Patent classifications
A61P3/02
METHODS AND COMPOSITIONS FOR TREATING 25-HYDROXYVITAMIN D DEFICIENCY
A method of treating a cholecalciferol (VD) deficiency associated condition in a patient comprising administering a pharmacologically effective does of a pharmaceutical composition containing VD and one of glutathione (GSH) and a GSH precursor. A pharmaceutical composition for treating a cholecalciferol (VD) deficiency associated condition comprising a pharmacologically effective does of VD and one of glutathione (GSH) and a GSH precursor.
VITAMIN D FORMULATIONS
A pharmaceutical formulation, adapted for oral administration, wherein the pharmaceutical formulation comprises at least 1 000 IU, preferably of from 5 000 to 400 000 IU of a Vitamin D, per dosage form, and wherein the pharmaceutical formulation comprises, or consists of, an aqueous dispersion of micelles encapsulating said Vitamin D, and wherein the micelles are formed of, and essentially consist of, a tocopherol polyalkylene glycol such as D-?-tocopherol polyethylene glycol succinate.
VITAMIN D FORMULATIONS
A pharmaceutical formulation, adapted for oral administration, wherein the pharmaceutical formulation comprises at least 1 000 IU, preferably of from 5 000 to 400 000 IU of a Vitamin D, per dosage form, and wherein the pharmaceutical formulation comprises, or consists of, an aqueous dispersion of micelles encapsulating said Vitamin D, and wherein the micelles are formed of, and essentially consist of, a tocopherol polyalkylene glycol such as D-?-tocopherol polyethylene glycol succinate.
Reconstituted HDL formulation
The present invention relates to reconstituted high density lipoprotein (rHDL) formulations comprising an apolipoprotein, a lipid and a lyophilization stabilizer. Said formulations have reduced renal toxicity and good long-term stability, especially in lyophilized form.
Syringe stabilizer
A syringe stabilizing apparatus has a base and a syringe support. The syringe support is vertically disposed above the base, elevating a fluid-filled portion of an infusion set vertically above the base and orienting a delivery end of the fluid-filled portion upwardly relative to a horizontal plane to take advantage of a gravitational effect on a fluid during delivery of the fluid from the fluid-filled portion to a patient. The syringe support comprises a first retainer and a selectively actuated tube clamp. The first retainer has an opening in which a rigid portion of the infusion set is received and retained therein without further user intervention. The selectively actuated tube clamp is operatively aligned with the first retainer. A flexible tube extending from the rigid portion of the infusion set extends through the selectively actuated tube clamp.
COMPOSITION FOR MUSCLE ENHANCEMENT AND USE OF SAME
There is provided a novel ingredient that exhibits an exceptional effect for enhancing muscle using a fatty acid.
A composition for muscle enhancement, characterized in that the composition contains, as an active component, at least one selected from the group consisting of C13, C14, or C15 fatty acids and fatty acid esters that include these fatty acids. The fatty acid is preferably at least one selected from tridecanoic acid, tetradecanoic acid, or pentadecanoic acid. The composition for muscle enhancement is suitably used in the form of, inter alia, an oil and fat composition, a food or beverage, a supplement, or an animal feed.
Compositions comprising unsaturated fatty acids and nitric oxide releasing compounds and use thereof for enhancing cognitive and related functions
Compositions include arginine and one or more unsaturated fatty acids. Methods for using such compositions can enhance cognitive function, reduce or prevent a decline of social interaction, reduce or prevent age-related behavioral changes, increase trainability, maintain optimal brain function, facilitate learning and memory, reduce memory loss, retard brain aging, prevent or treat strokes, and/or prevent or treat dementia in an animal. Preferably, the compositions are food compositions useful for enhancing cognitive function in humans and companion animals.
Patches and methods for the transdermal delivery of a therapeutically effective amount of iron
Embodiments of the invention provide patches for the transdermal delivery of iron-containing compositions to an individual suffering from an iron deficiency. Many embodiments provide an iontophoretic patch for the transdermal delivery of a therapeutically effective amount of iron. The patch comprises an electrode and a reservoir containing a composition comprising ionic iron for the delivery of the therapeutically effective amount of iron. Various embodiments provide methods of using embodiments of the iontophoretic patch for delivering a therapeutically effective amount of iron to an individual suffering from one more forms of iron deficiency including iron deficiency anemia. Such methods can be used for treating and/or preventing the iron deficiency. The amount of delivered iron can be adjusted depending upon various treatment parameters such as patient weight and type and amount of iron deficiency.
Nutritive polypeptides and formulations thereof, and methods of production and use thereof
Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant microorganisms that make the polypeptides, vectors for expressing the polypeptides, methods of making the polypeptides using recombinant microorganisms, compositions and formulations that comprise the polypeptides, and methods of using the polypeptides, compositions and formulations.
Oral rehydration composition and methods thereof
An oral rehydration composition comprising the following: 1-glutamic acid in a range of about 0.01% to about 0.40% w/w and monosodium glutamate in a range of about 0.05% to about 0.80% w/w; about 1.50% w/w glucose monohydrate; about 0.20% w/w sodium chloride; about 0.15% w/w potassium chloride; about 0.35% w/w glycine; about 0.30% w/w trisodiumcitrate; about 0.15% w/w sodium dihydrogen phosphate; about 0.10% w/w xanthan gum; 85% Steviol Glycoside extract in a range of about 0.01% to about 0.03% w/w; about 0.20% w/w citric acid monohydrate; hydrolyzed whey in a range of about 0.15% to about 1.00% w/w; about 1.00% w/w hydrolyzed wheat; comprises cereals as a protein source; comprises enzyme co-factors; comprises a monosaccharide. The oral rehydration composition can be used on humans or animals that suffer from diarrhea.