An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface and a first location configured to be positioned at the patient's vocal folds. A first electrode is formed on the exterior surface of the endotracheal tube substantially below the first location to receive EMG signals primarily from below the vocal folds. A second electrode is formed on the exterior surface of the endotracheal tube substantially above the first location to receive EMG signals primarily from above the vocal folds. The first and second electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient.

A drug delivery and monitoring device comprising a nerve stimulating element configured to deliver an electric stimulus, a recording element configured to detect a compound action potential, and a drug-delivery element.

An electronic device includes a user interface; a wireless communication circuit configured to communicate with an external electronic device; a processor; and a memory electrically connected to the processor. The memory stores instructions that, when executed by the processor, cause the processor to: identify a user input to start a meditation program via the user interface; start the meditation program in response to the identified user input; receive data related to a stress level of a user measured by the external electronic device during execution of the meditation program from the external electronic device via the wireless communication circuit; and display visual information on the user interface, wherein the visual information visually indicates a stress level change of the user resulting from the execution of the meditation program, based on at least a portion of the received data. In addition, various embodiments identified herein are realized.

An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive electrodes are formed on the endotracheal tube. The conductive electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least wireless sensor is formed on the endotracheal tube, and is configured to wirelessly transmit information to a processing apparatus.

A nerve cuff for establishing a nerve block on a nerve can have a cuff body with a channel for receiving a nerve, a reservoir for holding a drug, and an elongate opening slit extending the length of the cuff body that can be opened to provide access to the channel and can be closed to enclose the cuff body around the nerve. The nerve cuff can also include an electrode for detecting and measuring electrical signals generated by the nerve. A controller can be used to control delivery of the drug based on the electrical signals generated by the nerve.

Presented herein are techniques for clinical-based automated control of the delivery of treatment substances to at least one inner ear of a recipient of an implantable medical device. More specifically, in-vivo biomarkers are analyzed to determine a biological state/status of one or more physiological elements of the inner ear. Subsequent delivery of one or more treatment substances to the inner ear of the recipient are controlled based on the determined biological state of the one or more physiological elements of the inner ear.

A respiratory assistance system can provide high flow therapy to patients. The respiratory assistance system can include a patient interface that can deliver a gas flow to a patient and a gas source that can drive the gas flow towards the patient interface at an operating flow rate. The system can include a controller for controlling the operating flow rate of the gas. The controller can apply multiple test flow rate values in a range as the operating flow rate. For each of the test flow rate values, the controller can measure a patient parameter. The controller can determine a new flow rate value based on the measured patient parameters. Patient parameters can include respiration rate, work of breathing, or any other parameters related to the respiratory circuit.

Systems and methods for measuring signals representative of muscle activity are provided. One method includes detecting an ECG signal through a plurality of electrodes. The ECG signal includes a plurality of ECG sample signals, and each ECG sample signal is a bipolar signal associated with two of the plurality of electrodes and includes a cardiac signal component and a myographic signal component. The method further includes filtering each of the ECG sample signals to remove at least a portion of the cardiac signal component and generate a combined myographic power signal for the two of the plurality of electrodes with which the ECG sample signal is associated. Each combined myographic power signal represents a myographic potential between the two electrodes. The method further includes calculating individual myographic power signals for each of the plurality of electrodes by applying the combined myographic power signals within a covariance matrix.

Systems and methods of assisting a subject to reach a target state include obtaining input of the target state of the subject; and generating a transcutaneous vibratory output to be applied to a portion of a body of the subject to assist the subject in achieving the target state, the transcutaneous vibratory output having variable parameters comprising a perceived pitch, a perceived beat, and a perceived intensity wherein the step of generating the transcutaneous vibratory output further comprises the step of modifying the variable parameters to correspond to the target state.

Systems and methods to mitigate negative effects of a drug in a treatment of a mental health condition include administering a drug to a subject in a therapy session; determining effects of the drug, the effects being counterproductive to the therapy session; and providing tactile stimulation to a subject with a stimulation device that generates transcutaneous vibratory output to be applied to a portion of a body of the subject during the therapy session, wherein the transcutaneous vibratory output is selected to reduce the counterproductive effects of the drug.