A61N5/10

Live view camera for radiation therapy

An apparatus for use with a medical system, the medical system comprising a medical device configured to treat and/or image a patient, includes: a camera configured to capture an image of a first mirror, wherein the image of the first mirror contains an image of at least a part of the patient and/or an image of at least a part of the medical system; wherein the camera comprises electronics that are not radiation-hard.

Assessing treatment parameters for radiation treatment planning

Information associated with a radiation treatment plan includes, for example, values of dose per voxel in a target volume, values of dose rate per voxel in the target volume, and values of parameters used when generating the values of dose per voxel and the values of dose rate per voxel. Renderings that include, for example, a rendering of an image of or including the target volume, and a rendering of selected values of the radiation treatment plan, are displayed. When a selection of a region of one of the renderings is received, a displayed characteristic of another one of the renderings is changed based on the selection.

CORRECTING THE MAGNETIC FIELD OF A MEDICAL APPARATUS WITH A GANTRY
20180003789 · 2018-01-04 ·

A method of correcting a magnetic field of a medical apparatus (300) comprising a magnetic resonance imaging system (302). The MRI system includes a magnet (306) for generating the magnetic field within an imaging zone 318. The magnet generates a magnetic field with a zero crossing (346, 404) outside of the imaging zone. The medical apparatus further comprises a gantry (332) configured for rotating a ferromagnetic component (336, 510) about a rotational axis (333). The method comprises the step of installing (100, 200) a magnetic correcting element (348, 900, 1000) located on a radial path (344, 504) perpendicular to the rotational axis. The magnetic correcting element is positioned on the radial path such that change in the magnetic field within the imaging zone due to the ferromagnetic component is reduced. The method further comprises repeatedly: measuring (102, 202, 1204) the magnetic field within the imaging zone; determining (104, 204, 1206) the change in the magnetic field in the imaging zone; and adjusting (106, 206, 1208) the position of the magnetic correcting element along the radial path if the change in the magnetic field is above a predetermined threshold.

SYSTEMS AND METHODS FOR USE IN EMISSION GUIDED RADIATION THERAPY
20180001109 · 2018-01-04 ·

Described herein are systems and methods for positioning a radiation source with respect to one or more regions of interest in a coordinate system. Such systems and methods may be used in emission guided radiation therapy (EGRT) for the localized delivery of radiation to one or more patient tumor regions. These systems comprise a gantry movable about a patient area, where a plurality of positron emission detectors, a radiation source are arranged movably on the gantry, and a controller. The controller is configured to identify a coincident positron annihilation emission path and to position the radiation source to apply a radiation beam along the identified emission path. The systems and methods described herein can be used alone or in conjunction with surgery, chemotherapy, and/or brachytherapy for the treatment of tumors.

ISOINDOLINE OR ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I):

##STR00001##

wherein Het, R.sub.3, R.sub.4, R.sub.5, R.sub.7, R.sub.8, R.sub.9, T, p, p′, q, and q′ are as defined in the description.

Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.

ISOINDOLINE OR ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds of formula (I):

##STR00001##

wherein Het, R.sub.3, R.sub.4, R.sub.5, R.sub.7, R.sub.8, R.sub.9, T, p, p′, q, and q′ are as defined in the description.

Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.

BEAM SHAPING ASSEMBLY FOR NEUTRON CAPTURE THERAPY
20180001112 · 2018-01-04 ·

A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The material of the moderator is subjected to a powder sintering process using a powder sintering device so as to change powders or a power compact into blocks. The reflector leads the neutrons deviated from the main axis back. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

GUIDED CHARGED PARTICLE IMAGING/TREATMENT APPARATUS AND METHOD OF USE THEREOF
20180001110 · 2018-01-04 ·

The invention comprises a method and apparatus for tracking and/or imaging impact of a particle beam treating a tumor using one or more imaging systems positionable about the tumor, such as a positron emission tracking and/or imaging system, where resulting tracking/imaging data: dynamically determines a treatment beam position, tracks a history of treatment beam positions, guides the treatment beam, and/or images a tumor before, during, and/or after treatment with the charged particle beam.

NON-TOXIC FORMULATIONS OF RADIO-LUMINESCENT NANOPARTICLES FOR USE AS CANCER RADIO-SENSITIZING AGENTS
20180008733 · 2018-01-11 · ·

The invention relates generally to a formulation in which metal tungstate or metal molybdate particles are encapsulated within biocompatible, diseased cell-targeting polymeric coatings. Such formulations render metal tungstate or metal molybdate particles suitable for in vivo biomedical imaging and therapeutic applications.

NON-TOXIC FORMULATIONS OF RADIO-LUMINESCENT NANOPARTICLES FOR USE AS CANCER RADIO-SENSITIZING AGENTS
20180008733 · 2018-01-11 · ·

The invention relates generally to a formulation in which metal tungstate or metal molybdate particles are encapsulated within biocompatible, diseased cell-targeting polymeric coatings. Such formulations render metal tungstate or metal molybdate particles suitable for in vivo biomedical imaging and therapeutic applications.