The invention relates to a dermatological composition comprising at least one polar extract of an alga of the Skeletonema genus or a photosensitizer derived therefrom, for the treatment of acne or bacterial infections; as well as a process for decontaminating a surface using a polar extract of an alga of the Skeletonema genus or a photosensitizer derived therefrom.

The present disclosure generally relates to compositions comprising unique combinations of cannabinoids, antioxidants, and cofactors. The present disclosure also provides methods of making the compositions and methods for using the compositions for the treatment of mitochondrial ATP deficit disorders.

The present invention relates to an essential oil of Satureja montana comprising more than 60% by weight of geraniol and more than 5% by weight of trans-β-caryophyllene, in particular of Satureja montana L. ssp. variegata. The present invention also relates to the cosmetic use of an essential oil of Satureja montana comprising more than 60% by weight of geraniol and more than 5% by weight of trans-β-caryophyllene, in particular of Satureja montana L. ssp. variegata, for treating greasy skin and/or preventing greasy or greasy-prone skin and/or the associated aesthetic skin defects. The invention also relates to a cosmetic composition comprising said oil, to a non-therapeutic cosmetic care and/or cleansing treatment process for greasy skin, and also to said essential oil as a dermatological agent.

Methods of treating aging related skin changes and of increasing skin thickness with topical administration of N-acyldipeptide derivatives are described. Compositions comprising N-acyldipeptide derivatives, are therapeutically effective for increasing skin thickness, and for treating extrinsic and intrinsic aging and aging related skin changes, such as fine lines, wrinkles, photoaging, hyperpigmentation, laxity, age spots, lentigines, mottled skin, and cellulite.

The present invention generally relates to skin care and, in particular, to systems and methods for treating and/or preventing acne. Acne is believed to be caused by a combination of factors, including Propionibacterium acnes bacteria, excess sebum production, and inflammation from the immune response (e.g., in response to P. acnes). Certain aspects of the invention are thus directed to one or more compositions that collectively target these factors, although it should be understood that a single composition may target more than one factor at a time. For instance, in one set of embodiments, a treatment may include a first composition that cleans the skin, a second composition that contains growth inhibitor of P. acnes (e.g., for use during the day), and a third composition that inhibits sebum production (e.g., for use during the night). One or more of these may contain other components, such as anti-inflammatory agents, moisturizers, topical anti-microbial agents (e.g., salicylic acid), or the like. Other aspects are generally directed to methods of making or use of such compositions, kits including such compositions, or the like.

A pharmacological composition for the treatment of bacterial and protozoal infections in a patient. The preferred pharmacological composition comprises a pharmaceutical carrier and an active composition selected from the group consisting of: a) an amount of sodium oxalate and an amount of oxalic acid, b) an amount of sodium citrate and an amount of citric acid, or c) mixtures of a) and b). The amounts and weight ratios of a) the sodium oxalate and oxalic acid, and b) the sodium citrate and citric acid in the active composition are such as to produce a safe and effective pharmacological composition. Sodium salts of other carboxylic acids may be used. The invention also relates to the method of using the pharmacological composition for the safe and effective treatment of bacterial infections, protozoal infections, lice and dermatological diseases.

Provided are a biological polysaccharide having the effect of preventing and treating acne and/or steroid-dependent dermatitis and the use thereof. Specifically, provided is the use of β-glucan for preparing a formulation or composition, wherein the formulation or composition is used in the prevention and/or treatment of acne and/or steroid-dependent dermatitis. The β-glucan has the effects of significantly relieving and improving acne and/or steroid-dependent dermatitis, effectively controlling the occurrence of acne and/or steroid-dependent dermatitis, accelerating the healing and/or regression of acne and/or steroid-dependent dermatitis.

Disclosed herein are methods for preventing acne in a patient comprising administering topically to the patient a composition effective to induce sebocyte differentiation. Also disclosed herein are methods of preventing acne in a patient comprising administering topically to the patient a composition effective to reduce insulin-induced lipoxygenase (LOX) activity and/or inflammatory processes. Also disclosed herein are methods of preventing a disease, condition, or disorder characterized by alteration of sebocyte differentiation, comprising administering topically to a patient a composition effective to induce sebocyte differentiation. The described methods can include administering a composition that includes a therapeutically effective amount of a PPARγ modulator, and a pharmaceutically acceptable excipient.

This invention relates to an external agent for normalizing sebaceous glands, the external agent comprising at least one member selected from the group consisting of cells of lactic acid bacteria belonging to the genus Enterococcus and cell components thereof, or a component that is extracted from cells of lactic acid bacteria belonging to the genus Enterococcus and that is soluble in ethyl acetate.

A method for reducing skin inflammation or reducing sebum production from sebaceous glands is disclosed. The method can include topically applying to skin in need thereof a composition that includes Psidium guajava fruit extract, wherein topical application of the composition reduces skin inflammation or reduces sebum production from sebaceous glands.