The present invention relates to a device for replacing the printing roller in a printing unit, in particular for in line rotary flexographic machines.

An apparatus for replacing printing sleeves which comprises a handling device which can be removably engaged with a printing sleeve and a movement robot for moving the handling device; the handling device comprises a supporting frame and a self-centering grip clamp which is able to translate on command, with respect to the supporting frame, along a movement direction that is substantially parallel to the axis of the supporting rod, between an advanced working position and a retracted working position; the grip clamp has engagement elements which are movable on command between an inactive position and an active position, in which they are radially spaced apart from the axis of the supporting rod, in order to allow their engagement with the internal surface of the printing sleeve.