Devices, systems and methods are disclosed for treating or preventing a developmental disorder, such as attention-deficit hyperactivity disorder (ADHD), an autism spectrum disorder, Asperger syndrome, childhood disintegrative disorder, overactive disorder, pervasive developmental disorder. A device comprises an electrode having a contact surface for contacting an outer skin surface of a patient and a power source coupled the electrode. The power source generates and transmits an electrical impulse having a frequency of about 1 kHz to about 20 kHz through the contact surface and the outer skin surface to a nerve within the patient. The electrical impulse is sufficient to modify the behavioral disorder in the patient.

Neuromodulation is achieved by administering variable pulse electric or magnetic stimulation to a patient in need thereof. The neuromodulation can inhibit or enhance neuronal-synaptic transmission or muscle-synaptic transmission between neuron and muscle fibers The variable pulse electric or magnetic stimulation varies based on one or more mean and standard deviations of biological variables. Biological variables include heart rate variability, EEG variability, EMG variability and the frequency of activity measured in the spinal cord. The invention also includes devices that deliver the variable electric or magnetic pulses to the patient. Magnetic stimulation can be provided by electromagnetic or solid magnet stimulation.

Neuromodulation is achieved by administering variable pulse electric or magnetic stimulation to a patient in need thereof. The neuromodulation can inhibit or enhance neuronal-synaptic transmission or muscle-synaptic transmission between neuron and muscle fibers The variable pulse electric or magnetic stimulation varies based on one or more mean and standard deviations of biological variables. Biological variables include heart rate variability, EEG variability, EMG variability and the frequency of activity measured in the spinal cord. The invention also includes devices that deliver the variable electric or magnetic pulses to the patient. Magnetic stimulation can be provided by electromagnetic or solid magnet stimulation.

A system, device and method are provided for exposing a patient to therapeutic resonant frequency patterns (RFP) for therapy and treatment of a patient, for example, biological tissue such as muscle, tendon, ligament, and nerve tissue. The resonance frequencies originate from many bioactive substances, pharmaceuticals or other compounds, and key frequencies of the RFP of a compound can be replicated and then delivered to a patient using an electromagnetic catalyst to provide therapeutic benefits. RFPs can be imprinted in a separate device using a plasma imprinting device and method. This separate device can be actively excited by a delivery mechanism that uses electromagnetic or mechanical waves to interact with the device. The actively excited device transmits the RFPs or therapeutic resonant frequency patterns to the patient for similar enhancements and therapeutic benefits.

A system, device and method are provided for exposing a patient to therapeutic resonant frequency patterns (RFP) for therapy and treatment of a patient, for example, biological tissue such as muscle, tendon, ligament, and nerve tissue. The resonance frequencies originate from many bioactive substances, pharmaceuticals or other compounds, and key frequencies of the RFP of a compound can be replicated and then delivered to a patient using an electromagnetic catalyst to provide therapeutic benefits. RFPs can be imprinted in a separate device using a plasma imprinting device and method. This separate device can be actively excited by a delivery mechanism that uses electromagnetic or mechanical waves to interact with the device. The actively excited device transmits the RFPs or therapeutic resonant frequency patterns to the patient for similar enhancements and therapeutic benefits.

Certain aspects relate to systems and techniques for an orthopedic treatment system. In one aspect, the system includes a body unit configured to attach to an orthopedic bone plate, an electromagnetic field emitter positioned within the body unit, the electromagnetic field emitter configured to project an electromagnetic field at a therapeutic frequency for a therapeutic duration. The system may further include an internal power source positioned within the body unit, the internal power source configured to provide electrical current to the electromagnetic field emitter. The system may also include a receiving coil positioned within the body unit, the receiving coil configured to receive power from an external power source, the external power source positioned outside the body unit.

Certain aspects relate to systems and techniques for an orthopedic treatment system. In one aspect, the system includes a body unit configured to attach to an orthopedic bone plate, an electromagnetic field emitter positioned within the body unit, the electromagnetic field emitter configured to project an electromagnetic field at a therapeutic frequency for a therapeutic duration. The system may further include an internal power source positioned within the body unit, the internal power source configured to provide electrical current to the electromagnetic field emitter. The system may also include a receiving coil positioned within the body unit, the receiving coil configured to receive power from an external power source, the external power source positioned outside the body unit.

A measurement system includes a container configured to contain a solvated target molecule and at least one magnetoresistive (MR) sensor device including at least one MR sensor disposed near the container and configured to measure a magnetic field generated by the solvated target molecule, each of the at least one MR sensor including a pin layer having a pinned direction of magnetization, a free layer having a direction of magnetization that varies with an applied magnetic field, and a non-conductive layer separating the pin layer and the free layer.

A measurement system includes a container configured to contain a solvated target molecule and at least one magnetoresistive (MR) sensor device including at least one MR sensor disposed near the container and configured to measure a magnetic field generated by the solvated target molecule, each of the at least one MR sensor including a pin layer having a pinned direction of magnetization, a free layer having a direction of magnetization that varies with an applied magnetic field, and a non-conductive layer separating the pin layer and the free layer.

Described herein are high-power pulsed electromagnetic field (PEMF) applicator apparatuses. These apparatuses are configured to drive multiple applicators to concurrently deliver high-power PEMF signals to tissue. The apparatuses may be further configured to wirelessly communicate with local computing device and a remote server for patient monitoring, prescription and/or device servicing.