The present application relates to a method of treating an inflammatory skin condition by administering a pharmaceutical composition comprising a reduced dose of minocycline to a subject in need thereof, wherein said administration provides an effective plasma or interstitial fluid concentration of minocycline for treating the inflammatory skin condition.

The present invention relates generally to: a composition comprising or consisting of at least one avenantlrramide or an analogue thereof and 4-hydroxyacetophenone with an improved solubility; its cosmetic or medical use; the use of such composition N for the preparation of foods, food supplements, cosmetic, pharmaceutical or veterinary preparations; and foods, food supplements, cosmetic, pharmaceutical or veterinary perparations comprising such a composition. Finally, the present invention relates to 4-hydrox-yacetophenone for improving solutility of an avenantramide or an analogue thereof.

Provided herein are novel isotretinoin formulations that provide an enhanced targeted dermal delivery system for the drug isotretinoin with improved thermodynamic activity using no to a small level of ethanol relative to existing isotretinoin gel products, and methods for treatment of ichthyosis and other skin conditions using the same.

Provided herein are novel isotretinoin formulations that provide an enhanced targeted dermal delivery system for the drug isotretinoin with improved thermodynamic activity using no to a small level of ethanol relative to existing isotretinoin gel products, and methods for treatment of ichthyosis and other skin conditions using the same.

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. ##STR00001##
wherein the symbols in the formula are defined below: R.sup.1: e.g., a C1-C6 alkyl group; R.sup.2: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R.sup.3: e.g., a C1-C6 alkyl group.

Provided is a microorganism of the genus Epidermidibacterium belonging to the family Sporichthyaceae, or a culture thereof, or a composition for preventing, improving, or treating skin conditions or inflammatory diseases including the same.

Provided is a microorganism of the genus Epidermidibacterium belonging to the family Sporichthyaceae, or a culture thereof, or a composition for preventing, improving, or treating skin conditions or inflammatory diseases including the same.

A moisturizing lotion composition includes water. In addition, the moisturizing lotion composition includes propylene glycol having a concentration of 21.0 to 37.5 wt % of the moisturizing lotion composition. Further, the moisturizing lotion composition includes aloe vera having a concentration of 0.50 to 4.0 wt % of the moisturizing lotion composition. Still further, the moisturizing lotion composition includes vervain extract having a concentration of 0.50 to 4.0 wt % of the moisturizing lotion composition. Moreover, the moisturizing lotion composition includes willow bark extract having a concentration of 0.50 to 0.20 wt % of the moisturizing lotion composition. The moisturizing lotion composition also includes chamomilla recutita extract having a concentration of 0.05 to 0.40 wt % of the moisturizing lotion composition.

A moisturizing lotion composition includes water. In addition, the moisturizing lotion composition includes propylene glycol having a concentration of 21.0 to 37.5 wt % of the moisturizing lotion composition. Further, the moisturizing lotion composition includes aloe vera having a concentration of 0.50 to 4.0 wt % of the moisturizing lotion composition. Still further, the moisturizing lotion composition includes vervain extract having a concentration of 0.50 to 4.0 wt % of the moisturizing lotion composition. Moreover, the moisturizing lotion composition includes willow bark extract having a concentration of 0.50 to 0.20 wt % of the moisturizing lotion composition. The moisturizing lotion composition also includes chamomilla recutita extract having a concentration of 0.05 to 0.40 wt % of the moisturizing lotion composition.

The present invention relates generally to a composition or an oat extract comprising at least one avenanthramide compound or an analogue thereof and at least one β-glucan compound at predetermined ratios and having a low salt content. In addition, the present invention relates to a method for preparing such an oat extract, an oat extract obtained by said method, and the use of said composition or oat extract for the preparation of foods, food supplements, cosmetic, pharmaceutical or veterinary preparations. Finally, the present invention relates to foods, food supplements, cosmetics, pharmaceuticals or veterinary preparations comprising said composition or oat extract.