Systems and methods for applying and/or receiving electrical, magnetic, magnetoelectric, vibratory, or electromagnetic signals to biological tissues are described. In some embodiments, a system including a body and an electrode may be placed in contact with a biological tissue portion. A force may be applied to the body such that the body plastically deforms to adapt to a shape of the biological tissue portion, and the electrode may be used to apply and/or receive an electrical signal via the biological tissue portion.

A method for disrupting mitochondrial function in cells includes causing one or more magnets to oscillate along at least a first axis of rotation and a second axis of rotation substantially orthogonal to the first axis of rotation, so as to generate an oscillating magnetic field. To this end, the method includes selecting the first axis of rotation, applying an oscillation pattern along the first axis of rotation, the oscillating including a ramp-up period for an oscillation frequency, a ramp-down period for the oscillation frequency, and an inactive period following the ramp-down period, selecting the second axis of rotation, and applying the oscillation pattern along the second axis of rotation. The method further includes applying the oscillating magnetic field to a tissue comprising cancer cells to trigger apoptosis in the cancer cells.

A method for disrupting mitochondrial function in cells includes causing one or more magnets to oscillate along at least a first axis of rotation and a second axis of rotation substantially orthogonal to the first axis of rotation, so as to generate an oscillating magnetic field. To this end, the method includes selecting the first axis of rotation, applying an oscillation pattern along the first axis of rotation, the oscillating including a ramp-up period for an oscillation frequency, a ramp-down period for the oscillation frequency, and an inactive period following the ramp-down period, selecting the second axis of rotation, and applying the oscillation pattern along the second axis of rotation. The method further includes applying the oscillating magnetic field to a tissue comprising cancer cells to trigger apoptosis in the cancer cells.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently tune the brain and affect mood, focus, and cognition of subjects.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for a number of disorders. Described are methods and devices to treat disorders that involves no medication. Methods and devices described herein use alternating magnetic fields to gently tune the brain and affect mood, focus, and cognition of subjects.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for treatment of anxiety. Described are methods and devices to treat anxiety that involves no medication. Methods and devices described herein use alternating magnetic fields to gently tune the brain and affect symptoms of anxiety.

Described are methods, devices, and systems for a novel, inexpensive, easy to use therapy for treatment of anxiety. Described are methods and devices to treat anxiety that involves no medication. Methods and devices described herein use alternating magnetic fields to gently tune the brain and affect symptoms of anxiety.

A transcranial magnetic stimulation device in accordance with embodiments of the present invention comprises a head mount for disposition on a head of a patient and configured with a plurality of attachment points, a plurality of magnetic assembly devices connected to the plurality of attachment points, a given magnetic assembly device equipped with an actuator device to actuate a magnet, is addressable, and configured to receive a control signal addressed to the given magnetic assembly device, and a processor having a memory and configured by program code. The processor is configured to: select one or more treatment protocol units, generate a control signal using at least information contained in the selected treatment protocol units, energize at least one magnetic assembly device over a period of time to cause the magnet to actuate according to the control signal, and monitor the patient response to energizing to addressable actuator.

Helmets for applying a magnetic field to the head of a subject, comprising: a housing comprising a concave surface configured to receive a portion of the head of the subject; a motor coupled to one or more of: a first permanent magnet via a first axle along a first axis of rotation, wherein the first axle drives movement of the first magnet; a second magnet via a second axle along a second axis of rotation wherein the second axle drives movement of the second magnet; and a third magnet via a third axle along the third axis of rotation wherein the third axle drives movement of the third magnet, wherein the axes are parallel; and a fit mechanism comprising a adjuster coupled to the first magnet, wherein movement of the adjustor moves the first magnet independently of the second or the third magnet.

Helmets for applying a magnetic field to the head of a subject, comprising: a housing comprising a concave surface configured to receive a portion of the head of the subject; a motor coupled to one or more of: a first permanent magnet via a first axle along a first axis of rotation, wherein the first axle drives movement of the first magnet; a second magnet via a second axle along a second axis of rotation wherein the second axle drives movement of the second magnet; and a third magnet via a third axle along the third axis of rotation wherein the third axle drives movement of the third magnet, wherein the axes are parallel; and a fit mechanism comprising a adjuster coupled to the first magnet, wherein movement of the adjustor moves the first magnet independently of the second or the third magnet.