end. The plunger is mounted for translational movement within the device body by manual activation of the plunger. The device includes a locking mechanism such that, in a first position, the plunger can be translated to extend the tattoo needle outside of the device body. However, in a second position of the locking device, translational movement of the plunger is prevented, which in turn prevents the exposure of the tattoo needle outside the confines of the device body.

An improved device delivers a fluid medicament to the subcutaneous tissue of a user. The device is better suited for patients with Parkinson's Disease and other central nervous system disorders, than conventional infusion devices. The device can include a reusable part including a drive component (e.g., motor) and control electronics and a disposable part including a medicament reservoir. Medicament can be evacuated from the medicament reservoir by a plunger assembly that includes a plunger attached to a lead screw that is rotated by a nut, all within the disposable part. The device can be fluidically coupled with the tissue via a flexible cannula. Various embodiments relate to an improved cannula insertion mechanism that delivers the cannula under a force applied by a spring. Various embodiments relate to improved filling of the device, for example, using a vial adapter and an automated filling station.

The kit evaluates the patient's skin for penicillin sensitivity. The kit comprises a container, a multi-site skin test system, five preloaded syringes, and a tattoo-type label that is transferable onto the patient's skin. A multi-site skin test applicator is cooperatively engageable with four reservoirs in a fluid tray. The applicator pierces the patient's skin as trace amounts of the allergy test fluids are simultaneously administered. The tattoo-type label is transferable onto the skin of the patient and includes a QR Code. The QR Code includes machine-readable linkage to artificial intelligence for assisting a doctor in interpreting patient test results. The doctor reviews the artificial intelligence analysis and decides either to accept the analysis or modify it. The doctor may also decide to verify negative results with a subcutaneous skin test. The five syringes are preloaded with saline, two syringes are preloaded with Pre-Pen, and two syringes are preloaded with Pen-G.

A method of treatment for mixed carbon dioxide, carbonic acid, saline and optional active additives for treating non-nasal ailments includes delivery of dosage of the treatment at specified flow rates, using a) main housing having a hollow central area containing the dosage; b) a dosage dispenser head located at the distal end of the main housing, and having at least one flow channel for movement of the dosage from the main housing through the dosage dispenser head and to external of the dosage dispenser head; c) a dosage release control component located between the main housing and the dosage dispenser head to permit flow of the dosage through the dosage dispenser head in response to increased pressure against the dosage; and d) a pressure-changing moveable component on the main housing.