The invention relates to a system for electrical and/or magnetic neuronal stimulation, comprising a signal generator for generating a stimulation signal, in particular an alternating-current stimulation signal, an applicator for applying the stimulation signal, in particular in an area on or directly around the optic nerve, a lead for deriving a measurement signal, in particular an EEG signal, a biomarker calculation unit for calculating a biomarker based on the measurement signal, and an optimization unit, in particular for performing a stochastic optimization process, for optimizing the value of the biomarker by varying the stimulation signal.

A device for providing a magnetic treatment by evoking muscle contraction by a time-varying magnetic field and providing a RF treatment by heating biological structure. The device includes an applicator having an RF electrode and a magnetic field generating device. The device may also include a main unit, a human machine interface, and a control unit. The control unit adjusts a signal provided to the RF electrode and controls an RF circuit, and also adjusts the signal provided to the magnetic field generating device and controls a magnetic circuit electrically insulated from the RF circuit. The RF circuit may include a power source and a power amplifier, and the magnetic circuit may include an energy storage device to supply the magnetic field generating device with electric current.

Methods, system and reagents to treat cancer using magnetic particle are disclosed. The method comprises giving patient magnetic particle in combination with TLR agonist type composition and optionally later followed by immune check point inhibitor treatment at therapeutical effective amount. The magnetic particle and TLR agonist type composition is given by intratumoural injection.

In the treatment of a tumor (126) with radiation therapy (122) is enhanced by a weak magnetic field (130), the field strength time sequence of exposure and shape and contour of the magnetic field are varied to achieve desired results. In one separate aspect, exposure to a magnetic field (130) is continued after exposure to a free radical-creating therapy is ceased or diminished, thereby increasing the lifetimes of free radicals that have already been created. In another preferred embodiment a magnetic field (13) is strategically placed to avoid extending the lives of free radicals in tissue through which a free radical-creating beam must pass, to reach a tumor. This application discloses quantitative parameters for field strength and exposure time to create concentrations and reactivity of free radicals, including long-lived free radicals and discloses the use of shaped, contoured, and designed electromagnetic fields. A treatment planning station (200) is also disclosed.

Apparatus and methods for simultaneously providing an infra-red laser beam and a concentrated uni-polar, pulsed electromagnetic field to a region of interest in the body of a patient are disclosed. The apparatus produces the infrared laser beam from a laser diode and the pulsed electromagnetic field from an electrically conductive coil. The infra-red laser beam and the pulsed electromagnetic field are produced concurrently along a common axis. A focusing magnet is provided to concentrate the lines of flux so that they extend along the laser beam. The apparatus includes a body of Mu-metal shielding surrounding the components of the apparatus except for one pole of the coil from which the lines of flux of the electromagnetic field extend to further concentrate the field and render it effectively uni-polar.

Provided herein are compositions including biocompatible magnetizeable nanoparticles. The nanoparticles have a diameter (average diameter) from about 10 to about 300 nanometers and are biocompatible and magnetic. The nanoparticles may be a disc formed from iron oxide. The disc may be conjugated to a target-binding moiety capable of binding a target. The target may be cancer cells, pathogens, fat cells, or atherosclerotic plaques.

An apparatus includes a torus-shaped mount and a coil including a conducting wire wound around the mount such that the coil has an inductance. The coil is configured to generate electromagnetic fields based on the inductance when electrical signals pass through the coil. The electromagnetic fields have frequencies in an Extremely Low Frequency (ELF) range and a Very Low Frequency (VLF) range. The electromagnetic fields provide therapy to a user. A clip is affixed to the mount and encases terminal ends of the wire. The clip is configured to receive the electrical signals from a user device and pass the electrical signals to the coil via the terminal ends.

To disrupt mitochondrial function in certain cells, controlling hardware causes a magnet to oscillate so as to generate an oscillating magnetic field. The oscillating magnetic field is applied to a volume of tissue including cells with degraded mitochondria to trigger apoptosis in the cells with degraded mitochondria.

Disclosed herein are systems and methods for providing a portable magnetic field therapy system for inducing an effect of a chemical or biochemical agent to a mammalian subject, such as for the treatment of diseases and adverse health conditions.

A device for treating the prostate and hemorrhoids is proposed, the device including: an anal insertion part including a body module including a first rechargeable battery charged when DC power is applied therein, a first wireless communication device wirelessly transmitting and receiving an electric signal, and an output circuit outputting a current according to the electric signal output from the first wireless communication device, a plurality of electrodes provided in a direction perpendicular to the body module and installed apart along a longitudinal direction on an outer circumferential surface to receive the current applied thereto, and a probe module including a vibrating element installed therein to generate vibration when the current is applied, a heating element generating heat, and a magnet installed at an upper end therein to generate a magnetic force; and a controller provided with a second rechargeable battery, a second wireless communication device, and a control module.