A catheter devices/systems and methods therefrom are described herein for treating acute kidney in-jury, especially the contrast-induced acute kidney injury wherein the devices prevent the contrast dyes from entering into kidney and/or facilitate blood flow of kidney by said catheter system.

Vascular treatment and methods include a plurality of self-expanding bulbs and a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Joints between woven structures and hypotubes include solder. Woven structures include patterns of radiopaque filaments measureable under x-ray. Structures are heat treated to include at least shapes at different temperatures. A catheter includes a hypotube including interspersed patterns of longitudinally spaced rows of kerfs. Heat treating systems include a detachable flange. Laser cutting systems include a fluid flow system.

An example syringe includes a barrel having a distal end region and an inner surface defining a lumen extending therein, wherein the inner surface includes a proximally facing surface, and wherein the distal end region includes a distal end. The syringe also includes a plunger having a body portion and a distal tip extending distally away from a distal end region of the body portion, wherein the distal end region includes a distally facing surface. Further, the plunger is configured to be positioned within the lumen of the barrel and a portion of the distal tip of the plunger extends distally of the distal end of the barrel when the plunger is positioned within the lumen of the barrel.

A multi-chamber syringe for delivering a plurality of fluids to a central venous catheter includes a barrel and a plunger. The barrel includes a plurality of chambers, and a first one of the plurality of chambers has a predefined volume of a saline flush stored therein. Actuation of the plunger causes the predefined volume of the saline flush to be dispensed from the barrel into the central venous catheter.

Systems, methods and kits for treating hemorrhages within cavities are provided. The methods utilize the application of a rapid spike of pressure to the closed cavity, followed by a steady state pressure or pressures.

The present disclosure relates to compositions comprising phospholipids, lipid vesicles, and/or liposomes, and methods of use thereof. In one aspect, the present disclosure relates to methods and compositions for delivery of, biologically active lipids to reduce microvascular dysfunction and infarct size during revascularization of the blocked artery in a mammalian subject.

Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, engaging an interventional device of a catheter system with clot material in a blood vessel and withdrawing the interventional device and the portion of the clot material through a guide catheter. In some embodiments, the catheter system can include an attachment/valve member coupled to a proximal portion of the guide catheter, and the method can include unsealing the attachment/valve member to facilitate withdrawing the interventional device through the attachment/valve member without significant retention of clot material within the attachment/valve member. The method can further include resealing and aspirating the guide catheter before advancing another interventional device to the clot material to again engage and remove clot material from the blood vessel.

An injection system is described that receives, from one or more sensors, a first group of one or more signals indicating a current volume of injection fluid dispensed from a fluid reservoir at a first time. The injection system determines, based on the first group of one or more signals, that a difference between a dispensed volume limit and the current volume of the injection fluid dispensed from the fluid reservoir at the first time is less than a necessary volume of fluid required to complete both a systolic injection phase and a diastolic injection phase. The injection system further, responsive to determining that the difference is less than the necessary volume of fluid required to complete both the systolic injection phase and the diastolic injection phase, controls the injection system to refrain from performing each of the systolic injection phase and the diastolic injection phase.

Various catheter systems using a patient's own bodily fluids to increase local fluid velocity and therefore localized lower pressure via the Venturi effect. Exemplary systems utilize a pump to suction and eject blood to/from an attached catheter. One catheter comprises a valve moveable such that the area of the opening at the distal end for fluid passage is larger during suction than during ejection. Another catheter comprises openings in the sidewall and a balloon at the distal end to temporarily occlude the vessel during suction. Another catheter comprises a narrow distal opening and multiple openings with valves in the catheter sidewall. When catheters are deployed near a lymphatic opening into the circulation, such as at the thoracic duct, the ejection of blood from the catheter may cause a localized pressure reduction aiding in the reintroduction of lymph into the circulation.

The described invention provides an endovascular device comprising a tube comprising a first end comprising a bifurcation and a second end comprising an opening. The bifurcation at the first end comprises a first branch and a second branch. The opening at the second end comprises a primary opening and a secondary opening. The first branch and the primary opening form a working lumen. The second branch and the secondary opening form a support lumen. The described invention further provides an endovascular device comprising a tube comprising a side-hole, a first segment comprising a primary opening and a second segment. The side-hole and the first segment form a working lumen. The second segment forms a support lumen.