Disclosed herein are systems and methods for increasing performance, improving sleep and improving relaxation that involve specifically coordinating nerve stimulation of a cranial nerve (e.g. vagus nerve) in conjunction with augmented reality (AR). According to certain embodiments disclosed are systems that include an AR component that presents information or a stimulus and provides cranial nerve fiber stimulation (CNFS) at strategic times to reduce anxiety/arousal/related during user activity or scenarios and reinforce learning.

Disclosed herein are systems and methods for increasing performance, improving sleep and improving relaxation that involve specifically coordinating nerve stimulation of a cranial nerve (e.g. vagus nerve) in conjunction with augmented reality (AR). According to certain embodiments disclosed are systems that include an AR component that presents information or a stimulus and provides cranial nerve fiber stimulation (CNFS) at strategic times to reduce anxiety/arousal/related during user activity or scenarios and reinforce learning.

Systems, devices, and techniques are disclosed for administering and tracking medicine to patients and providing health management capabilities for patients and caregivers. In some aspects, a method includes receiving one or more analyte values associated with a health condition of the patient user; receiving contextual data associated with the patient user obtained by the mobile computing device, where the obtained contextual data includes information associated with a meal; determining a medicine metric value associated with an amount of medicine active in the body of the patient user; autonomously calculating a dose of the medicine without input from the user based at least on the one or more analyte values, the medicine metric value, and the information associated with a meal; and continuously displaying the calculated dose of the medicine.

A blood pressure prediction method and an electronic device using the same are provided. The method includes the following steps. A training data set is collected. A first blood pressure prediction model is established according to the training data set. Hemodialysis parameter data of a target patient is received, wherein the hemodialysis parameter data includes a first hemodialysis parameter at a previous time point and a second hemodialysis parameter at a current time point. A hemodialysis parameter variation amount between the first hemodialysis parameter and the second hemodialysis parameter is calculated. The hemodialysis parameter variation amount is provided to the first blood pressure prediction model to generate a prediction blood pressure variation associated with a next time point. An operation is performed according to the prediction blood pressure variation of the target patient.

The inventive concepts disclosed and claimed herein are generally directed to an improved assisted walking device, such as a cane, walker or wheelchair, that includes an integrated oxygen concentrator housed within the assisted walking device. In some embodiments, for example, the improved assisted walking device includes a handle, a control pad, an elongated housing having an interior chamber, an oxygen concentrator, a leg member and a foot member. The oxygen concentrator detachably positioned within the interior chamber of the elongated housing and including an adsorption system configured to generate a flow of oxygen enriched gas, a compressor that includes a motor, a battery, a plurality of sieve beds configured to extract oxygen-enriched gas from ambient air, and a controller in communication with the control pad.

Disclosed are methods and medical device systems for automated delivery of therapies for pain and determination of need for and safety of treatment. In one embodiment, such a medical device system may comprise a sensor configured to sense at least one body signal from a patient; and a medical device configured to receive a first sensed body signal from the sensor; determine a patient pain index based at least in part on said first sensed body signal; determine whether said patient pain index is above at least a first pain index threshold; determine a safety index based at least in part on a second sensed body signal; select a pain treatment regimen based on at least one of said safety index and or a determination that said pain index is above said first pain index threshold; and deliver said pain treatment regimen.

This disclosure pertains to a system configured to control light exposure for circadian phase management and/or light deficient disorders of a subject. The system comprises a user interface, physiological sensors configured to generate output signals conveying physiological data of the subject, and a light control valve configured to block or reduce blue light ambient radiation reaching eyes of the subject. Processors are in communication with the user interface, the physiological sensors, the light control valve, and radiation generators. The processors cause the system to receive physiological goals of the subject, determine a light control plan based on the physiological goals, the physiological data, environmental data, and time data. The system operates the light control valve to block or reduce blue light ambient radiation based on the light control plan, and generate, using the one or more radiation generators, therapeutic light radiation based on the light control plan.

Some embodiments disclosed herein relate to medical connectors with a housing comprising a proximal body member and a base member that form an internal cavity with a proximal abutment surface. An elastomeric seal without a guide member is positioned within the internal cavity. A rigid, hollow elongated portion is located within the internal cavity such that in an open configuration, a tip of the elongated portion is more proximal than a proximal surface of the elastomeric seal. A distal portion of the elastomeric seal is seated radially within a region surrounded by a plurality of longitudinally extending protrusions.

Methods, pharmaceutical formulations and devices for the preventative treatment of incidental opioid overdose comprising the intramuscular or subcutaneous administration using an auto-injection device of a pharmaceutical formulation containing the opioid antagonist nalmefene as a prophylactic measure.

A virtual reality and augmented reality system configured for meditation applications including a headset comprising an adjustable strap and a display. The headset further includes heating and cooling elements to provide an immersive virtual reality environment to a wearer. The virtual reality system is operable to determine the physiological condition of the wearer and adjust the virtual reality environment based on the physiological condition of the wearer.