Controlled delivery of magnetic particles (e.g., nanoparticles) in combination with therapeutic, diagnostic and/or theranostic agents is described. The magnetic particles may be delivered through a catheter to a location adjacent a therapeutic and/or diagnostic target or region.

Controlled delivery of magnetic particles (e.g., nanoparticles) in combination with therapeutic, diagnostic and/or theranostic agents is described. The magnetic particles may be delivered through a catheter to a location adjacent a therapeutic and/or diagnostic target or region.

Helmets for applying a magnetic field to the head of a subject, comprising: a housing comprising a concave surface configured to receive a portion of the head of the subject; a motor coupled to one or more of: a first permanent magnet via a first axle along a first axis of rotation, wherein the first axle drives movement of the first magnet; a second magnet via a second axle along a second axis of rotation wherein the second axle drives movement of the second magnet; and a third magnet via a third axle along the third axis of rotation wherein the third axle drives movement of the third magnet, wherein the axes are parallel; and a fit mechanism comprising a adjuster coupled to the first magnet, wherein movement of the adjustor moves the first magnet independently of the second or the third magnet.

Helmets for applying a magnetic field to the head of a subject, comprising: a housing comprising a concave surface configured to receive a portion of the head of the subject; a motor coupled to one or more of: a first permanent magnet via a first axle along a first axis of rotation, wherein the first axle drives movement of the first magnet; a second magnet via a second axle along a second axis of rotation wherein the second axle drives movement of the second magnet; and a third magnet via a third axle along the third axis of rotation wherein the third axle drives movement of the third magnet, wherein the axes are parallel; and a fit mechanism comprising a adjuster coupled to the first magnet, wherein movement of the adjustor moves the first magnet independently of the second or the third magnet.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently tune the brain and affect mood, focus, and cognition of subjects.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently tune the brain and affect mood, focus, and cognition of subjects.

A portable apparatus for generating an induced low-frequency sinusoidal electric current in an area of the human body, comprises four angular magnet sectors inscribed within the same circle, centered on the same axis of rotation and spaced angularly apart from one another, the polarity of two adjacent angular magnet sectors being opposed, and means for rotating at a predetermined speed the angular magnet sectors about the axis of rotation such as to generate an induced sinusoidal current at a predefined frequency. Each angular magnet sector comprises one and the same geometrical shape with an internal angular opening of 90 , an external angular opening between 20 and 50, and two lateral edges defining a radius extending over a distance which is between one-third and two-thirds of a distance separating the axis of rotation from the free end of the magnet sectors.

A portable apparatus for generating an induced low-frequency sinusoidal electric current in an area of the human body, comprises four angular magnet sectors inscribed within the same circle, centered on the same axis of rotation and spaced angularly apart from one another, the polarity of two adjacent angular magnet sectors being opposed, and means for rotating at a predetermined speed the angular magnet sectors about the axis of rotation such as to generate an induced sinusoidal current at a predefined frequency. Each angular magnet sector comprises one and the same geometrical shape with an internal angular opening of 90 , an external angular opening between 20 and 50, and two lateral edges defining a radius extending over a distance which is between one-third and two-thirds of a distance separating the axis of rotation from the free end of the magnet sectors.

Magnetic particle actuating systems may include a magnet system configured to generate a magnetic field that includes a field-free region. A corresponding control system can be configured to control the magnet system to create a field-free region at least partially matching a target region. An excitation system can be configured to generate an excitation field to cause actuation of magnetic nanoparticles in an actuation region.

Magnetic particle actuating systems may include a magnet system configured to generate a magnetic field that includes a field-free region. A corresponding control system can be configured to control the magnet system to create a field-free region at least partially matching a target region. An excitation system can be configured to generate an excitation field to cause actuation of magnetic nanoparticles in an actuation region.