There is described a sheet-fed printing press (1000; 1000*) comprising at least two printing units (200; 200.1, 200.2; 200.1 *, 200.2*) located one after the other, each printing unit (200; 200.1, 200.2; 200.1 *, 200.2*) being adapted to carry out simultaneous recto-verso printing of the sheets (S) and including two printing cylinders (105, 106) cooperating with one another and forming a printing nip, the two printing cylinders (105, 106) each collecting ink patterns from at least two associated plate cylinders (15A, 15B, 16A, 16B) wherein the two printing cylinders (105, 106) are located one above the other such that the sheets (S) travel laterally through each printing unit (200; 200.1, 200.2; 200.1 *, 200.2*) from a first lateral side (201 a; 201 a*) located upstream of the printing nip to a second lateral side (201 b; 201 b*) located downstream of the printing nip, wherein a number of at least two sheet transfer elements (110, 120, 95) is provided downstream of the printing nip of a first one (200.1; 200.1 *) and upstream of the printing nip of a second one (200.2; 200.2*) of the at least two printing units (200.1, 200.2; 200.1 *, 200.2*) to transfer the sheets (S).

In some examples, an ink feed system for providing and feeding printing ink to an inking unit of an intaglio printing unit includes an inking device in the inking unit for inking a first inking unit cylinder. A provision device includes a storage receptacle with an ink reservoir of printing ink that is fed via an outlet and a line to the inking device. Furthermore, a wall of the storage receptacle encompassing the outlet can be heated and/or a metering device may be provided in the line path to support and/or effectuate delivery of the printing ink from the storage receptacle. On an output side, the metering device may provide a mass flow or volume flow that correlates with a working speed of the metering device via a defined relationship, and the metering device may be connected to a control device to control the working speed of the metering device.

An apparatus and method for use in generating a print job for an offset printing apparatus. The method comprising determining a print job to be printed on the offset printer comprises an odd number of separations, and in response to determining that the print job comprises an odd number of separations, alternating a print order of at least two separations between odd and even pages of the print job.

There is described a color control pattern (CP) for the optical measurement of colors printed on a sheet or web substrate (S) by means of a multicolor printing press, especially by means of a multicolor security printing press, which substrate (S) exhibits an effective printed region (EF) having a multicolor printed image comprising a plurality of juxtaposed colored areas (A-H) printed with a corresponding plurality of printing inks of different colors, wherein the color control pattern (CP) is located in a margin portion (Im) of the substrate (S) next to the effective printed region (EF). The color control pattern (CP) comprises one or more color control strips (a-d) extending transversely to a direction of transport (T) of the substrate (S), each color control strip (a-d) comprising a plurality of distinct color control fields (CF, CF.sub.A to CF.sub.H) consisting of printed fields of each relevant printing ink that is printed in the effective printed region (EF). The color control fields (CF, CF.sub.A to CF.sub.H) are coordinated to actual application of the relevant printing inks in the effective printed region (EF) and are positioned transversely to the direction of transport (T) of the substrate (S) at locations corresponding to actual positions where the relevant printing inks are applied in the effective printed region (EF).

The invention provides for the use of pharmaceutical compositions comprising a thiazolide in the stimulation of the immune system in a subject in need thereof, thereby preventing and/or treating viral diseases, cancer and diseases caused by intracellular protozoan infections

There is described an intaglio printing press comprising (i) a stationary machine frame (01) supporting an intaglio printing cylinder (07) and an impression cylinder (06) contacting the intaglio printing cylinder (07), (ii) an inking system (12, 13, 16) for inking the intaglio printing cylinder (07), which inking system (12, 13, 16) comprises an ink-collecting cylinder (12) designed to contact the intaglio printing cylinder (07) and at least one inking device (13, 16) for supplying ink to said ink-collecting cylinder (12), and (iii) at least a first mobile carriage (11) supporting the ink-collecting cylinder (12), which first mobile carriage (11) is adapted to be moved with respect to the stationary machine frame (01) between a working position where the ink-collecting cylinder (12) contacts the intaglio printing cylinder (07) and a retracted position where the ink-collecting cylinder (12) is retracted away from the intaglio printing cylinder (07). The axis of rotation of the ink-collecting cylinder (12) lies below a horizontal plane (P0) intersecting the axis of rotation of the intaglio printing cylinder (07) and a plane (P2) intersecting the axis of rotation of the ink-collecting cylinder (12) and the axis of rotation of the intaglio printing cylinder (07) forms, in the working position of the first mobile carriage (11), an acute angle () with respect to the horizontal plane (P0).

The invention provides for the use of pharmaceutical compositions comprising a thiazolide in the stimulation of the immune system in a subject in need thereof, thereby preventing and/or treating viral diseases, cancer and diseases caused by intracellular protozoan infections.

There is described a color control pattern (CP) for the optical measurement of colors printed on a sheet or web substrate (S) by means of a multicolor printing press, especially by means of a multicolor security printing press, which substrate (S) exhibits an effective printed region (EF) having a multicolor printed image comprising a plurality of juxtaposed colored areas (A-H) printed with a corresponding plurality of printing inks of different colors, wherein the color control pattern (CP) is located in a margin portion (Im) of the substrate (S) next to the effective printed region (EF). The color control pattern (CP) comprises one or more color control strips (a-d) extending transversely to a direction of transport (T) of the substrate (S), each color control strip (a-d) comprising a plurality of distinct color control fields (CF, CF.sub.A to CF.sub.H) consisting of printed fields of each relevant printing ink that is printed in the effective printed region (EF). The color control fields (CE, CF.sub.A to CF.sub.H) are coordinated to actual application of the relevant printing inks in the effective printed region (EF) and are positioned transversely to the direction of transport (T) of the substrate (S) at locations corresponding to actual positions where the relevant printing inks are applied in the effective printed region (EF).

A printing press (1) includes an obverse printing unit (12) configured to perform printing on an obverse surface of a sheet (3), a reverse printing unit (13) configured to perform printing on a reverse surface of the sheet (3), and an upstream-side obverse checking unit (41) configured to irradiate the obverse surface of the sheet (3) with visible light and performs a check based on reflected light and also perform a check different from the check using the visible light. It is therefore possible to execute a plurality of types of checks without using a dedicated checking machine other than the printing press (1).

It is especially described a control process for intaglio printing, in particular for printing paper securities, such as banknotes. This control process includes defining on an intaglio printing plate (80) control areas (150, 151-155; 170, 171-179) designed in such a manner as to allow in particular evaluation of effects of the printing pressure applied during printing of a substrate by means of the intaglio printing plate (80) and evaluation of effects of the ink coverage applied during inking of the intaglio printing plate (80), which control areas (150, 151-155; 170, 171-179) are engraved in a portion of the intaglio printing plate (80) in order to produce corresponding printed control zones (160, 161-165) on the substrate. The process further includes carrying out of measurements in the printed control zones allowing evaluation of the printing pressure applied during printing of the substrate as well as of the ink coverage applied during inking of the intaglio printing plate (80).