In general, systems for administering a dmg are provided. In an exemplary embodiment, a dmg administration system includes a dmg administration device configured to communicate with a computer system and at least one sensor configured to obtain sensor data and communicate the sensor data to the drug administration device. The dmg administration device is configured to utilize a first drug dosing scheme when a drug is delivered to a patient, determine a second drug dosing scheme for delivering a drug to the patient dependent on dosing data from the computer system and sensor data collected by the sensor during and/or after the delivery of the first drug according to the first drug dosing scheme, and utilize the second drug dosing scheme when the drug is delivered to the patient.

In general, systems for administering a dmg are provided. In an exemplary embodiment, a dmg administration system includes a dmg administration device configured to communicate with a computer system and at least one sensor configured to obtain sensor data and communicate the sensor data to the drug administration device. The dmg administration device is configured to utilize a first drug dosing scheme when a drug is delivered to a patient, determine a second drug dosing scheme for delivering a drug to the patient dependent on dosing data from the computer system and sensor data collected by the sensor during and/or after the delivery of the first drug according to the first drug dosing scheme, and utilize the second drug dosing scheme when the drug is delivered to the patient.

Methods and systems for assessing characteristics of a lung of a patient. A method includes, during an applied positive end expiratory pressure, identifying a first position of a patient, acquiring first impedance data representative of at least a region of patient's lung when the patient is in the first position, during the applied positive end expiratory pressure, identifying a second different position of a patient, acquiring second impedance data representative of at least the region of patient's lung when the patient is in the second position, comparing the first impedance data with the second impedance data, and determining whether the applied positive end expiratory pressure is sufficient to effectuate recruitment.

Methods and systems for assessing characteristics of a lung of a patient. A method includes, during an applied positive end expiratory pressure, identifying a first position of a patient, acquiring first impedance data representative of at least a region of patient's lung when the patient is in the first position, during the applied positive end expiratory pressure, identifying a second different position of a patient, acquiring second impedance data representative of at least the region of patient's lung when the patient is in the second position, comparing the first impedance data with the second impedance data, and determining whether the applied positive end expiratory pressure is sufficient to effectuate recruitment.

Methods and apparatus provide controlled operations in an oxygen concentrator (100) such as by adjusting valve opening time to regulate amount of oxygen enriched air released to a user. The apparatus may generate, with a sensor configured to sense pressure at a location associated with accumulation of enriched air produced by the concentrator, a signal representing measured pressure of the accumulated enriched air. The apparatus may generate, with a sensor, a signal indicative of respiration of a user of the concentrator. The apparatus may include a controller configured to receive the measured pressure and respiration signals. The controller may control, responsive to the respiration indication and according to a target duration, actuation of a valve adapted to release a bolus of accumulated oxygen enriched air. The controller may dynamically determine the target duration during the release of the bolus according to a function of a value of the measured pressure.

Methods and apparatus provide controlled operations in an oxygen concentrator (100) such as by adjusting valve opening time to regulate amount of oxygen enriched air released to a user. The apparatus may generate, with a sensor configured to sense pressure at a location associated with accumulation of enriched air produced by the concentrator, a signal representing measured pressure of the accumulated enriched air. The apparatus may generate, with a sensor, a signal indicative of respiration of a user of the concentrator. The apparatus may include a controller configured to receive the measured pressure and respiration signals. The controller may control, responsive to the respiration indication and according to a target duration, actuation of a valve adapted to release a bolus of accumulated oxygen enriched air. The controller may dynamically determine the target duration during the release of the bolus according to a function of a value of the measured pressure.

A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient includes a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the respiratory gas is controlled by a microprocessor, a mixing area for mixing a first gas and a second gas in the respiratory gas flow pathway, a humidification area downstream of the mixing area and configured for humidifying respiratory gas in the respiratory gas flow pathway, and a heated delivery conduit for minimizing condensation of humidified respiratory gas.

A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient includes a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the respiratory gas is controlled by a microprocessor, a mixing area for mixing a first gas and a second gas in the respiratory gas flow pathway, a humidification area downstream of the mixing area and configured for humidifying respiratory gas in the respiratory gas flow pathway, and a heated delivery conduit for minimizing condensation of humidified respiratory gas.

Methods and apparatus for providing circadian-friendly LED light sources are disclosed. A light source is formed to include a first LED emission (e.g., one or more LEDs emitting a first spectrum) and a second LED emission (e.g., one or more LEDs emitting a second spectrum) wherein the first and second LED emissions are combined in a first ratio and in a second ratio such that while changing from the first ratio to the second ratio the relative circadian stimulation is varied while maintaining a color rendering index above 80.

Methods and apparatus for providing circadian-friendly LED light sources are disclosed. A light source is formed to include a first LED emission (e.g., one or more LEDs emitting a first spectrum) and a second LED emission (e.g., one or more LEDs emitting a second spectrum) wherein the first and second LED emissions are combined in a first ratio and in a second ratio such that while changing from the first ratio to the second ratio the relative circadian stimulation is varied while maintaining a color rendering index above 80.