A device for irrigation of an oral cavity in a patient includes a suction element configured to be disposed in the oral cavity and configured to suction a fluid out of the oral cavity. The suction element also has one or more irrigation outlets configured to irrigate the oral cavity with the fluid. A suction line is fluidly coupled with the suction element and is configured to be fluidly coupled with a vacuum source. An irrigation line is fluidly coupled with the one or more irrigation outlets and is fluidly coupled with a source of the fluid.

The invention provides compositions that include isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains and genetically engineered LDH-deficient bacterial strains, which can be used to whiten teeth and treat periodontal disease.

The invention provides compounds for use in inhibiting a microbial alternative oxidase (AOX) and/or cytochrome bc.sub.1 complex. The invention extends to the use of such inhibitors in agrochemicals and in pharmaceuticals, for treating microbial infections, including fungal infections.

An aqueous solution composition containing a hydrolysate or a hydrolytic condensate of an organosilicon compound of formula (1), or both the hydrolysate and the hydrolytic condensate:

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wherein R.sup.1 and R.sup.2 are each independently an alkyl group having 1 to 10 carbon atoms or an aryl group having 6 to 10 carbon atoms, R.sup.3 is an alkyl group having 12 to 24 carbon atoms, R.sup.4 and R.sup.5 are each independently an alkyl group having 1 to 6 carbon atoms, X is a halogen atom, m is an integer of 4 to 20, and n is an integer of 1 to 3.

Provided is a modified bacteriophage capable of infecting a target bacterium, which bacteriophage includes an α/β small acid-soluble spore protein (SASP) gene encoding a SASP which is toxic to the target bacterium, wherein the SASP gene is under the control of a constitutive promoter which is foreign to the bacteriophage and the SASP gene.

The subject invention provides materials methods for reducing infections in subjects. The materials methods utilize chlorhexidine, which has been found to be surprisingly non-toxic. The lack of toxicity facilitates the use of chlorhexidine in contexts that were not previously thought to be possible.

Dental devices are described that include isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains and genetically engineered LDH-deficient bacterial strains, which can be used to whiten teeth and treat periodontal disease.

This invention relates to oral care compositions comprising arginine or lysine, zinc citrate and zinc oxide, and a fluoride source, as well as to methods of using and of making these compositions.

Processes and systems for lessening human spread of coronaviruses can include use of a disinfectants and/or rinses that utilize contact times of up to 2 minutes or less than 2 minutes and also more than 20 seconds. Some embodiments can include gargling a rinse having at least one disinfectant as an active ingredient for up to 2 minutes or for a time period of less than 2 minutes. Other embodiments can include performing a naso-rinse for up to 2 minutes or a time period of less than 2 minutes and also more than 20 seconds with rinse fluid having at least one disinfectant.

The present invention provides pharmaceutical compositions comprising an antiseptic and a steroid, useful for treating a clinical symptom in a patient's airway (e.g., nose, lung, and sinus), wherein a gel containing the antiseptic is formed in situ upon instillation of the compositions onto a body cavity of a subject, as well as methods for using the same.