A device and method for forming NO-containing gas flow to treat a biological object is disclosed. The device may include an anode, a cathode, an interelectrode area between the cathode and the anode, an NO-containing gas flow outlet channel leading from the interelectrode area to a nozzle for directing and releasing the NO-containing gas flow from the device and a mechanism to adjust a relative position between the anode and the cathode to produce varying concentrations of NO. In addition, the device may include one or more features for interconnecting the various components to ensure proper and consistent assembly of the device.

A portable device for the decontamination of a breast. The aim of the device is to reduce the risk of mastitis, even when the patient has a medicament incompatibility. For this purpose, the invention includes a decontamination unit which decontaminates the breast at least by means of a physical method.

A portable device for the decontamination of a breast. The aim of the device is to reduce the risk of mastitis, even when the patient has a medicament incompatibility. For this purpose, the invention includes a decontamination unit which decontaminates the breast at least by means of a physical method.

Systems and methods for reducing pathogens near an implant are discussed. In some cases, the methods include reducing contaminants in a portion of a patient that has an implant and that is disposed interior to a closed surface of skin of the patient. The method can further include placing a conduit in the closed surface of skin and flowing an antimicrobial fluid into that portion of the patient to contact the antimicrobial fluid with a surface of the implant and tissue adjacent to the implant. In some cases, the antimicrobial fluid is then removed from the portion of the patient having the implant. As part of this method, biofilm near the implant can be mechanically, ultrasonically, electrically, chemically, enzymatically, or otherwise disrupted. Other implementations are described.

A skin microbiota modulation device that includes a cold plasma assembly configured to generate a cold plasma stimulus including a partially ionized gas mixture and to interrogate a biological surface with the cold plasma stimulus; and a microbiota seeding assembly including one or more target species of micobiota, the microbiota seeding assembly configured to deliver the one or more target species of micobiota to the biological surface.

A skin microbiota modulation device that includes a cold plasma assembly configured to generate a cold plasma stimulus including a partially ionized gas mixture and to interrogate a biological surface with the cold plasma stimulus; and a microbiota seeding assembly including one or more target species of micobiota, the microbiota seeding assembly configured to deliver the one or more target species of micobiota to the biological surface.

A floating type plasma electrode pad includes the plasma electrode made of a conductive metal thin film, a flexible dielectric thin film layered on the plasma electrode, and made of a polymer material, the dielectric thin film being spaced apart from the skin by a predetermined distance such that microdischarge is generated in a space defined between the dielectric thin film and the skin, and a spacer layered on the dielectric thin film, to space the dielectric film from the skin by the predetermined distance.

A floating type plasma electrode pad includes the plasma electrode made of a conductive metal thin film, a flexible dielectric thin film layered on the plasma electrode, and made of a polymer material, the dielectric thin film being spaced apart from the skin by a predetermined distance such that microdischarge is generated in a space defined between the dielectric thin film and the skin, and a spacer layered on the dielectric thin film, to space the dielectric film from the skin by the predetermined distance.

Devices and methods for contactless delivery to a tissue of a subject using applied pulsed electric fields. The methods for controlling a therapy provided to a skin tissue of a subject using applied pulsed electric fields. The methods includes an jetting-nozzle assembly configured to not in directly contact with a skin tissue of a subject to deliver a series of electric field pulses to the skin tissue and a user input configured to receive an operational instruction for the series of electric field pulses. The operational instruction defines at least one of a pulse duration, a pulse frequency, a pulse number, and a pulse amplitude. The methods also includes at least one processor configured to access the operational instruction received by the user input and, using the operational instruction, create an electric field profile to be generated by the jetting-nozzle assembly about the skin tissue of the subject to control a cosmetic skin treatment.

Devices and methods for contactless delivery to a tissue of a subject using applied pulsed electric fields. The methods for controlling a therapy provided to a skin tissue of a subject using applied pulsed electric fields. The methods includes an jetting-nozzle assembly configured to not in directly contact with a skin tissue of a subject to deliver a series of electric field pulses to the skin tissue and a user input configured to receive an operational instruction for the series of electric field pulses. The operational instruction defines at least one of a pulse duration, a pulse frequency, a pulse number, and a pulse amplitude. The methods also includes at least one processor configured to access the operational instruction received by the user input and, using the operational instruction, create an electric field profile to be generated by the jetting-nozzle assembly about the skin tissue of the subject to control a cosmetic skin treatment.