A device for measuring radiation dosage is disclosed, comprising a flexible sheet, one or more detector assemblies disposed on the sheet, and detector retaining means for retaining the one or more detector assemblies on the sheet such that the one or more detector assemblies adopt the same curvature as the sheet when the sheet is deformed. Each one or more detector assembly comprises a plurality of beads threaded onto a fibre, the plurality of beads comprising radiation-sensitive material for recording information about a radiation dosage to which each bead is exposed, and the detector retaining means is configured to permit each one or more detector assembly to be subsequently detached from the sheet without removing the plurality of beads from the fibre. A method of detecting radiation dosage using the device is also disclosed.

A nutritional supplement containing fish oil and selenium has been identified that enhances immunotherapy of tumors, particularly in regard to reducing PDL-1 expression. A formulation for such a supplement that is both well tolerated and palatable is also provided.

The dose rate of voxels within a particle beam (e.g., proton beam) treatment field delivered using pencil beam scanning (PBS) is calculated, and a representative dose rate for the particle beam treatment field is reported. The calculations account for a dose accumulation in a local region or a sub-volume (e.g., a voxel) as a function of time.

The dose rate of voxels within a particle beam (e.g., proton beam) treatment field delivered using pencil beam scanning (PBS) is calculated, and a representative dose rate for the particle beam treatment field is reported. The calculations account for a dose accumulation in a local region or a sub-volume (e.g., a voxel) as a function of time.

Provided are methods relating to compositions that include a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101.

Provided herein are pharmaceutical compositions comprising carotenoids, including liposomes that encapsulate carotenoids including ionizable carotenoids such as trans-crocetin. The provided compositions have uses in treating diseases, disorders and conditions associated with, but not limited to, infection, endotoxemia, inflammation, sepsis, ischemia, hypoxia, shock, stroke, lung injury, wound healing, traumatic injury, reperfusion injury, cardiovascular disease, kidney disease, liver disease, inflammatory disease, metabolic disease, pulmonary disorders, blood related disorders and hyperproliferative diseases such as cancer. Methods of making, delivering, and using the pharmaceutical compositions are also provided.

A patient treatment table for prone patient breast examination and treatment is described. The table may be in the form of a table base and table extension, the table extension being removably attached to the table base. The patient treatment table extension includes one or more hand rails for grasping by the patient above and along one or both longitudinal sides of the device to assist the patient in getting onto the treatment table. The handrails are mounted such that they can be removed or swung out of the way of medical equipment once the patient is positioned on the table. The table may also be in the form of a couch-top overlay.

A neutron capture therapy system, including a vacuum tube for transmitting a charged particle beam, a neutron generating part for generating a neutron beam, and a beam shaping assembly for shaping the neutron beam. The beam shaping assembly is provided with an accommodating part. The neutron generating part is disposed at an end of the vacuum tube. The vacuum tube has a first position and a second position. The neutron capture therapy system further includes a removal device, which includes a moving part that drives the vacuum tube to move. The moving part has a third position and a fourth position. When the moving part is in the third position, the vacuum tube is in the first position. When the moving part is in the fourth position, the vacuum tube is in the second position, and the neutron generating part is located at the outer side of the beam shaping assembly.

A memory has a fluence map that corresponds to a particular patient stored therein. This memory also has at least one deep learning model stored therein trained to deduce a leaf sequence for a multi-leaf collimator from a fluence map. A control circuit operably coupled to that memory iteratively optimizes a radiation treatment plan to administer therapeutic radiation to that patient by, at least in part, generating a leaf sequence as a function of the at least one deep learning model and the fluence map that corresponds to the patient.

Embodiments described herein provide for recommending radiotherapy treatment attributes. A machine learning model predicts the preference of a medical professional and provides relevant suggestions (or recommendations) of radiotherapy treatment attributes for various categories of radiotherapy treatment. Specifically, the machine learning model predicts field geometry attributes from various field geometry attribute options for various field geometry attribute categories. The machine learning model is conditioned on patient data such as medical images and patient information. The machine learning model is trained in response to cumulative reward information associated with a medical professional accepting the provided/displayed recommendations.