Method for authenticating at least one ventilator with at least one remote station, wherein the ventilator can connect itself via at least one interface to the remote station, at least one authentication file is stored on the ventilator, the authentication file contains at least one signature code of a signing authority, and a public keycode of the signing authority is known to the remote station, the ventilator sends the authentication file to the remote station when establishing the connection to the remote station, the remote station checks the signature code of the authentication file using the public keycode as to whether the signature code originates from the signing point and the ventilator is authenticated when the remote station recognizes the signature code as originating from the signing authority.

Method for authenticating at least one ventilator with at least one remote station, wherein the ventilator can connect itself via at least one interface to the remote station, at least one authentication file is stored on the ventilator, the authentication file contains at least one signature code of a signing authority, and a public keycode of the signing authority is known to the remote station, the ventilator sends the authentication file to the remote station when establishing the connection to the remote station, the remote station checks the signature code of the authentication file using the public keycode as to whether the signature code originates from the signing point and the ventilator is authenticated when the remote station recognizes the signature code as originating from the signing authority.

The embodiments of the present disclosure provide a portable oxygen concentrator. The portable oxygen concentrator may comprise an input configured to receive air flow, a column comprising a housing, an outer porous tube, an inner porous tube, and an inner cavity, and an output configured to release oxygen to a user. The inner porous tube comprises an adsorbent bed comprising a plurality of zeolites, and the column is configured to channel air radially through and across the outer porous tube, through and across the adsorbent bed in the inner porous tube, into the inner cavity of the column, and through the output. When the air flow contacts the adsorbent bed, oxygen is released.

Systems and methods for adjusting a user's circadian rhythm are provided. In some embodiments, a system may be configured to obtain information relating to the user's present circadian rhythm and information relating to one or more anticipated times of sleep and/or wakefulness. The system may generate a model for estimating the user's circadian rhythm. The system may also generate a model for estimating the user's homeostatic sleep drive. Based on one or both models, the system may generate instructions for activating the light source to adjust the user's circadian rhythm.

Systems and methods for adjusting a user's circadian rhythm are provided. In some embodiments, a system may be configured to obtain information relating to the user's present circadian rhythm and information relating to one or more anticipated times of sleep and/or wakefulness. The system may generate a model for estimating the user's circadian rhythm. The system may also generate a model for estimating the user's homeostatic sleep drive. Based on one or both models, the system may generate instructions for activating the light source to adjust the user's circadian rhythm.

A fluid sensor device can include a housing having an inlet and an outlet. The housing can have a fluid reservoir, a sensing assembly, a plunger, a valve, and a plurality of channels. The fluid sensor module can be used to sense constituents in a sample fluid (e.g. patient's blood or dialysate) during a treatment process, such as kidney dialysis procedures. The fluid sensor module can be connected in-line to a medical device to sense the sample fluid.

Systems and methods are provided for combining predictive analytics with a cutting-edge electrochemical sensor having specialized coatings designed to reduce biofouling to (1) monitor drug concentration data of a patient in real-time; and (2) predict future pharmacokinetic parameters for the patient more accurately than existing technologies. Embodiments may construct highly accurate and patient-specific pharmacokinetic models which can dynamically adjust predictions of future pharmacokinetic parameters as they receive real-time drug concentration data from the electrochemical sensor. Certain embodiments may automatically adjust administration of a drug to a patient based on the aforementioned predictions and pharmacokinetic models. Other embodiments may provide a notification to a clinician containing, e.g., a recommended course of drug administration before a patient is woken up.

A method and apparatus for thyroid hormone control using a synthetic module containing thyroid hormone and an intelligent valve control device. In embodiments, the invention consists of an iterative process with three steps. First, blood is measured to detect thyroid hormone concentration. Second, the measured concentration is compared to a target thyroid hormone concentration. Third, the intelligent valve control device optimizes thyroid hormone delivery, correcting for differences between the measured concentration and the target concentration.

Release of a neurological drug in a targeted region of a subject's brain by a drug delivery system (DDS) is intentionally caused by the subject watching or interacting with an audio/video-based task on an electronic display. The DDS is calibrated to release the neurological drug based on a particular pH, lactate level, blood flow, temperature, magnetic field, specific molecules released by brain cells, or other physiological factors within the target region. The interactive task produces the physiological factors in the brain in specific areas of pathology for which the drug is prescribed, and limits drug delivery at areas unaffected by illness where it could disrupt normal function, causing problematic side effects and preventing dose levels optimal for target impact. Feedback from the interactive task and associated cognitive probes also can adapt the interactive task or suggest new pharmacologic agents as the degree or primary focus of brain pathology changes during the course of treatment.

Stress management apparatus includes a wearable device having one or more physiological sensors operable to be engaged with a body of a user. One or more processors communicatively coupled with the wearable device having a memory storing instructions when executed operable to: detect one or more physiological indicators of stress; suggest a stress intervention to the user; monitor compliance with the stress intervention; and track a reduction of the one or more physiological indicators of stress.