Disclosed herein are systems and methods for increasing performance, improving sleep and improving relaxation that involve specifically coordinating nerve stimulation of a cranial nerve (e.g. vagus nerve) in conjunction with augmented reality (AR). According to certain embodiments disclosed are systems that include an AR component that presents information or a stimulus and provides cranial nerve fiber stimulation (CNFS) at strategic times to reduce anxiety/arousal/related during user activity or scenarios and reinforce learning.

Devices, systems, and methods for monitoring respiration using surface temperature, humidity, air pressure, carbon dioxide gas sensors, pulse oximetry sensors and electromyography sensors, and/or acceleration sensors to obtain information related to respiration rate (RR), exhalation/inhalation strength, exhalation/inhalation volume, exhalation/inhalation acceleration, and/or exhalation/inhalation regularity.

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents (TA) within the GI tract and in particular to an antrum wall (AW). Particular embodiments provide a swallowable device (SD) such as a capsule for delivering drugs or other TA into the AW. The SD may contain a pressure sensitive component or assembly which triggers release and insertion of a therapeutic agent preparation (TAP) comprising at least one TA into the AW in response to external pressure, such as pressure applied to the swallowable capsule or other SD by antrum contractions. Particular embodiments of the SD may be shaped so that they self-align within an antrum to properly orient before injection of the TAP into the AW. Embodiments of the invention are particularly useful for orally delivering drugs or other TAs which are degraded within the GI tract and require parenteral injection.

A mechanical ventilator is provided that includes a dashboard display identifying a patient's current ventilatory status within a global or universal ventilatory mechanics map. This dashboard display is dynamically updated with the patient's condition, and shows trends in the patient's ventilation over time. The map identifies suggested safe and unsafe regions of ventilation for the patient, and the ventilator can display informational texts, trigger auditory and/or visual alarms, and transmit alarm communications in response to determining that the patient is approaching or has entered an unsafe region.

Aspects of the present disclosure provide methods, apparatuses, and systems for closed-loop sleep protection and/or sleep regulation. According to an aspect, sleep disturbing noises are predicted and a biosignal parameter is measured to dynamically mask predicted disturbing environmental noises in the sleeping environment with active attenuation. Environmental noises in a sleeping environment of a subject are detected, input, or predicted based on historical data of the sleeping environment collected over a period of time. The biosignal parameter is used to determine sleep physiology of a subject. Based on the environmental noises in the sleeping environment and the determined sleep physiology, the noises are predicted to be disturbing or non-disturbing noises. For predicted disturbing noises, one or more actions are taken to regulate sleep and avoid sleep disruption by using sound masking prior to or concurrently with the occurrence of the predicted disturbing noises.

Aspects of the present disclosure provide methods, apparatuses, and systems for closed-loop sleep protection and/or sleep regulation. According to an aspect, sleep disturbing noises are predicted and a biosignal parameter is measured to dynamically mask predicted disturbing environmental noises in the sleeping environment with active attenuation. Environmental noises in a sleeping environment of a subject are detected, input, or predicted based on historical data of the sleeping environment collected over a period of time. The biosignal parameter is used to determine sleep physiology of a subject. Based on the environmental noises in the sleeping environment and the determined sleep physiology, the noises are predicted to be disturbing or non-disturbing noises. For predicted disturbing noises, one or more actions are taken to regulate sleep and avoid sleep disruption by using sound masking prior to or concurrently with the occurrence of the predicted disturbing noises.

An audio system adapted to provide an auditory stimulation for inducing neural oscillations in a user during sleep.

A method includes applying, via a respiratory therapy system, initial therapy settings for a user during a first sleep session in which the user uses the respiratory therapy system. First physiological data, which is received from one or more sensors, is generated during the first sleep session. Modified therapy settings are applied, via the respiratory therapy system, during a second sleep session of the user. Second physiological data is received from the one or more sensors. The second physiological data is generated by the one or more sensors during the second sleep session. A set of sleep-related parameters is determined based on changes between the first physiological data and the second physiological data. One or more of a recommended therapy or recommended therapy settings is determined based on the set of sleep-related parameters.

A controller or processor(s) implements detection of respiratory related conditions that may serve as control logic to synchronize pressure treatment delivery with a patient's respiratory cycle. Based on data derived from sensor signals associated with the respiratory treatment, a monitoring device, detector or respiratory treatment apparatus may evaluate flow measures from a flow sensor and distinguish flow attributable to the respiratory treatment apparatus and flow attributable to patient respiratory muscles. The determination may serve as a basis of synchronization criteria that controls pressure levels from a pressure treatment apparatus, such as by evaluating the determined patient generated flow or a relationship between total flow and apparatus flow. In some embodiments, data for the cycling conditions is determined in preliminary treatment cycles during which synchronized pressure changes are controlled according to other cycling criteria. The new cycling conditions are then automatically initiated for control of synchronization in subsequent cycles.

A sensor including electrodes, a control module and a physical layer module. The electrodes are configured to (i) attach to a patient, and (ii) receive a first electromyographic signal from the patient. The control module is connected to the electrodes. The control module is configured to (i) detect the first electromyographic signal, and (ii) generate a first voltage signal. The physical layer module is configured to: receive a payload request from a console interface module or a nerve integrity monitoring device; and based on the payload request, (i) upconvert the first voltage signal to a first radio frequency signal, and (ii) wirelessly transmit the first radio frequency signal from the sensor to the console interface module or the nerve integrity monitoring device.