A61P1/14

METHODS AND COMPOSITIONS TO SUPPORT THE GROWTH OR MAINTENANCE OF OXYGEN-SENSITIVE BACTERIA IN THE GASTROINTESTINAL TRACT

Methods and compositions to support the growth or maintenance of oxygen-sensitive bacteria in the gastrointestinal tract of an animal, preferably a mammal, are provided. Particularly, the methods for selectively enhancing the growth of beneficial anaerobic butyrate-producing bacteria, such as Faecaliumbacterium prausnitzii (F. prausnitzii).

METHODS AND COMPOSITIONS TO SUPPORT THE GROWTH OR MAINTENANCE OF OXYGEN-SENSITIVE BACTERIA IN THE GASTROINTESTINAL TRACT

Methods and compositions to support the growth or maintenance of oxygen-sensitive bacteria in the gastrointestinal tract of an animal, preferably a mammal, are provided. Particularly, the methods for selectively enhancing the growth of beneficial anaerobic butyrate-producing bacteria, such as Faecaliumbacterium prausnitzii (F. prausnitzii).

IMPROVEMENT OF INSOLUBLE FIBRE FERMENTABILITY AND SHORT CHAIN FATTY ACID PRODUCTION BY BIFIDOBACTERIUM LONGUM

The present invention relates to a Bifidobacterium longum probiotic for use to improve fermentability of a plant fibre during gastro-intestinal tract passage in a subject, wherein said plant fibre has an insoluble fraction of between 40 to 80% (w/w).

IMPROVEMENT OF INSOLUBLE FIBRE FERMENTABILITY AND SHORT CHAIN FATTY ACID PRODUCTION BY BIFIDOBACTERIUM LONGUM

The present invention relates to a Bifidobacterium longum probiotic for use to improve fermentability of a plant fibre during gastro-intestinal tract passage in a subject, wherein said plant fibre has an insoluble fraction of between 40 to 80% (w/w).

BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS

Methods of treating anti-inflammatory conditions through the use of boron-containing small molecules are disclosed.

Use of placental stem cells in treatment of acute kidney injury
11696930 · 2023-07-11 · ·

Provided herein are methods of using human placental stem cells in the treatment of subjects having acute kidney injury (AKI).

Development of amyloglucosidase as a medicinal food or dietary supplement

Embodiments of the disclosure include particular amyloglucosidase (AMG) compositions formulated as a nutriceutical or medicinal food, for example. The AMG compositions are formulated at a specific dosage and/or are lacking in one or more toxins or have substantially reduced levels of toxin, such as deoxynivalenol (vomit toxin). The AMG compositions are provided to individuals in need thereof, such as an individual with or at risk for congenital sucrase isomaltase syndrome, functional bowel disorders, small bowel bacterial overgrowth, protein-calorie malnutrition (marasmus), radiochemotherapy-induced mucositis and/or short-gut syndrome.

PHYTOTHERAPY COMPOSITION ASSOCIATED WITH POLYVITAMIN AND MINERAL SUPPLEMENTS

This invention is related to a phytotherapic composition associated to polyvitamin and mineral supplements for anti-hepatotoxic and antioxidant treatment, besides helping hepatic protein synthesis and the circulatory system and contributing directly to neurotransmitter synthesis, whereby its hepatoprotective action helps patients with liver diseases or developing hepatobiliary disorders, providing relief in dyspepsia and liver-related digestive problems.

COMPOSITIONS FOR USE IN THE REDUCTION OF PAIN AND/OR PERCEPTION OF PAIN IN INFANTS AND YOUNG CHILDREN

The present invention relates to compositions comprising a mix of human milk oligosaccharides consisting of 2′-fucosyllactose and difucosyllactose, for use in the reduction of pain and/or perception of pain in an infant or in a young child. The compositions are particularly effective in the restoration of the sensitivity of the bi-directional pain transmission pathways in the gut-brain axis to normal levels. The compositions are in particular useful in reducing abdominal pain, such as pain associated with gastrointestinal discomfort, functional gastrointestinal disorders, and/or gastrointestinal diseases and consequently also contribute to reducing the crying periods and to improving the quality of sleep, the general quality of life, the mood, the playfulness, the temperament and/or the happiness of the infants and young children.

COMPOSITIONS AND METHODS FOR ASCAROSIDE MODIFICATION OF MAMMALIAN MICROBIOTA
20220409650 · 2022-12-29 ·

Described herein are composition of ascarosides, methods of using them, and the like for inhibiting bacterial population growth or for altering the relative ratio of sub-populations of first and second bacteria in a mixed population of bacteria. The invention is particularly useful, for example, for modifying a microbiome of a patient (e.g., for treatment of gut microbiome dysfunction).