A method of transplanting a sleep state of a first subject (donor) to a second subject (recipient) comprising: capturing a sleep state of the first subject represented by brain activity patterns; and transplanting the sleep state of the first subject in the second subject by inducing the brain activity patterns in the second subject.

A method of transplanting a sleep state of a first subject (donor) to a second subject (recipient) comprising: capturing a sleep state of the first subject represented by brain activity patterns; and transplanting the sleep state of the first subject in the second subject by inducing the brain activity patterns in the second subject.

A pressurized flow of breathable gas is delivered to the airway of a subject in accordance with a therapy regimen. The therapy regimen calls for maintenance of an average tidal volume. The therapy ensures that the subject breaths at a therapeutic breath rate. The breath rate may be determined dynamically based on breathing of the subject early on in a therapy session and/or based on a detected wakefulness of the subject. Inspiration for spontaneous and non-spontaneous breaths may be supported at different levels. The therapy regimen further maintains a beneficial positive end expiratory pressure, to reduce respiratory obstructions and/or for other purposes.

Apparatuses (including devices, kits, and systems) and methods to non-invasively and chemically (rather than thermally) activate thermoreceptors to modulate sleep. For example, described herein are apparatuses including topical compositions that stimulate thermoreceptors on the subject's skin (e.g., forehead, hands, and/or feet) for a period of time to induce a sensation of temperature (heat or cold) without significantly altering the person's actual skin temperature to improve sleep quality, including reducing sleep-onset latency, enhancing depth of sleep, and/or extending the amount of time a subject sleeps. The subject may be suffering from insomnia or some other sleep disorder.

Apparatuses (including devices, kits, and systems) and methods to non-invasively and chemically (rather than thermally) activate thermoreceptors to modulate sleep. For example, described herein are apparatuses including topical compositions that stimulate thermoreceptors on the subject's skin (e.g., forehead, hands, and/or feet) for a period of time to induce a sensation of temperature (heat or cold) without significantly altering the person's actual skin temperature to improve sleep quality, including reducing sleep-onset latency, enhancing depth of sleep, and/or extending the amount of time a subject sleeps. The subject may be suffering from insomnia or some other sleep disorder.

The present invention provides a customized sleep management method performed by a customized sleep management system including a step of collecting a bio-signal by using a computing device; a step of generating user sleep data by performing a pre-processing process on the collected bio-signal; a step of classifying sleep steps by using a sleep analysis model receiving the user sleep data and detecting sleep disorder appearing in the classified sleep steps; and a step of providing customized stimulation for alleviating the detected sleep disorder. The bio-signal includes at least one of an electrophysiological signal and a non-electrophysiological signal.

One or more EMG sensors are configured to sense surface-EMG data indicative of muscle movement of the patient; and transmit surface-EMG data. A controller can identify at least one parameter of the surface-EMG data; compare the parameter to a corresponding dystonia-threshold-value; responsive to a determination that the parameter is greater than the corresponding dystonia-threshold-value: issue a visual-engagement command to a visual unit; and issue a tactile-engagement command to a tactile unit.

One or more EMG sensors are configured to sense surface-EMG data indicative of muscle movement of the patient; and transmit surface-EMG data. A controller can identify at least one parameter of the surface-EMG data; compare the parameter to a corresponding dystonia-threshold-value; responsive to a determination that the parameter is greater than the corresponding dystonia-threshold-value: issue a visual-engagement command to a visual unit; and issue a tactile-engagement command to a tactile unit.

The present disclosure provides a system for processing biological signals. The system may comprise a sensing module comprising one or more sensors for detecting at least one of a biological parameter of a subject and one or more biological signals of the subject, and an additional sensor for detecting ambient conditions associated with a surrounding environment of the subject. The system may comprise a signal processing module in communication with the sensing module, wherein the processing module is configured to aggregate and process data obtained using the one or more sensors to compute one or more markers for the subject. The system may comprise an output device optimization module in communication with the signal processing module and one or more output devices, wherein the output device optimization module is configured to control the output devices using the one or more computed markers and data obtained using the additional sensor.

A device provides a first data signal that indicates an activity of at least one muscle of a patient that is relevant for an inspiratory breathing effort and a second data signal that indicates an activity of at least one muscle of the patient that is relevant for an expiratory breathing effort. The data signals are generated from electromyography (EMG) signals detected by surface electromyography sensors. A computer is configured to determine breathing phase information on the basis of a breathing signal and to check at least one of the electromyography signals or at least one of the separated signals for detectability of a heart signal component and further to assign the signals to an inspiratory breathing activity as well as to an expiratory breathing activity of the patient as a function of the breathing phase information.