The present invention provides a myopia-preventing high intensity illumination apparatus for illuminating eyeballs and surrounding tissues via light that penetrating periorbital skin, subcutaneous tissue, then pass through cornea, iris, uvea, sclera and choroid, comprising a light source and a controller electrically connects to the light source, wherein the light source is projects to and illuminates on skin surrounding eyes, penetrates and enters subcutaneous tissue, iris, ciliary body and lens, as well as penetrates peripheral tissues of eyeballs, sclera, uvea, choroid and retinal pigment epithelium, and indirectly enters into vitreous and retina, so as to prevent myopia from further worsening by inducing microscopic biochemical reactions.

Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by application of an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The methods may further be performed by application of an initiation energy to a subject in situ to activate a pharmaceutical agent directly or via an energy modulation agent, optionally in the presence of one or more plasmonics active agents, thus producing an effect on or change to the target structure. Kits containing products or compositions formulated or configured and systems for use in practicing these methods.

Provided is a skin care device including a head part brought into contact with skin of a user, a battery configured to supply power for operation of the head part, a body part having a fastening portion provided at one end to which the head part is fastened and provided with the battery therein, and a cap assembly detachably attached to one end of the body part and forming an accommodation space configured to accommodate the head part, wherein the cap assembly includes a sterilization module disposed to irradiate ultraviolet light toward the head part when the cap assembly accommodates the head part.

A light treatment system includes: a probe configured to be inserted into a body cavity, the probe including an optical fiber configured to propagate light, and a light emitter that is provided at a distal end of the optical fiber, the emitter being configured to emit the light; a balloon catheter into which the probe is inserted, the balloon catheter including a distal end portion that is to be inserted into the body cavity and that is to be dilated by being supplied with a liquid including air bubbles; and an air bubble generator configured to generate the air bubbles to be included in the liquid and change a property of the air bubbles.

Provided herein are methods and systems for modulating temporal patterns of neuronal activity in the brain. A method of the present disclosure may include using optogenetics to stimulate a one or more of thalamocortical projections, thalamic relay neurons, cortical projection neurons, cell bodies in a thalamic submedial nucleus, and cell bodies in the VLO in the brain, in conjunction with fMRI of different regions of the brain to directly visualize the global influence of the VLO's afferent and efferent connections, and characterize how different temporal patterns of activity in the VLO circuit affect brain dynamics by driving its input and output at distinct frequencies.

A light filter (100) includes at least one layer of binder matrix (110) and a multitude of transparent crystals (120). The multitude of transparent crystals (120) are irregularly and laterally dispersed in the at least one layer of binder matrix (110), such that light passing through the light filter (100) is separated into different wavelengths and polarized into different orientations.

A light filter (100) includes at least one layer of binder matrix (110) and a multitude of transparent crystals (120). The multitude of transparent crystals (120) are irregularly and laterally dispersed in the at least one layer of binder matrix (110), such that light passing through the light filter (100) is separated into different wavelengths and polarized into different orientations.

Provided herein is a multifunctional aesthetic system including a housing, an electromagnetic array situated in the housing and having one or more electromagnetic radiation (EMR) sources, a controller in electronic communication with the array to operate the one or more of the EMR sources to direct the EMR beam to a treatment area, and one or more sensors in electronic communication with the controller for providing feedback to the controller based on defined parameters to allow the controller to adjust at least one operating condition of the multifunctional system in response to the feedback.

The present invention relates generally to a device for providing multi-modal energy therapy to treat neurogenerative disorders, and more particularly to a device providing multi-modal neuro-supportive energy therapy to a person via a daily session in a single facility. The device provides safe, well studied energy therapies in a controlled manner to stimulate neuronal mitochondrial activity which powers the brains neurons and is often defective in neurodegenerative disease states. Selected energy delivery mechanisms and frequencies are employed to stabilize microglial activity and promote microglial homeostasis and neuroprotective secretions, including mitochondrial melatonin and other neuroprotective factors. In addition to practicality, the combination of these proven therapeutic modalities into a single device may offer synergies not found when they are employed alone. This focused combination of these unique energy based therapies may offer new hope to slow, stop, reverse or mitigate neurogenerative disorders, such as Alzheimer's, ALS and Parkinson's diseases.

A device and method for disinfecting and/or enhancing healing of a wound or surgical site facilitates placing a light-emitting device with a frame having a central void, the central void adapted to surround the wound or surgical site; an illumination source disposed on the frame for directing safe, therapeutic light centrally towards the underlying wound or surgical site; and the transparent central void enabling visualization and clinical monitoring of the underlying wound or surgical site.