The present disclosure discloses an expectorant compound, and specifically discloses compounds represented by formula I and formula II, pharmaceutically acceptable salts or tautomers thereof.

The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.

The invention provides compounds, compositions, methods, and kits for the treatment of neurogenic inflammation.

The present invention features processes for preparing compounds, such as (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)N(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1), useful for treating CFTR mediated diseases such as cystic fibrosis.

The present application discloses a Chinese herbal oral paste for conditioning phlegm-dampness constitution. The Chinese herbal oral paste includes the following raw material components: tangshen, prepared largehead atractylodes rhizome, prepared atractylodes rhizome, turmeric, unprocessed germinated barley, villous amomum fruit, coix seed, kelp, peach seed, tall gastrodia tuber, fuling, dried tangerine peel, seaweed, bitter apricot seed, cardamon fruit, perilla fruit, oriental waterplantain rhizome, ricepaperplant pith, Chinese waxgourd peel, kudzu vine root, unprocessed hawthorn fruit, milkvetch root, rice beans, lotus leaf, fortune eupatorium herb leaf, unprocessed cattail pollen, unprocessed rhubarb root and rhizome, inner membrane of chicken gizzard, white mustard seed, agastache rugosa, radish seed, xylitol, donkey-hide gelatin, and tortoise-plastron gelatin. The Chinese herbal oral paste of the present disclosure has a higher drug concentration and good taste, is particularly suitable for health preserving in winter and conditioning the phlegm-dampness constitution, will not create negative effects or harm to the human body at all, and is capable of achieving certain efficacy of strengthening physical health.

The present invention relates to bioavailable fill compositions containing one or more of a decongestant, an expectorant, an antitussive, an analgesic, and/or an antihistamine; capsules filled with the bioavailable fill compositions; and methods of making same.

A dibromobenzyl derivative with a structure shown as formula I, a stereoisomer or a pharmaceutically acceptable salt thereof and a preparation method and an application of the dibromobenzyl derivative are provided. The dibromobenzyl derivative or the stereoisomer thereof is superior in in-vivo pharmacokinetic stability and drug efficacy, and capable of being used for preparing respiratory drugs, in particular the apophlegmatic drugs. ##STR00001##

The present invention belongs to the field of medicine, relates to an inhaled preparation of isoglycyrrhizic acid or a salt thereof, and in particular relates to an inhaled preparation of magnesium isoglycyrrhizinate and the use thereof in preparing drugs for treating respiratory system diseases.

The present invention belongs to the field of medicine, relates to an inhaled preparation of isoglycyrrhizic acid or a salt thereof, and in particular relates to an inhaled preparation of magnesium isoglycyrrhizinate and the use thereof in preparing drugs for treating respiratory system diseases.

Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.