The disclosure provides systems for ultrasound-induced thrombolysis with magnetic microbubbles under a rotational/alternating magnetic field, sonothrombolysis systems with magnetic microbubbles and optional nanodroplets for inducing thrombolysis under an acoustic field, and a rotational/alternating magnetic field, and methods of treating patients with blood clots using the sonothrombolysis systems of the present disclosure.

The disclosure provides systems for ultrasound-induced thrombolysis with magnetic microbubbles under a rotational/alternating magnetic field, sonothrombolysis systems with magnetic microbubbles and optional nanodroplets for inducing thrombolysis under an acoustic field, and a rotational/alternating magnetic field, and methods of treating patients with blood clots using the sonothrombolysis systems of the present disclosure.

Apparatus for applying Transcranial Magnetic Stimulation (TMS) to an individual, wherein the apparatus comprises: a head mount for disposition on the head of an individual; and a plurality of magnet assemblies for releasable mounting on the head mount, wherein each of the magnet assemblies comprises a permanent magnet, and at least one of (i) a movement mechanism for moving the permanent magnet and/or (ii) a magnetic shield shutter mechanism, for selectively providing a rapidly changing magnetic field capable of inducing weak electric currents in the brain of an individual so as to modify the natural electrical activity of the brain of the individual; wherein the number of magnet assemblies mounted on the head mount, their individual positioning on the head mount, and their selective provision of a rapidly changing magnetic field is selected so as to allow the spatial, strength and temporal characteristics of the magnetic field to be custom tailored for each individual, whereby to provide individual-specific TMS therapy, to assist in diagnosis or to map out brain function in neuroscience research.

Apparatus for applying Transcranial Magnetic Stimulation (TMS) to an individual, wherein the apparatus comprises: a head mount for disposition on the head of an individual; and a plurality of magnet assemblies for releasable mounting on the head mount, wherein each of the magnet assemblies comprises a permanent magnet, and at least one of (i) a movement mechanism for moving the permanent magnet and/or (ii) a magnetic shield shutter mechanism, for selectively providing a rapidly changing magnetic field capable of inducing weak electric currents in the brain of an individual so as to modify the natural electrical activity of the brain of the individual; wherein the number of magnet assemblies mounted on the head mount, their individual positioning on the head mount, and their selective provision of a rapidly changing magnetic field is selected so as to allow the spatial, strength and temporal characteristics of the magnetic field to be custom tailored for each individual, whereby to provide individual-specific TMS therapy, to assist in diagnosis or to map out brain function in neuroscience research.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for treatment of anxiety. Described are methods and devices to treat anxiety that involves no medication. Methods and devices described herein use alternating magnetic fields to gently tune the brain and affect symptoms of anxiety.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for treatment of anxiety. Described are methods and devices to treat anxiety that involves no medication. Methods and devices described herein use alternating magnetic fields to gently tune the brain and affect symptoms of anxiety.

A system and method for providing transcranial magnetic stimulation (TMS) based on electroencephalogram (EEG) data. The system and method may include a portable neuro-electroencephalogram synchronization therapy (NEST) system for capturing EEG data from a patient. The system and method may also include an electrophysiology database and customized TMS treatment system for receiving the EEG data from the portable NEST system. The electrophysiology database and customized TMS treatment system may determine a TMS treatment based on the received EEG data. The portable NEST system may provide synchronized TMS based on the determined TMS treatment.

A system and method for providing transcranial magnetic stimulation (TMS) based on electroencephalogram (EEG) data. The system and method may include a portable neuro-electroencephalogram synchronization therapy (NEST) system for capturing EEG data from a patient. The system and method may also include an electrophysiology database and customized TMS treatment system for receiving the EEG data from the portable NEST system. The electrophysiology database and customized TMS treatment system may determine a TMS treatment based on the received EEG data. The portable NEST system may provide synchronized TMS based on the determined TMS treatment.

A method for providing transcranial magnetic stimulation (TMS) based on electroencephalogram (EEG) data. The method may include use of a portable neuro-electroencephalogram synchronization therapy (NEST) system for capturing EEG data from a patient. The method may also include use of an electrophysiology database and customized TMS treatment system for receiving the EEG data from the portable NEST system. The electrophysiology database and customized TMS treatment system may determine a TMS treatment based on the received EEG data. The portable NEST system may deliver synchronized TMS based on the determined TMS treatment.

A networked system for providing transcranial magnetic stimulation (TMS) based on analyzed electroencephalogram (EEG) data is disclosed. The networked system interfaces with portable neuroelectroencephalogram synchronization therapy (NEST) devices for capturing EEG data from a patient. The network also may also include an electrophysiology database and customized TMS treatment system for receiving the EEG data from the portable NEST system. The electrophysiology database and customized TMS treatment system are configurable and operable to determine a TMS treatment based on the received EEG data. The portable NEST system may provide synchronized TMS based on the determined TMS treatment.