The present invention relates to an intravenous infusion dosage form comprising: an aqueous solution of pemetrexed or its pharmaceutically acceptable salt at a concentration ranging from 1.0 mg/ml to 20.0 mg/ml present in a multilayered flexible plastic infusion container, wherein the multilayered flexible plastic infusion container has an oxygen scavenger layer sandwiched between an outermost and an innermost layer of the container, the container being free of a polyimide and wherein the multilayered flexible plastic infusion container filled with the aqueous solution of pemetrexed is autoclavable.

Disclosed is a layered barrier film having a first product component and a second detachable carrier component. The first product component includes a layer of material selected from a group including polyethylenes, polyethylene copolymers, polypropylene copolymers, thermoplastic polyurethanes, thermoplastic polyester elastomers, thermoplastic polyamide elastomers, thermoplastic elastomer compounds, and/or blends thereof, and a second layer made from at least partially inorganic material. The first product component has high barrier properties and is very soft. The second detachable carrier component is a layer of material selected from a group including polyethylenes, polypropylenes, polyesters, polyamides, and/or blends thereof.

The invention relates to a multilayer packaging film comprising at least three different types of layers (A), (B), and (C): (A) is at least one outer layer, (B) is at least one passive oxygen barrier layer, (C) is at least one active oxygen scavenging layer, characterized in that the at least one outer layer (A) is a thermoplastic polymer; the at least one passive oxygen barrier layer (B) is selected from the group consisting of ethylene vinyl alcohol copolymers, polyvinylchloride, copolymers of polyvinyl chloride, polyvinyl alcohol, polyvinylidene dichloride, copolymers of polyvinylidene dichloride, polyacrylonitrils, copolymers of polyacrylonitrils, polyethylene terephthalate, polyethylene naphthalate, polyethylenefuranoate, polysiloxanes, and polyamides; the at least one active oxygen scavenging layer (C) comprises a) a plastic material which is a polyolefin, a polyolefin copolymer or a polystyrene, and additives (b) and (c), wherein b) is a polyterpenic resin; and c) is a transition metal catalyst

A multilayer body comprising a sealing layer (A) comprising a thermoplastic resin, an oxygen absorption layer (B) comprising a thermoplastic resin and iron powder, and an oxygen barrier layer (D) having oxygen barrier properties, the layers being laminated in a described order, wherein at least one of the sealing layer (A) and the oxygen absorption layer (B) comprises an ionomer as the thermoplastic resin.

A zeolite formulation has been identified that is to be included in an arrangement of barrier layers allowing for the entrapment of volatile organoleptic compound (VOCs), in particular, odor causing VOCs, between the barrier layers in order to contain the release of these compounds. The entrapment technique allows for extended time to adsorb, absorb or react such VOCs before they can be absorbed by the product surrounded by the packaging. A zeolite formulation of an odor scavenger layer not having any VOC barrier layers within the film is also disclosed having the capability to contain the release of hydrogen sulfide over a period of at least 20 days.

A multilayer body comprising a sealing layer (A) comprising a thermoplastic resin, an oxygen absorption layer (B) comprising a thermoplastic resin and iron powder, an odor absorption layer (C) comprising a thermoplastic resin and an inorganic base, and an oxygen barrier layer (D) having oxygen barrier properties, the layers being laminated in a described order.

The present invention relates to an intravenous infusion dosage form comprising: an aqueous solution of pemetrexed or its pharmaceutically acceptable salt at a concentration ranging from 1.0 mg/ml to 20.0 mg/ml present in a multilayered flexible plastic infusion container, wherein the multilayered flexible plastic infusion container has an oxygen scavenger layer sandwiched between an outermost and an innermost layer of the container, the container being free of a polyamide and wherein the multilayered flexible plastic infusion container filled with the aqueous solution of pemetrexed is autoclavable.

The present invention provides an oxygen absorber composition containing a hydrocarbon resin; an iron particle having an average particle diameter of 1.0 m or more and 200 m or less and having a BET specific surface area of 10 m.sup.2/g or more; and an aldehyde absorber capable of absorbing at least aldehyde compound, wherein the iron particle contains iron.

A laminated sheet or a container includes: an absorbing layer absorbing at least one of liquid and gas; a reinforcing layer laminated on the absorbing layer with an adhesive layer interposed therebetween; an aluminum layer laminated on the reinforcing layer with an adhesive layer interposed therebetween; and a barrier layer laminated on the aluminum layer with an adhesive layer interposed therebetween and suppressing entry of at least one of liquid and gas.

An oxygen-scavenging composition is provided that includes an oxygen-scavenging component and an oxidation catalyst. In preferred embodiments, the oxygen-scavenging composition includes a thermoplastic polymer that may optionally include the oxygen-scavenging composition as a portion thereof. In preferred embodiments, the composition is suitable for use in packaging articles.