A positive exhalation pressure device increases the pressure gradient in the airways, thereby increasing oxygen saturation levels and decreasing the severity of hypoxia. Various embodiments of the device may be inserted into the nasal and/or oral cavities, or configured as mask devices covering the nasal and/or oral cavities. In some embodiments, the resistance of the device may be varied.

A plurality of flow rate values associated with pressurized air directed to an airway of a user of a respiratory therapy system is received. A plurality of pressure values associated with the pressurized air directed to the airway of the user is received. A first time associated with a first breath of the user and a second time associated with a second breath of the user are identified. The plurality of flow rate values is filtered based at least in part on the identified first time and the identified second time. The filtering produces a subset of the plurality of flow rate values. An intentional leak characteristic curve for the respiratory therapy system is determined using at least two of the subset of the plurality of flow rate values and the corresponding pressure values for said at least two of the subset of the plurality of flow rate values.

A method of controlling a medical device is disclosed for delivering respiratory therapy to a user to treat sleep-disordered breathing, for instance obstructive sleep apnea, Cheyne-Stokes respiration etc. by estimating the user's CO2 percentage or concentration from a dynamic lung model driven by an observed respiration signal. The estimated user's CO2 percentage or concentration can be used to predict breathing events, such as hypopnea and apnea. The predictive capacity can be used for adjusting the respiratory therapy as required or for applying a ramp cycle therapy, in an attempt to reduce the prevalence and adverse effects of the breathing events. In other examples a variable ventilation therapy is provided in which pressure is supplied between first and second pressures, with the pressure being increased over more than one breath, and then dropped relatively rapidly, for example during expiration of a single breath.

A method of controlling a medical device is disclosed for delivering respiratory therapy to a user to treat sleep-disordered breathing, for instance obstructive sleep apnea, Cheyne-Stokes respiration etc. by estimating the user's CO2 percentage or concentration from a dynamic lung model driven by an observed respiration signal. The estimated user's CO2 percentage or concentration can be used to predict breathing events, such as hypopnea and apnea. The predictive capacity can be used for adjusting the respiratory therapy as required or for applying a ramp cycle therapy, in an attempt to reduce the prevalence and adverse effects of the breathing events. In other examples a variable ventilation therapy is provided in which pressure is supplied between first and second pressures, with the pressure being increased over more than one breath, and then dropped relatively rapidly, for example during expiration of a single breath.

An autonomic nerve control device includes an obtainer that obtains a physiological quantity of a user before the user occupies a moving body, and a controller that controls the autonomic nerves of the user occupying the moving body based on the physiological quantity of the user obtained by the obtainer.

A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient, the system including a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the pressurized respiratory gas is controlled by a microprocessor.

A system and method for providing a context-based light and/or auditory stimulus experience to a user that includes administering dosages of light is disclosed. Environmental contextual data and/or personal (e.g., biometric and/or non-biometric) contextual data of a subject are obtained. Specific dosages of light are delivered to a subject based on the obtained environmental and/or personal contextual data. The dosages may be defined according to various parameters, including light wavelength, pulse frequency, intensity, area within the subject's field of vision, duration, pulse waveform shape, or a combination thereof. Auditory stimulus may also be provided, in synchronization with the administered dosages of light, and may be based on the obtained environmental and/or personal contextual data.

Systems and methods for Endovascular Perfusion Augmentation for Critical Care (EPACC) are provided. The system may include a catheter having an expandable aortic blood flow regulation device disposed on the distal end of the catheter for placement within an aorta of a patient. The system may also include a catheter controller unit that causes the expandable aortic blood flow regulation device to expand and contract to restrict blood flow through the aorta. The system may also include one or more sensors for measuring physiological information indicative of blood flow through the aorta, and a non-transitory computer readable media having instructions stored thereon, wherein the instructions, when executed by a processor coupled to the one or more sensors, cause the processor to compare the measured physiological information with a target physiological range associated with blood flow through the aorta such that the catheter controller unit automatically adjusts expansion and contraction of the expandable aortic blood flow regulation device to adjust an amount of blood flow through the aorta if the measured physiological information falls outside the target physiological range.

The present invention relates to an integrated system for monitoring physiological variables in cardiopulmonary bypass process, which utilizes a transducer specifically intended to act directly on the cardiopulmonary bypass. Said system according to the present invention comprises at least two components, one is a CPB transducer and a minimonitor, coupled to each other by means of a cable and an electrical connector.

A hydrogen-containing gas supply system includes one or more hydrogen-containing gas suppliers, one or more acquirers, and a controller. The one or more hydrogen-containing gas suppliers supply a hydrogen-containing gas to one or more areas in a building. The one or more acquirers acquire information indicating that a person is present in the one or more areas. When it is determined that a person is present in a certain area of the one or more areas in accordance with the information acquired by the acquirers, the controller causes at least one of the one or more hydrogen-containing gas suppliers to supply the hydrogen-containing gas to the certain area.