This disclosure relates to anti-microbial sanitizer compositions and methods of making the same. The sanitizer compositions described herein are comprised of benzalkonium chloride, coconut oil, palm kernel oil, water, dihydroxypropyl PEG-5, linoleammonium chloride, and glycereth-2 cocoate. To forming the sanitizer compositions discussed herein, water is mixed with benzalkonium chloride to form a first mixture. This first mixture is then mixed with coconut oil and palm kernel oil to form a second mixture, which is subsequently heated to at least 100° F. After heating, the second mixture is mixed with dihydroxypropyl PEG-5 to form a third mixture, which is then settled while the temperature is maintained at or above 100° F., Thereafter, the third mixture is cooled to room temperature, and mixed with linoleammonium chloride and glycereth-2 cocoate to form the sanitizer composition.

A hand sanitizing composition and a method of manufacture, wherein the composition includes a solvent from about 78% to about 96% by weight sufficient to operate as a carrier and solvent. The composition includes tetrasodium EDTA and/or Sodium Citrate from about 0.01% to about 1% by weight to operate as a buffer, stabilizer and chelating agent. The composition includes a humectant selected from the group of humectants consisting of: Cetyl Alcohol, Ceteryl Alcohol, and Steryl Alcohol from about 1.5% to about 5.5% by weight to emulsify, thicken and lubricate. The composition includes an emollient from about 0.1% to about 3.2% by weight and an antioxidant vitamin from about 0.01% to about 1% by weight. The composition includes a soothing agent in a therapeutically significant amount and a conditioner.

Antimicrobial compositions are described comprising a least one biguanide compound and at least one hydrocarbon surfactant comprising a saturated or unsaturated C.sub.2-C.sub.4 diol moiety and optionally further comprising alkoxy groups. In some embodiments, the composition further comprises an aqueous or hydrophilic liquid carrier. In favored embodiments, the diol surfactant is present in an amount such that the antimicrobial activity of the biguanide antimicrobial compound is improved. Also described are articles comprising the described antimicrobial composition and methods of use of the antimicrobial composition.

An antiseptic composition for use as a topical skin sanitizer or as a surface disinfectant includes Populus tremuloides Bark Extract and/or Ribes Nigum Fruit Extract in an amount of from about 0.1 to about 50 weight percent effective as a broad spectrum antiseptic and antimicrobial agent. The composition includes an aqueous medium and/or one or more oils. The amount of the aqueous medium is from 45 to about 95 weight percent. The amount of oils is from 0.03 to about 50 weight percent. The composition may also include up to about 1 weight percent of one or more soothing agents; up to about 5 weight percent of one or more thickeners; and up to about 38 weight percent of one or more emulsifiers. The composition does not contain alcohols, chlorinated compounds, iodine, or phenols.

Described herein are single-phase multi-component compositions and methods for their use reducing the viral load of infectious viruses on host organisms, including but not limited to Influenza A, Rhinovirus Type 14, Adenovirus Type 5, Herpes Simplex Virus Type 1, Herpes Simplex Virus Type 2, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2; COVID-19 virus), Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), and Human coronavirus 229E. The compositions described herein comprise a combination of an oxidative compound and a buffering system. The methods of use of these compositions as antiviral agents when applied to the oral, nasal, ocular, aural, anal, and urogenital cavities are described. Data shows the compositions to be effective in reducing influenza A and the human coronaviruses. In that regard, the single-phase multi-component compositions and methods for its antiviral use disclosed herein may be offer a single, effective product to combat multiple, concurrent pandemics.

Topical sanitizers including alcohol-based gels, alcohol-based foams, alcohol-free foams, liquid soaps, alcohol-based wipes, and alcohol-based sprays include avenanthramides, which is an active component of oats that is beneficial to the skin. The concentration of avenanthramides can be substantially less when considering the use profile of the person using the sanitizers. Many healthcare workers sanitize their hands dozens of times a day. An effective dose of avenanthramides can be delivered to the skin even when the concentration in avenanthramides is relatively low due to the repeated application of the sanitizers during the day. In addition, a lower concentration of avenanthramides may be used to maintain healthy skin compared to a higher concentration that may be used to repair damaged skin. Minimum concentrations of avenanthramides in one or more topical sanitizers can be determined according to the use profile and the target amount of avenanthramides to deliver via the topical sanitizers.

A portable casing is adapted to retain sanitary products. The portable casing has a retaining tray that is adapted be slid from the housing of the portable casing to permit sanitary products to be placed within the storage area. The retaining tray has a cut-out region that permits easy access to the sanitary products through a slot boated in a side of the portable casing.

A valve structuring designed for use in all water installations, water inlets for houses, kitchen installations and embedded shower filters as a stop valve, in the areas to perform on-off control, in faucets with the purpose of providing water savings and to use in domestic and industrial type kitchen faucets as a stop valve. The valve is designed for use as an on-off valve in air installations that operate with air.

The invention relates to 10H-benzo[g]pteridine-2,4-dione derivatives, to the production thereof, and to the use thereof.

This invention is a method of eliminating the number of microorganisms on the surface of skin, hair or nails, by contacting these surfaces with a water stable, antimicrobial silanol quaternary ammonium compounds (SQACs) and the trisilanol, polysiloxanol and water soluble polysiloxane derivatives thereof. The stabilizing agent is selected from a list of volatile, antimicrobial, naturally occurring, renewable phytochemical essential oils and extracts that easily form crystal clear microemulsions when water is added to the concentrated SQAC/essential oil mixture. These non-foaming oil in water microemulsions have excellent long term storage stability, are freeze/thaw stable, remain very low in viscosity and do not phase separate or precipitate for many months. Many of the essential oils found to be useful in this process are non-toxic food additives and have pleasant scents, have low flammability yet are volatile enough to evaporate upon cure down of the SQAC, thereby resulting in a higher concentration of SQAC in the cured, antimicrobial film. Economically shippable concentrations of the stabilized SQACs can be further diluted with water to application concentrations without loosing any of their stabilizing properties and remain storage stable at these lower concentrations indefinitely. In particular, the invention relates to the use of such viscosity controlled aqueous dilutions cured as durable antimicrobial coatings for human or animal skin that covalently bond to the skin, remain active through many washings and reduce or eliminate bacteria, viruses and fungi for days.