A method of determining a duration of safe apnoea. Information is obtained relating to a respiratory indicator, which can include information relating to a potential respiratory equilibrium, and a duration of safe apnoea is determined from the obtained information.

Systems and methods for hypoxia delivery are provided. An apparatus for providing intermittent normoxia and hypoxia intervals includes a breathing component, a normoxia fluid source, a hypoxia fluid source, a valve, and a control system. The valve is configured to disrupt flow from at least one of the normoxia fluid source and the hypoxia fluid source and the control system is configured to cause the at least one valve to switch between delivery of fluid from the normoxia fluid source and the hypoxia fluid source while maintaining positive pressure at the breathing component.

Systems and methods for hypoxia delivery are provided. An apparatus for providing intermittent normoxia and hypoxia intervals includes a breathing component, a normoxia fluid source, a hypoxia fluid source, a valve, and a control system. The valve is configured to disrupt flow from at least one of the normoxia fluid source and the hypoxia fluid source and the control system is configured to cause the at least one valve to switch between delivery of fluid from the normoxia fluid source and the hypoxia fluid source while maintaining positive pressure at the breathing component.

A lighting system for establishing a database of multispectral circadian rhythm lighting scenario and psychological stress indicators is configured in space, which is characterized by downloading the multispectral circadian rhythm lighting scenario database from the cloud; the multispectral lighting parameters and circadian rhythm parameters are selected from the multispectral circadian rhythm lighting scenario database to start the light-emitting device for lighting; the ambient light sensor measures and judges whether the circadian rhythm parameters reach the set value; when each circadian rhythm parameter in the circadian rhythm lighting scenario database has reached the set value, the light-emitting device is started for lighting; after the blood or saliva of the light control subjects were tested, the psychological stress index values of the illuminators were obtained; the portable communication device transmits the circadian rhythm parameters and psychological stress index values to the cloud; among them, the circadian rhythm parameters include: circadian rhythm lighting parameters and circadian rhythm scenario parameters.

A lighting system for establishing a database of multispectral circadian rhythm lighting scenario and psychological stress indicators is configured in space, which is characterized by downloading the multispectral circadian rhythm lighting scenario database from the cloud; the multispectral lighting parameters and circadian rhythm parameters are selected from the multispectral circadian rhythm lighting scenario database to start the light-emitting device for lighting; the ambient light sensor measures and judges whether the circadian rhythm parameters reach the set value; when each circadian rhythm parameter in the circadian rhythm lighting scenario database has reached the set value, the light-emitting device is started for lighting; after the blood or saliva of the light control subjects were tested, the psychological stress index values of the illuminators were obtained; the portable communication device transmits the circadian rhythm parameters and psychological stress index values to the cloud; among them, the circadian rhythm parameters include: circadian rhythm lighting parameters and circadian rhythm scenario parameters.

A process and a device determine an indicator of an intrinsic end-expiratory pressure in the lungs of a patient. Embodiments are based on the device, ventilator with the device, and the process using the device that includes an interface arrangement configured for an exchange of information with a ventilation device and a control unit that determines first information on a first breathing pressure generated by muscles of the patient, at a first time, at which an inhalation attempt of the patient is present and determines second information on a second breathing pressure generated by the muscles of the patient, at a second time, at which breathing gas flow towards the patient starts. The control unit further determines the indicator of the intrinsic end-expiratory pressure based on the first information and based on the second information.

A process and a device determine an indicator of an intrinsic end-expiratory pressure in the lungs of a patient. Embodiments are based on the device, ventilator with the device, and the process using the device that includes an interface arrangement configured for an exchange of information with a ventilation device and a control unit that determines first information on a first breathing pressure generated by muscles of the patient, at a first time, at which an inhalation attempt of the patient is present and determines second information on a second breathing pressure generated by the muscles of the patient, at a second time, at which breathing gas flow towards the patient starts. The control unit further determines the indicator of the intrinsic end-expiratory pressure based on the first information and based on the second information.

Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. In an example, CSF is separated into a permeate and retentate using a tangential flow filter. The retentate is filtered again and then returned to the subject with the permeate. During operation of the system, various parameters may be modified, such as flow rate and waste rate.

A sleep training device is disclosed comprising certain electronic components, audio components, light-emitting diodes (LEDs), physical switches, a capacitive touch component, or a combination thereof. The sleep training device can have a housing configured to house the electronic components, the audio components, the LEDs, the capacitive touch component, and at least part of the physical switches. The sleep training device can receive an instruction to schedule a sleep program based on a set parameter from another device in wireless communication with the sleep training device, initiate the sleep program once the set parameter is met, and disable at least one of the physical switches and the capacitive touch component when the sleep program is initiated.

A sleep training device is disclosed comprising certain electronic components, audio components, light-emitting diodes (LEDs), physical switches, a capacitive touch component, or a combination thereof. The sleep training device can have a housing configured to house the electronic components, the audio components, the LEDs, the capacitive touch component, and at least part of the physical switches. The sleep training device can receive an instruction to schedule a sleep program based on a set parameter from another device in wireless communication with the sleep training device, initiate the sleep program once the set parameter is met, and disable at least one of the physical switches and the capacitive touch component when the sleep program is initiated.