There is a method for producing a hop processed product. The hop processed product is for use in foodstuff for anti-adipocyte differentiation or for antioxidation. It contains 50% by weight or more, preferably 60% by weight or more, and more preferably 70% by weight or more, of hop flowers (EM) showing hues satisfying that a value of a* is less than −0.5 in accordance with a CIE Lab color space, and preferably that a value of h is 90° or more in accordance with a CIE Lch color space. The hop processed product of the present invention has excellent action of anti-adipocyte differentiation or antioxidant action, so that the hop processed product can be expected to have effects in, for example, “anti-metabolic syndrome,” “anti-aging,” “anti-obesity,” and the like.

A combination that includes: a flavonoid, for example in an amount from about 0.1 g to about 1.5 g; and one or more of: ascorbic acid, ascorbate, or a combination thereof, for example in an amount from about 0.2 g to about 2.0 g; N-acetyl cysteine, for example in an amount from about 0.10 g to about 1.2 g; alpha-lipoic acid, for example in an amount from about 0.05 g to about 0.60 g; and at least one carotenoid, for example in an amount from about 1 mg to about 50 mg. The combination may be used to mitigate or prevent nuclear DNA damage, mitochondrial DNA damage, lipid peroxidation, protein carbonylation, or any combination thereof in a subject caused by oxidative stress.

Some embodiments disclosed herein include a method for increasing an expression level of a gene. The methods can include identifying a human subject having an increased expression level of COX1; and administering to the human subject an effective amount of a nitroxide antioxidant, whereby expression level of the gene is decreased.

Some embodiments disclosed herein include a method for increasing an expression level of a gene. The methods can include identifying a human subject having an increased expression level of COX1; and administering to the human subject an effective amount of a nitroxide antioxidant, whereby expression level of the gene is decreased.

The invention relates to carrier complexes and methods for delivering molecules to cells. The carrier complexes comprises a molecule and an aromatic cationic peptide in accordance with the invention. In one embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a carrier complex. In another embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a molecule and an aromatic cationic peptide.

The present invention relates to compounds having a lipid affinity of less than 15% by weight of the compound (such as a log P of −0.75 or less) for use in targeting mitochondria to reduce, inhibit or prevent the formation of mitochondrial reactive oxygen species and for use in treating or preventing a pathological condition associated with increased levels of mitochondrial reactive oxygen species, and for non-therapeutic uses, such as enhancing sports performance and reducing, inhibiting or preventing the formation of mitochondrial reactive oxygen species during exercise, resulting in maintenance of muscle strength and/or a reduction in muscle fatigue, and associated methods. The present invention also relates to extracts and compositions comprising compounds having a lipid affinity of less than 15% (such as a log P of −0.75 or less) for the same uses.

There are disclosed an antioxidant agent, an antisaccharification agent, a neurite outgrowth promoting agent, and a cognitive function improving agent, which contain propolis and a ginkgo leaf extract as active ingredients.

A botanical extract that exhibits antioxidant activity, wherein the botanical extract is at least an extract from the genus Anacardium.

A botanical extract that exhibits antioxidant activity, wherein the botanical extract is at least an extract from the genus Anacardium.

Provided herein are methods and compositions for maintaining and/or increasing vitamin C in a cell or organism. The methods and compositions are based, in part, on the synergistic effect of ergothioneine, or a derivative thereof, on vitamin C levels in cells or organisms.