The present disclosure pertains to a system and method for automatically detecting rapid eye movement (REM) sleep and delivering sensory stimulation to prolong REM duration, without disturbing sleep. The sensory stimulation may be auditory or other stimulation. The system and method ensure timely delivery of the stimulation and automatically adjust the amount, intensity, and/or timing of stimulation as necessary. REM sleep is detected based on brain activity, cardiac activity and/or other information. REM sleep may be detected and/or predicted by a trained neural network. The amount, timing, and/or intensity of the sensory stimulation may be determined and/or modulated to enhance REM sleep in a subject based on one or more values of one or more intermediate layers of the neural network and one or more brain activity and/or cardiac activity parameters.

The disclosure provides systems and methods for neuromodulation using a housing that at least partially contains a stimulator assembly, wherein the stimulator assembly is configured to generate vibration by mechanical oscillation and/or using a sound wave; and wherein the vibration generated by the stimulator assembly is configured to therapeutically treat the subject by stimulating one or more nerves when the housing is placed in proximity to or on a skin surface of a subject.

The disclosure provides systems and methods for neuromodulation using a housing that at least partially contains a stimulator assembly, wherein the stimulator assembly is configured to generate vibration by mechanical oscillation and/or using a sound wave; and wherein the vibration generated by the stimulator assembly is configured to therapeutically treat the subject by stimulating one or more nerves when the housing is placed in proximity to or on a skin surface of a subject.

A dialysis treatment system for hemodialysis includes a processor to acquire blood flow information and patient biological information in a blood circuit for hemodialysis, the patient biological information being peripheral vascular resistance information, blood pressure information, face information, body movement information, temperature information, and humidity information and to acquire patient individual difference information from the blood related information; and to perform dialysis treatment for the patients on the basis of the patient individual difference information.

Described is an apparatus for oxygenation and/or CO2 clearance of a patient, comprising: a flow source or a connection for a flow source for providing a gas flow, a gas flow modulator, a controller to control the gas flow, wherein the controller is operable to: receive input relating to heart activity and/or trachea gas flow of the patient, and control the gas flow modulator to provide a varying gas flow with one or more oscillating components with a frequency or frequencies based on the heart activity and/or trachea flow of the patient.

Described is an apparatus for oxygenation and/or CO2 clearance of a patient, comprising: a flow source or a connection for a flow source for providing a gas flow, a gas flow modulator, a controller to control the gas flow, wherein the controller is operable to: receive input relating to heart activity and/or trachea gas flow of the patient, and control the gas flow modulator to provide a varying gas flow with one or more oscillating components with a frequency or frequencies based on the heart activity and/or trachea flow of the patient.

A robot-connected IoT-based sleep-caring system includes a sleep-caring robot and an IoT system. The sleep-caring robot includes environment monitoring, physiology monitoring, sleep monitoring, sound, lighting and electricity control, a smart storage compartment, central data processing, and machine arms. The IoT system senses and executes instructions from the sleep-caring robot, thereby catering to bedroom activities of the user.

A robot-connected IoT-based sleep-caring system includes a sleep-caring robot and an IoT system. The sleep-caring robot includes environment monitoring, physiology monitoring, sleep monitoring, sound, lighting and electricity control, a smart storage compartment, central data processing, and machine arms. The IoT system senses and executes instructions from the sleep-caring robot, thereby catering to bedroom activities of the user.

A method of dialysis is provided that includes sensing the concentration of potassium in a patient's blood serum, in used dialysate resulting from treating the patient, or in both. The method involves generating a sensed value of the concentration of potassium, comparing the sensed value with one or more values stored in a memory, and generating a control signal based on the comparison. Supplemental potassium solution is infused into the treatment dialysate, based on the control signal. The comparison can be made to patient-historical data, population data, or both.

A respiratory therapy system can have a flow generator adapted to provide gases to a patient. A gas passageway can be located in-line with the flow generator. The gas passageway can have a first portion adapted to receive a first gas and a second portion adapted to receive a second gas. The gas passageway can have a static mixer downstream of the first and second portions.