Systems and methods for managing heart failure are described. The system receives physiological information including a first HS signal corresponding to paced ventricular contractions and a second HS signal corresponding to intrinsic ventricular contractions. The system detects worsening heart failure (WHF) using the received physiological information. A signal analyzer circuit can generate a paced HS metric from the first HS signal and a sensed HS metric from the second HS signal, and determine a concordance indicator between the paced and the sensed HS metrics. In response to the detected WHF, the system can use the concordance indicator to generate a therapy adjustment indicator for adjusting electrostimulation therapy, or a worsening cardiac contractility indicator indicating the detected WHF is attributed to degrading myocardial contractility.

Sleep performance systems and methods of using the same are disclosed. The sleep performance systems can improve the quality of sleep by making one or more recommendations to the subject for increasing a sleep quality score. The sleep performance systems can have one or more electroencephalography (EEG) electrodes configured to measure a subject's brain activity during sleep. The sleep performance systems can have a processor configured to quantify the quality of the subject's slow-wave sleep by determining one or more sleep performance scores associated with the measured brain activity. The sleep performance systems can recommend and/or activate sleep improvement programs based on various threshold scores.

A system to manage the sleep and/or the well-being of a passenger/user of an aircraft includes a chair to be installed in a cabin of the aircraft and interaction devices to interact with the user. The system further includes a user terminal configured to receive data relating to characteristics of a user profile of the user, and a control/command module connected to the user terminal, interaction devices and a database storing information relating to characteristics of a flight of the aircraft. The command/control module being configured to pilot the interaction devices according to the data relating to characteristics of the user profile and characteristics of the flight of the aircraft.

A system to manage the sleep and/or the well-being of a passenger/user of an aircraft includes a chair to be installed in a cabin of the aircraft and interaction devices to interact with the user. The system further includes a user terminal configured to receive data relating to characteristics of a user profile of the user, and a control/command module connected to the user terminal, interaction devices and a database storing information relating to characteristics of a flight of the aircraft. The command/control module being configured to pilot the interaction devices according to the data relating to characteristics of the user profile and characteristics of the flight of the aircraft.

There is provided herein a stress reducing and/or mindfulness inducing apparatus including: a substantially spherically shaped body “huggable” by two hands of a user; at least a first and a second pair of indentations located on an outer surface of said body, wherein each of the first and the second pair of indentations is suitable for placing corresponding index, middle and ring fingers from each hand of the user, wherein each of the first and the second pair of indentations comprises one or more sensors, wherein the one or more sensors are configured to sense one or more parameters associated with the user's stress and/or mindfulness state, wherein the sensors are the same or different from each other; and an indicator having at least two modes of operation, the indicator is configured to provide the user with an indication regarding his/her stress and/or mindfulness state.

There is provided herein a stress reducing and/or mindfulness inducing apparatus including: a substantially spherically shaped body “huggable” by two hands of a user; at least a first and a second pair of indentations located on an outer surface of said body, wherein each of the first and the second pair of indentations is suitable for placing corresponding index, middle and ring fingers from each hand of the user, wherein each of the first and the second pair of indentations comprises one or more sensors, wherein the one or more sensors are configured to sense one or more parameters associated with the user's stress and/or mindfulness state, wherein the sensors are the same or different from each other; and an indicator having at least two modes of operation, the indicator is configured to provide the user with an indication regarding his/her stress and/or mindfulness state.

Provided is an extracorporeal circulator capable of judging a timing suitable for detachment with high accuracy. The extracorporeal circulator includes a blood removal side catheter with a part that can be inserted into a patient and guide the blood taken from the patient; a pump that can take the blood from the patient and return the blood to the patient; a blood transfer side catheter provided downstream of the pump, and that has a part that can be inserted into the patient and guide the blood sent out from the pump back into the patient; a pump rotation speed detection unit that can detect a rotation speed of the pump; and a control system including at least one of an extracorporeal circulation management system that can judge stability of the extracorporeal circulation and a cardiac function measurement system that can judge stability of a heart function of the patient.

Systems and methods for treating a medical condition such as worsening heart failure (WHF) are described. A medical system may sense one or more physiological signals, and generate from the sensed physiological signals a signal metric trend indicating a progression of heart failure. A detector may detect a physiological event leading to WHF. A therapy control circuit may generate a therapy titration protocol using the generated signal metric trend. The therapy titration protocol includes a temporal profile of therapy dosage relative to a target dosage. The therapy control circuit may adjust the target dosage based on patient response. Therapies may be administered by a clinician or automatically delivered to the patient according to the therapy titration protocol.

Transdermal electrical stimulation (TES) applicators that are wearable and configured to attached to a subject's pinna (ear) and adapted to apply TES to modulate the subject's cognitive and/or physiological state. These apparatuses may be configured so that they can be worn against the ear (e.g., the cymba of the ear) to deliver TES. Also described herein are methods of using them to modulate a subject's cognitive state. These TES applicators may also be adapted to function as audio headphones for concurrent delivery of TES and audible signals (e.g., music).

Disclosed are a massage device providing a tinnitus treatment program and a control method therefor. According to an embodiment of the present disclosure, disclosed is a method by which a massage device provides a tinnitus treatment program. The method by which the massage device provides the tinnitus treatment program comprises the steps of: obtaining tinnitus information about a user; adjusting the magnitude of at least some of a plurality of frequency components included in a raw sound source and then flattening the raw sound source, so as to generate a first processed sound source; reducing the magnitude of at least some of a plurality of frequency components included in the first processed sound source on the basis of the obtained tinnitus information, so as to generate a tinnitus treatment sound source; and providing a tinnitus treatment program in which the generated tinnitus treatment sound source and tinnitus treatment massage are combined.