The present invention aims to provide a composition for sleep improvement, which contains a highly safe substance as an active ingredient, and a method of improving sleep. The present invention relates to, for example, a composition for sleep improvement, which contains L-ergothioneine or a salt thereof as an active ingredient.

The present invention aims to provide a composition for sleep improvement, which contains a highly safe substance as an active ingredient, and a method of improving sleep. The present invention relates to, for example, a composition for sleep improvement, which contains L-ergothioneine or a salt thereof as an active ingredient.

A nitrogen-containing ring derivative regulator, a preparation method therefor and use thereof. In particular, the present invention relates to a compound as represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and use thereof as a G protein-coupled receptor regulator in the treatment or prevention of central nervous system diseases and/or mental diseases.

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The disclosure relates to a traditional Chinese medicine composition and product for improving sleep by balancing yin and yang, a method for making the same and use thereof, and belongs to the technical field of traditional Chinese medicine. The disclosure provides a traditional Chinese medicine composition for improving sleep by balancing yin and yang, which has reasonable compatibility of all herbal medicines, nourishes yin to suppress yang, tonifies blood and promotes blood, regulates qi and soothes the nerves, and has the functions of reconciling yin and yang and balancing qi and blood. The composition may fundamentally improve sleep quality, with an effective rate of 100%. At the same time, all the medicines in the prescription are raw materials of medicine food homology, which are safe and effective, not cause side effects and mental dependence on the human body, and may be taken for a long time.

The disclosure relates to a traditional Chinese medicine composition and product for improving sleep by balancing yin and yang, a method for making the same and use thereof, and belongs to the technical field of traditional Chinese medicine. The disclosure provides a traditional Chinese medicine composition for improving sleep by balancing yin and yang, which has reasonable compatibility of all herbal medicines, nourishes yin to suppress yang, tonifies blood and promotes blood, regulates qi and soothes the nerves, and has the functions of reconciling yin and yang and balancing qi and blood. The composition may fundamentally improve sleep quality, with an effective rate of 100%. At the same time, all the medicines in the prescription are raw materials of medicine food homology, which are safe and effective, not cause side effects and mental dependence on the human body, and may be taken for a long time.

The present invention aims to provide an agent for preventing or ameliorating stress disorders, which agent is highly safe and effective, causes less side effects, and can be continuously used for a long time.

One embodiment of the present invention is an agent for preventing or ameliorating stress disorders comprising, as an active ingredient, a lactic acid bacterium Lactobacillus delbrueckii subspecies lactis or a lactic acid bacterium-derived ingredient therefrom.

Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed. ##STR00001##

The present invention relates to compositions and methods for treating fat deposit accumulation in a subject. The invention provides a non-surgical method for reducing fat deposits comprising administering an effective amount of a fat-lysing concentration of one or more of cholate and chenodeoxycholate in a pharmaceutically acceptable formulation to the subject in need thereof.

The present disclosure concerns the use of an inhibitor of actin remodeling modulator thereof, for the preparation of a medicament for treating memory deterioration caused by sleep deprivation.

The present disclosure concerns the use of an inhibitor of actin remodeling modulator thereof, for the preparation of a medicament for treating memory deterioration caused by sleep deprivation.