A sheet conveyance apparatus (1) is provided in a sheet-fed offset printing press (2) including a printing unit (11). The printing unit (11) includes an impression cylinder (13) configured to hold and convey a sheet (4) and a printing device (14) configured to print the sheet (4) held by the impression cylinder (13). The sheet conveyance apparatus (1) includes a transfer cylinder (28) configured to hand over the sheet (4) to the impression cylinder (13) of the printing unit (11), and a pressing cylinder (29) configured to press the sheet (4) held by the transfer cylinder (28) against an outer surface of the transfer cylinder (28). The pressing cylinder (29) can press the sheet (4) against the transfer cylinder (28), and sufficiently stretch it.

A sheet conveyance apparatus (1) is provided in a sheet-fed offset printing press (2) including a printing unit (11). The printing unit (11) includes an impression cylinder (13) configured to hold and convey a sheet (4) and a printing device (14) configured to print the sheet (4) held by the impression cylinder (13). The sheet conveyance apparatus (1) includes a transfer cylinder (28) configured to hand over the sheet (4) to the impression cylinder (13) of the printing unit (11), and a pressing cylinder (29) configured to press the sheet (4) held by the transfer cylinder (28) against an outer surface of the transfer cylinder (28). The pressing cylinder (29) can press the sheet (4) against the transfer cylinder (28), and sufficiently stretch it.

A medium support unit includes a support portion on which it is possible to set a medium in a setting direction that runs parallel to a support surface, and a friction member that is attached to the support portion, in which the friction member has an incision formation portion at a position that corresponds to a corner portion, and the incision formation portion that covers the corner portion positioned on an upstream side than the center in the setting direction has a first cover portion and a second cover portion positioned on a downstream side than the setting direction than the first cover portion, the first cover portion overlaps with the second cover portion such that an end portion of the first cover portion on the downstream side in the setting direction covers an end portion of the second cover portion on the upstream side in the setting direction.

The invention provides for the use of pharmaceutical compositions comprising a thiazolide in the stimulation of the immune system in a subject in need thereof, thereby preventing and/or treating viral diseases, cancer and diseases caused by intracellular protozoan infections

The invention provides for the use of pharmaceutical compositions comprising a thiazolide in the stimulation of the immune system in a subject in need thereof, thereby preventing and/or treating viral diseases, cancer and diseases caused by intracellular protozoan infections

A broadsheet newspaper printing press is provided including an image carrier carrying three images around in broadsheet newspaper format. The image carrier transfers the three images to a web. The broadsheet newspaper printing press also includes a folder for imparting a longitudinal fold to the web and cutting the web into broadsheet newspaper pages. The folder includes a cylinder cross-folding the broadsheet newspaper pages off center. A web offset broadsheet newspaper printing press also is provided. Methods are also provided.

A broadsheet newspaper printing press is provided including an image carrier carrying three images around in broadsheet newspaper format. The image carrier transfers the three images to a web. The broadsheet newspaper printing press also includes a folder for imparting a longitudinal fold to the web and cutting the web into broadsheet newspaper pages. The folder includes a cylinder cross-folding the broadsheet newspaper pages off center. A web offset broadsheet newspaper printing press also is provided. Methods are also provided.

A lithographic printing sleeve for mounting on a cylinder in a printing press is provided. The lithographic printing sleeve includes a tubular base layer for contacting and surrounding an outer circumference of the cylinder, a permanent tubular hydrophilic layer on an outer surface of the tubular base layer and a temporary hydrophobic layer on an outer surface of the tubular hydrophilic layer. A variable cutoff printing press is also provided.

A lithographic printing sleeve for mounting on a cylinder in a printing press is provided. The lithographic printing sleeve includes a tubular base layer for contacting and surrounding an outer circumference of the cylinder, a permanent tubular hydrophilic layer on an outer surface of the tubular base layer and a temporary hydrophobic layer on an outer surface of the tubular hydrophilic layer. A variable cutoff printing press is also provided.

An automated system and method of printing designs. The system and method can manage print content by application of programmable inks to selected areas in the packaging where frequently modified designs are printed. Such an approach allows the area to be precisely activated to correspond to the target pattern of the desired design and permanently change color. In some embodiments, any change in the text on the packaging/label would then only need to be translated into a corresponding UV or heat pattern, thereby avoiding the production of a new print cylinder to print the changed design. The proposed embodiments are effective in reducing downtime during print operations as well as expanding the capacity of the print apparatus to dynamically respond to changes in print designs.