Disclosed herein are compounds that are effective for treatment of various disease states. Dosing includes both single administration and regimens of cycling dosages.

The invention relates to a method for producing free powder particles of polyamide, impregnated with at least one cosmetic or pharmaceutical agent. The present invention also relates to free powder particles of polyamide having a content of at least 25% by weight of a cosmetic or pharmaceutical agent other than water, to the use of said particles in a cosmetic, pharmaceutical or perfumery products, and to compositions containing such particles.

The present invention concerns a topical, cosmetic or pharmaceutical preparation containing a combination of 3 or 4 solar filters comprising:—one or two UVA filters to obtain a critical wavelength>370 nm, chosen from among: (i)—5,6,5,6-tetraphenyl-3, 3′-(1,4-phenylene)-bis[1,2,4]triazine; (ii) 1,1′-(1,4-piperazinediyl)bis[1-[2-[4-(diethylamino)-2-hydroxybenzoyl]phenyl]-methanone; (iii)—Butyl Methoxydibenzoylmethane (BMDBM), in a quantity less than 2% by weight with regard to the total weight of said composition; (iv)—Hexyl-[4-(diethylamino)-2-hydroxybenzoyl]benzoate, -2,4-Bis[4-(2-ethyl-hexyloxy)-2-hydroxyphenyl]-6-(4-methoxyphenyl)-1,3,5-triazine=(BEMT), —one or two filters chosen from among UVB filters, except octocrylene, PABA and ethylhexyl methoxycinnamate, said composition also containing a pharmaceutically or cosmetically acceptable excipient.

Compositions comprising emu oil as a vehicle for the delivery of other active ingredients for the treatment of cosmetic and other skin imperfections such as acne, wrinkles, and hair loss are disclosed. Methods of treating cosmetic and other skin imperfections using the compositions are also disclosed.

Compositions and methods are provided herein for regenerating and repairing damaged or aged tissue or organs using nonviable lethally irradiated or lyophilized pluripotent stem cells. In one aspect, the compositions and methods described herein provide anti-aging benefits to the skin by increasing the hydration reducing fine lines, wrinkles, and pores of the skin. Compositions and methods are also provided for promoting wound healing using lyophilized pluripotent stem cell powder. A method is provided for inducing cardiac muscle regeneration in a primate comprising delivering nonviable lethally irradiated pluripotent stem cells to damaged or aged areas of the heart. The compositions and methods include nonviable lethally irradiated or lyophilized pluripotent stem cells. In one aspect, the compositions and methods utilize nonviable pluripotent stem cells in the form of a powder, such as lyophilized stem cells.

Disclosed is a use of Combretum micranthum extract in cosmetics. Processes such as a solvent extraction method and a chromatographic method are specifically used, it is found that a Combretum micranthum plant or its extract has the effects of moisturizing, anti-inflammatory, post-sun repair, repair of skin barrier, repair of UV-induced DNA damage, whitening, fading spots and anti-glycation and the like. The prepared Combretum micranthum extract can be added into cosmetics as an active ingredient thereof. The cosmetic or drug containing the Combretum micranthum extract has the efficacies of moisturizing, anti-inflammatory, post-sun repair, repair of skin barrier, repair of UV-induced DNA damage, whitening, anti-freckle and resisting saccharification and the like, thereby achieving the effect of skin care and beauty.

The present invention relates to methods and compositions for treatment and alleviation of diseases. Particularly, the invention provides compositions comprising very long chain fatty acids for use in treatment, such as of subjects having a deficient or abnormal level of VLCFAs present in specific tissue which play a role in the disease. Particularly, the invention provides methods and compositions for treatment of subjects having a reduced ability for endogenic synthesis of fatty acids.

Provided are oxygenated cannabis skin therapy compositions, and methods for preparing the compositions by ozonating coconut oil, extracting medicinal/recreational cannabis into coconut oil to yield a cannabis infused coconut oil, and combining the ozonated coconut oil with the cannabis infused coconut oil to yield the skin therapy compositions.

Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation.

Novel polyphenol compositions and methods for the treatment and prevention of radiation dermatitis, eczema, thermal burns, wounds, and certain cancers. The disclosure also relates to methods for the preparation of polyphenol compositions including flavonoid compositions.