The present invention provides systems, methods, and articles for stress reduction and sleep promotion. A stress reduction and sleep promotion system includes at least one remote device, at least one body sensor, and at least one remote server. In other embodiments, the stress reduction and sleep promotion system includes machine learning.

The present invention provides systems, methods, and articles for stress reduction and sleep promotion. A stress reduction and sleep promotion system includes at least one remote device, at least one body sensor, and at least one remote server. In other embodiments, the stress reduction and sleep promotion system includes machine learning.

Implantable devices for drug delivery in response to detected biometric parameters associated with an opioid drug overdose and associated systems and methods are disclosed herein. An implantable drug delivery device configured in accordance with some embodiments of the present technology can include a housing and a reservoir configured to contain a drug for treatment of the opioid overdose. The implantable drug delivery device can also include one or more sensors each configured to detect the biometric parameters associated with the overdose. The implantable drug delivery device can further include a controller configured to receive signals related to the biometric parameter, determine whether the overdose occurred based on the signals, and, if the overdose is detected, cause the drug to be delivered to the patient.

Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.

The present disclosure pertains to a system and method for providing sensory stimulation (e.g., tones and/or other sensory stimulation) during sleep. The delivery of the sensory stimulation is timed based on a combination of output from a trained time dependent sleep stage model and output from minimally obtrusive sleep monitoring devices (e.g. actigraphy devices, radar devices, video actigraphy devices, an under mattress sensor, etc.). The present disclosure describes determining whether a user is in deep sleep based on this information and delivering sensory stimulation responsive to the user being in deep sleep. In some embodiments, the system comprises one or more sensory stimulators, one or more hardware processors, and/or other components.

The present disclosure pertains to a system and method for providing sensory stimulation (e.g., tones and/or other sensory stimulation) during sleep. The delivery of the sensory stimulation is timed based on a combination of output from a trained time dependent sleep stage model and output from minimally obtrusive sleep monitoring devices (e.g. actigraphy devices, radar devices, video actigraphy devices, an under mattress sensor, etc.). The present disclosure describes determining whether a user is in deep sleep based on this information and delivering sensory stimulation responsive to the user being in deep sleep. In some embodiments, the system comprises one or more sensory stimulators, one or more hardware processors, and/or other components.

Negative pressure therapy systems are provided for increasing urine production, the negative pressure therapy system including: (a) a pump assembly, the pump assembly including: (i) a pump configured to provide negative pressure to a kidney, and (ii) a controller configured to regulate the negative pressure provided by the pump within a pressure range that facilitates increased urine production from the kidney.

A system and method for operating an analgesia administration system is disclosed. A control device is associated with a drug delivery device and configured to receive a first user input including at least a portion of a fingerprint of a patient, together with a second user input corresponding to a request to administer medication. The portion of the fingerprint is compared with previously-stored fingerprints to determine an identity of the patient and, in response to receiving the second user input and determining that the patient is an authorized user, one or more sensors are used to obtain one or more signals indicative of a state of the patient. If the state of the patient satisfies a set of medication delivery criteria, the drug delivery device is caused to administer a predefined amount of medication to the patient.

A monitoring device operates to monitor regional citrate anticoagulation (RCA) in a blood treatment system which is configured to administrate citrate to an extracorporeal blood circuit (10) upstream of a dialyzer (11) during a treatment session. At consecutive time steps during the treatment session, the monitoring device obtains a current measurement value of systemic ionized calcium (iCa.sub.SYS) or systemic total calcium (Ca.sub.SYS), operates a predefined algorithm on the current measurement value to generate a current computation value that represents ionized calcium (iCa.sub.2, iCa.sub.3) in blood at a selected location (loc2, loc3) downstream or upstream of the dialyzer (11) in the extracorporeal blood circuit (10), and presents and/or evaluates the current computation value for assessment of the regional citrate anticoagulation. The need for conventional blood sampling and blood analysis upstream and/or downstream of the dialyzer, e.g. during CRRT, is thereby reduced significantly.

A system performs a method for characterizing passage of a patient fluid through a conduit. The method includes quantifying flow of fluidic content through a conduit, where the fluidic content includes a patient fluid, estimating a concentration of a fluid component of the patient fluid in the fluidic content, and characterizing passage of the patient fluid loss through the conduit based on the quantified flow and the concentration of the fluid component. At least one of the quantified flow or the concentration of the fluid component is based on sensor data from a sensor arrangement coupled to the conduit. Other apparatus and methods are also described.