Embodiments of an improved photodynamic therapy device are provided. An example of the device includes an irradiation head having a first end and a surface at a second end, the surface having a radius of curvature. The device also includes a plurality of light sources disposed on the curved surface. The plurality of light sources are configured to emit light having at least one wavelength corresponding approximately to an excitation peak of at least one photosensitizer. The light emitted by the plurality of light sources is focused to a focal point based on the radius of curvature of the surface and a target surface (e.g., a corneal surface of an eye) may be positioned at the focal point for treatment.

A material for controlling light incident beneficial for treating skin conditions, wherein the material is arranged in a grid structure, wherein the grid structure is configured to have at least one grid portion, which includes one or more layers, wherein the at least one grid portion is configured in the article or apparatus to target an area of skin for treatment, the one or more layers of the at least one grid portion include at least one filter layer, configured to block light incident within a target wavelength range, based on filter layer material, which blocks light within the target range associated with a skin treatment, of each respective layer of the portion of the grid structure, wherein the filter layer is attached to the grid structure at the portion and configured to pass the at least one wavelength to treat an area of skin; and a protective layer, different from the at least one filtering grid portion of the grid structure, for reducing skin exposure to at least one of harmful light and non-beneficial light, by blocking at least one of harmful and non-beneficial wavelengths of the light passing through the filter layer material.

The present disclosure relates to systems, methods, and uses of systems treating a skin condition with phototherapy. A system comprises (a) a phototherapy device comprising a phototherapy light source; (b) a patient computing device comprising a processor and a memory, the patient computing device configured to: transmit a first signal to the phototherapy device enabling operation of the phototherapy device according to one or more conditional prescription parameters, activate the phototherapy light source, and transmit a second signal reporting operation of the phototherapy device; and (c) a server configured to communicate with the patient computing device and receive the second signal. Also disclosed are systems, methods and compositions for controlling phototherapy treatments of the skin comprising (a) incorporating sun exposure into a prescribed phototherapy treatment; (b) quantitative measurement of erythema using digital image processing; (c) computer aided guidance for administration of targeted phototherapy; (d) treatment recommendations from outcome based analytics of a population of connected phototherapy devices; (e) an emollient with UV fading dye to visibly identify treated areas in the administration of targeted phototherapy.

The present disclosure relates to systems, methods, and uses of systems treating a skin condition with phototherapy. A system comprises (a) a phototherapy device comprising a phototherapy light source; (b) a patient computing device comprising a processor and a memory, the patient computing device configured to: transmit a first signal to the phototherapy device enabling operation of the phototherapy device according to one or more conditional prescription parameters, activate the phototherapy light source, and transmit a second signal reporting operation of the phototherapy device; and (c) a server configured to communicate with the patient computing device and receive the second signal. Also disclosed are systems, methods and compositions for controlling phototherapy treatments of the skin comprising (a) incorporating sun exposure into a prescribed phototherapy treatment; (b) quantitative measurement of erythema using digital image processing; (c) computer aided guidance for administration of targeted phototherapy; (d) treatment recommendations from outcome based analytics of a population of connected phototherapy devices; (e) an emollient with UV fading dye to visibly identify treated areas in the administration of targeted phototherapy.

The invention relates to human targets of interest (TOI), anti-TOI ligands, kits compositions and method.

Systems tune, control, or remediate the intrinsic Circadian clock. A light controller sets spectral distribution, intensity of a bioactive spectral band to shift or entrain circadian response to enhance performance and/or synchronize with local or expected conditions. The systems enhance performance under conditions that might be changing, disrupted, or otherwise present an irregular phase or unnatural change in the subject's circadian status, for example, due to geographically discontinuous activity or spectrally deficient workplace illumination, or due to divergent individual sleep/wake behaviors of subjects in a structured group activity. An illumination recipe that compensates for the deficiency of lighting or of participant sleep or behavior patterns, or age- or disease-related changes, to evoke, shift, or align circadian response and improve behaviors such as classroom alertness, relaxation, excitability, attention, or focus. Systems may receive sensed light values and automatically apply high- and/or low-CER illumination to effect the intended circadian phase.

The present invention relates to a lifting band comprising: a band member provided in the form of a plate having elasticity and resilience and having a predetermined area; at least one light source part disposed on one surface of the band member and including a plurality of LEDs that, when power is applied, emit light of a predetermined wavelength band so as to improve the skin; and a cover member which is fixed to one surface of the band member so as to cover the at least one light source part.

The present invention relates to a lifting band comprising: a band member provided in the form of a plate having elasticity and resilience and having a predetermined area; at least one light source part disposed on one surface of the band member and including a plurality of LEDs that, when power is applied, emit light of a predetermined wavelength band so as to improve the skin; and a cover member which is fixed to one surface of the band member so as to cover the at least one light source part.

The present invention relates to a lighting device and a control method therefor. The lighting device according to the present invention comprises: a light source unit comprising one or more light emitting elements; a first body to which the light source unit is mounted; a second body; a sensor unit for sensing at least one of a relative posture and a relative position of the first body to the second body; and a control unit for controlling the light emitting operation of the light source unit on the basis of at least one of the relative posture and the relative position of the first body.

An interoperative light therapy apparatus and method are disclosed. The apparatus includes an excitation light source, a plurality of light emitting devices and a plurality of light detecting fibers, wherein the plurality of light emitting devices produce a fluorescence light in cancerous cells of a patient treated with a photosensitizing medication. The fluorescence light is collected by the plurality of detector fibers and a digital spatial image of the cancerous cells is produced. The digital spatial image is useful for targeting the cancerous cells in a subsequent resection procedure. An interoperative light therapy apparatus is disclosed that further include a therapy light source that can deliver therapy light to the cancerous cells using the digital spatial image in the subsequent resection procedure.