An injection syringe for injecting a first injectable product into a body injection site of an individual, includes a first barrel containing a first product, a first syringe barrel containing the first injectable product, a first plunger displaceably mounted in the first syringe barrel; a hollow needle to be inserted into the body injection site; an adapter connected to the first syringe barrel and the needle, and a verification device to ensure that, when the first injectable product is injected, the hollow needle is not introduced into a blood vessel. The verification device includes a second syringe barrel containing a second product and connected to the adapter and a second plunger displaceably mounted in the second syringe barrel to cause a depression at the distal end of the hollow needle.

Dialysis patients may be affected by renal failure and may be affected by other health conditions, such as hypertension. During and between dialysis sessions, it may be advantageous to monitor various characteristics of the patient and of the dialysis system. As such, a system and method for dialysis biomarker monitoring is provided.

The invention comprises an apparatus and a method for operating a cardiac assist pump, comprising the steps of: (1) providing a cardiac monitor comprising: a cardiac output sensor including an activity sensor and at least two of: a pulse oximeter; an electrocardiogram meter; and a blood pressure monitor; (2) receiving time-varying cardiovascular input data, from the cardiac output sensor, related to a transient hemodynamic state of a cardiovascular system; (3) receiving and operating on time-varying activity input data, from the activity sensor, to generate cardiovascular state information; (4) sensing activity with the activity sensor to generate a target cardiovascular state; (5) repeating both the steps of receiving and operating to update the transient cardiovascular state information and the step of sensing to update the target cardiovascular state; and (6) directing the cardiac assist pump to adjust assisted blood flow, yielding the updated transient cardiovascular state, toward the target cardiovascular state.

Systems, catheters, and methods for accessing and treating along the central nervous system are disclosed. An example method may manage inflammation of the patient to treat a condition of the patient by processing values related to one or more physiological parameters of a patent, identifying when an inflammation condition of the patient has reached a treatment condition based on the processed values, and automatically providing an indication that the inflammation condition has reached the treatment condition. An example indication may include actuation of a treatment protocol. The example method may be performed with an inflammation management system.

A method for sleep monitoring is provided, including: detecting whether a sleep assistance command is received; lighting up a breathing light at a preset frequency in response to receiving the sleep assistance command; monitoring physical sign information of a user in response to receiving a monitoring command; detecting whether the user enters into a sleep state according to the physical sign information; gradually reducing a brightness of the breathing light within a first preset duration until the breathing light is extinguished in a case where the user enters into the sleep state, and determining sleep quality information of the user according to the physical sign information of the user. The physical sign information includes at least breathing information, which is determined according to at least one of: oronasal airflow information, thoracoabdominal motion information, or pressure sensing information.

Systems and methods for adjusting a user's circadian rhythm are described. In some embodiments, a system may include one or more input modules for collecting data, a light source, a processor system including one or more processors that controls the light source, and a memory system storing one or more machine instructions. The system may be configured to obtain light sensitivity data for a user, compare the user's light sensitivity data against calibration data, and based on at least the light sensitivity data and the calibration data, generate instructions for activating the light source to adjust the user's circadian rhythm.

Systems and methods for adjusting a user's circadian rhythm are described. In some embodiments, a system may include one or more input modules for collecting data, a light source, a processor system including one or more processors that controls the light source, and a memory system storing one or more machine instructions. The system may be configured to obtain light sensitivity data for a user, compare the user's light sensitivity data against calibration data, and based on at least the light sensitivity data and the calibration data, generate instructions for activating the light source to adjust the user's circadian rhythm.

A lighting system with a multispectral circadian rhythm lighting scenario, which performs lighting by the following procedures, the procedures include: downloading the multispectral circadian rhythm lighting scenario database from a portable communication device to the cloud through the Internet; the portable communication device selects a multispectral lighting parameter and a circadian rhythm parameter from the multispectral circadian rhythm lighting scenario database to start the light-emitting device to control the illuminator to perform lighting; after the blood or saliva test of the light control subjects, the psychological stress index values of the illuminator were obtained; the portable communication device or the management control module transmits the circadian rhythm parameters and psychological stress index values to the cloud.

A lighting system with a multispectral circadian rhythm lighting scenario, which performs lighting by the following procedures, the procedures include: downloading the multispectral circadian rhythm lighting scenario database from a portable communication device to the cloud through the Internet; the portable communication device selects a multispectral lighting parameter and a circadian rhythm parameter from the multispectral circadian rhythm lighting scenario database to start the light-emitting device to control the illuminator to perform lighting; after the blood or saliva test of the light control subjects, the psychological stress index values of the illuminator were obtained; the portable communication device or the management control module transmits the circadian rhythm parameters and psychological stress index values to the cloud.

Infusion devices and methods are provided for a drug delivery system and can include an infusion needle (1) having a tip end (2) and a drive unit (D) coupled to the infusion needle and arranged for advancing the tip end of the infusion needle to penetrate any fibrosis when the infusion device is implanted in a patient's body. The infusion needle and drive unit are designed for implantation in a patient's body. Other components of the drug delivery system may be part of the implantable infusion device or, alternatively, be for extracorporal use cooperating with the implanted infusion device. Preferably, the infusion needle can be advanced and retracted with each infusion cycle. Furthermore, upon each advancement and/or retraction, the needle may be moved laterally so as to vary the injection site. Needle (1) and drive unit (D) are preferably disposed within a body (15), with the infusion needle being arranged for penetrating a self-sealing penetration membrane (18).