The present invention relates to compositions comprising curcuminoids; in particular, compositions comprising curcuminoids that are highly water soluble. The present invention also relates to processes for providing such compositions and uses of such compositions.

Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, β-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.

The invention relates to compositions comprising EPA, MA and leucine for prevention and/or treatment of a disease or condition involving muscle decline or for improving muscle function.

The use of cholecalciferol is described as an active agent in the treatment of celiac disease, in the reduction of intestinal villous atrophy, and in the protection and regeneration of the intestinal epithelium. Also described are pharmaceutical compositions or food supplements, as well as foods for celiacs, including cholecalciferol and suitable excipients for use in the treatment of celiac disease, in the reduction of intestinal villous atrophy and in the protection and regeneration of the intestinal epithelium.

The use of cholecalciferol is described as an active agent in the treatment of celiac disease, in the reduction of intestinal villous atrophy, and in the protection and regeneration of the intestinal epithelium. Also described are pharmaceutical compositions or food supplements, as well as foods for celiacs, including cholecalciferol and suitable excipients for use in the treatment of celiac disease, in the reduction of intestinal villous atrophy and in the protection and regeneration of the intestinal epithelium.

A method of potentiating musculoskeletal effect of one or more anabolic amino acids in an individual in need thereof can include administering to the individual in need thereof a composition containing the one or more anabolic amino acids, the composition also containing one or more autophagy-inducing amino acids in a total amount effective for the composition to be at least neutral regarding autophagy. In another aspect, a method of overcoming one or more negative effects of one or more anabolic amino acids by preventing degenerative processes related to loss of autophagy can include administering to an individual in need thereof a composition containing the one or more anabolic amino acids, the composition further containing the one or more autophagy-inducing amino acids in a total amount effective for the composition to be at least neutral regarding autophagy.

A method of potentiating musculoskeletal effect of one or more anabolic amino acids in an individual in need thereof can include administering to the individual in need thereof a composition containing the one or more anabolic amino acids, the composition also containing one or more autophagy-inducing amino acids in a total amount effective for the composition to be at least neutral regarding autophagy. In another aspect, a method of overcoming one or more negative effects of one or more anabolic amino acids by preventing degenerative processes related to loss of autophagy can include administering to an individual in need thereof a composition containing the one or more anabolic amino acids, the composition further containing the one or more autophagy-inducing amino acids in a total amount effective for the composition to be at least neutral regarding autophagy.

The present invention provides the uses of 5-methyltetrahydrofolate and its composition. The 5-methyltetrahydrofolate or its composition is used to treat, relieve or prevent diseases or symptoms caused by acute alcohol intoxication and chronic alcohol intoxication. The injuries or diseases caused by the acute alcohol intoxication include: headaches caused by drinking, negative emotions or depression caused by drinking, and hangover symptoms after drinking. The injuries or diseases caused by the chronic alcohol intoxication include: alcoholic fatty liver, central nervous system (CNS) inflammation, etc.

Provided is the composition capable of effectively exerting an effect on a change in a hormone balance. A composition for inhibiting the decrease in endogenous testosterone and/or dihydrotestosterone, the composition comprising Cordyceps militaris derived from Samia cynthia ricini and/or its extract is prepared.

The present disclosure provides pharmaceutical formulations and methods for delivering a therapeutic, diagnostic, or imaging agent to CD206. In an aspect, the present disclosure encompasses a pharmaceutical formulation for administration. The pharmaceutical formulation comprises a recombinantly produced intrinsic factor (IF), wherein the IF has a glycosylation pattern that enables binding to CD206.