A drug delivery and monitoring device comprising a nerve stimulating element configured to deliver an electric stimulus, a recording element configured to detect a compound action potential, and a drug-delivery element.

A system for monitoring patient intake includes an acquisition and transmission device having an electrode configured to detect vagus nerve activity. A first internal inductive coil is configured to communicate a signal indicative of the vagus nerve activity detected by the electrode to a second external inductive coil. The system also includes a processor configured to execute instructions stored in a memory that cause the system to process the signal received by the second induction coil into data corresponding to intake of the patient and communicate the data to a server that is accessible by a clinician.

This system for identifying information represented by biological signals is configured so as to detect biological signals (S501), analyze the detected biological signals and then output feature data (S502), determine the respective similarities between the feature data and a plurality of teaching data (S503), store the similarities per time in a time series (S504), and determine information represented by the biological signals on the basis of the plurality of similarities within a prescribed period among the stored similarities in the time series (S505).

Disclosed are methods and medical device systems for automated delivery of therapies for pain and determination of need for and safety of treatment. In one embodiment, such a medical device system may comprise a sensor configured to sense at least one body signal from a patient; and a medical device configured to receive a first sensed body signal from the sensor; determine a patient pain index based at least in part on said first sensed body signal; determine whether said patient pain index is above at least a first pain index threshold; determine a safety index based at least in part on a second sensed body signal; select a pain treatment regimen based on at least one of said safety index and or a determination that said pain index is above said first pain index threshold; and deliver said pain treatment regimen.

A method for treatment of a brain and/or spinal cord includes inserting a flexible catheter into a cerebrospinal fluid space, the flexible catheter including two lumens adapted to allow a fluid to circulate therein in a closed loop within the flexible catheter and the flexible catheter being adapted to be connected to a device for cooling and circulating the fluid. The cerebrospinal fluid in the cerebrospinal fluid space is cooled with the flexible catheter to enable selective central nervous system cooling. The functional status of the brain and/or spinal cord is monitored, and the treatment of the brain and/or spinal cord is modified to adjust for any change in the functional status of the brain and/or spinal cord.

An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive electrodes are formed on the endotracheal tube. The conductive electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least wireless sensor is formed on the endotracheal tube, and is configured to wirelessly transmit information to a processing apparatus.

The present invention relates to the titration and delivery of anesthetic and sedative medications to a subject. Further, the present invention relates to a device and methods for titrating and delivering such medications in a semi-automated or fully automated manner and which can be monitoring and controlled remotely. Even still further, the present invention relates to such a device that can perform the titration and delivery of medication in a manner that minimalizes occlusion and prevents back flow of the medication. More particularly, the present invention relates to a device for titration and delivery of medication using a non-concentric pumping mechanism that gradual or progressively increases and decreases occlusion in the medication delivery line within the pump to minimize and/or prevent sudden formation and release of occlusion in order to provide more steady and continuous flow of the medication through the device to the subject.

The present invention relates to the titration and delivery of anesthetic and sedative medications to a subject. Further, the present invention relates to a device and methods for titrating and delivering such medications in a semi-automated or fully automated manner and which can be monitoring and controlled remotely. Even still further, the present invention relates to such a device that can perform the titration and delivery of medication in a manner that minimalizes occlusion and prevents back flow of the medication. More particularly, the present invention relates to a device for titration and delivery of medication using a non-concentric pumping mechanism that gradual or progressively increases and decreases occlusion in the medication delivery line within the pump to minimize and/or prevent sudden formation and release of occlusion in order to provide more steady and continuous flow of the medication through the device to the subject.

Provided herein is a needle device for a nerve block, which includes a gripping part having a longitudinal passage through which a liquid fluid flows, said liquid fluid also flowing through the inside of a needle aligned with the longitudinal passage. The device also includes a nerve stimulator through which electricity is transmitted to the needle. The gripping part includes a radial duct that intersects tangentially with the longitudinal passage, the radial duct having two opposite female couplings into either of which the nerve stimulator can be inserted, depending on whether the user is left-handed or right-handed.

An improved modular, multi-modal neurostimulation system, includes signal generating, conditioning, and control electronics, stimulation monitoring electronics, and wearable, magnetically coupled energy emitter modules configured for coupling energy emitters to the ear for transcutaneous energy delivery to cranial nerves neurologically accessible in the auricular nerve field. Three energy modalities are available via electrodes for electrical stimulation; optical emitters for electromagnetic stimulation; vibrational emitters for vibrational stimulation. Energy modalities are selectable singularly or in combination. Stimulation control electronics may be integrated within an ear-worn coupling body or located in an external computerized device. Integrated bodily status and biofeedback sensors work with a programmable algorithm to enable closed loop operation based on monitored biofeedback activity, bodily activity and indicia of autonomic functioning. A method for optimizing stimulation using cardiorespiratory feedback and monitoring of divisional indicia of autonomic nervous system function is discussed. Disclosed is a method for optimizing therapeutic interventions via neurostimulation and a method for self-administered neurostimulation and training users in self-administered neurostimulation. Also disclosed is a stimulation coupling apparatus comprising a contour conforming plastic composition for coupling stimulation energy emitters to the auricle of a human being.