A Macadamia integrifolia whitening extract and a preparation method thereof are disclosed. The preparation method includes: S1: carrying out a hot extraction on a crushed Macadamia integrifolia green peel using an ethanol solution as an extraction solvent to obtain a crude green peel extract; then enzymatically treating the crude green peel extract using a snailase to obtain a enzymatic hydrolysate; finally extracting the enzymatic hydrolysate using a petroleum ether, and taking an aqueous phase to obtain a green peel extract; S2: carrying out a hot extraction on crushed Sichuan lovase rhizome decoction pieces using an ethanol solution as an extraction solvent to obtain a Sichuan lovase rhizome extract; S3: dispersing the green peel extract and the Sichuan lovase rhizome extract in water to obtain a whitening extract.

A method of topically applying a composition to skin is disclosed. The composition can include an acai berry fruit extract, water, glycerin, caprylic/capric triglyceride, cetyl alcohol, glyceryl stearate, dimethicone, tocopheryl acetate, carbomer, and citric acid.

A method of topically applying a composition to skin is disclosed. The composition can include an acai berry fruit extract, water, glycerin, caprylic/capric triglyceride, cetyl alcohol, glyceryl stearate, dimethicone, tocopheryl acetate, carbomer, and citric acid.

Disclosed herein are compounds that may be specific to PPAR and/or EGF receptors, and methods of making and using same.

Disclosed herein are compounds that may be specific to PPAR and/or EGF receptors, and methods of making and using same.

Described herein is a nanofibre matrix comprising 100% natural biopolymers selected from polysaccharides and/or proteins with optional functional ingredients for use as cosmetic products. More specifically, nanofibre matrix manufactured by electrospinning methods comprising a dry sheet without containing any preservatives, surfactants, solvents and crosslinkers. To use nanofibre cosmetic products, simply wet skin and then apply the nanofibre to skin. Functional ingredients may be optionally incorporated within the nanofibre matrix during electrospinning to provide different cosmetic effects. Functional ingredients offer skin benefits such as moisturizing, anti-ageing, wrinkle reduction, brightening, antioxidant and acne treatment. Functional ingredients can be essential oil where it is incorporated into nanofibre matrix to provide scent effect to cosmetic products. Functional ingredients can also be natural dye where it is incorporated in nanofibre matrix to make coloured nanofibres. Coloured nanofibres can be used for makeup products such as blush, eye shadow, eyebrow, nail polish, lipstick, contouring and hair dye product. The nanofibre matrix comprising 100% natural biopolymers with or without functional ingredients can be processed to assorted shapes or easily cut by consumers for using on different areas of skin for different purposes.

Described herein is a nanofibre matrix comprising 100% natural biopolymers selected from polysaccharides and/or proteins with optional functional ingredients for use as cosmetic products. More specifically, nanofibre matrix manufactured by electrospinning methods comprising a dry sheet without containing any preservatives, surfactants, solvents and crosslinkers. To use nanofibre cosmetic products, simply wet skin and then apply the nanofibre to skin. Functional ingredients may be optionally incorporated within the nanofibre matrix during electrospinning to provide different cosmetic effects. Functional ingredients offer skin benefits such as moisturizing, anti-ageing, wrinkle reduction, brightening, antioxidant and acne treatment. Functional ingredients can be essential oil where it is incorporated into nanofibre matrix to provide scent effect to cosmetic products. Functional ingredients can also be natural dye where it is incorporated in nanofibre matrix to make coloured nanofibres. Coloured nanofibres can be used for makeup products such as blush, eye shadow, eyebrow, nail polish, lipstick, contouring and hair dye product. The nanofibre matrix comprising 100% natural biopolymers with or without functional ingredients can be processed to assorted shapes or easily cut by consumers for using on different areas of skin for different purposes.

An enhanced alkaline pigment lightening suspension formulation for fading of unwanted cosmetic tattoos is proposed. The improved formulation of the claimed chemical tattoo lightening suspension is additionally complemented with a suggested neutralizing technique. The proposed innovative method includes the application of alkaline solution followed by an acid solution to reduce side effects. Additionally, a unique method of administration of the post-removal skin rehabilitation is proposed. The treatment is proven effective in scar reduction and consists of the administration of percutaneous collagen induction treatments following the aforementioned tattoo lightening treatments.

An enhanced alkaline pigment lightening suspension formulation for fading of unwanted cosmetic tattoos is proposed. The improved formulation of the claimed chemical tattoo lightening suspension is additionally complemented with a suggested neutralizing technique. The proposed innovative method includes the application of alkaline solution followed by an acid solution to reduce side effects. Additionally, a unique method of administration of the post-removal skin rehabilitation is proposed. The treatment is proven effective in scar reduction and consists of the administration of percutaneous collagen induction treatments following the aforementioned tattoo lightening treatments.

Provided are compounds of formula (I), (Ia), (Ib), and (Ic), and pharmaceutically and/or cosmeceutically acceptable salts thereof. Additionally provided are pharmaceutical and/or cosmeceutical compositions and formulations, comprising the compounds and/or salts thereof, therapeutic and/or cosmetic methods using same for modulating (e.g., inhibiting) CREB binding protein (CBP)/β-catenin mediated signaling in treating skin related diseases, conditions or disorders (e.g., dermatitis, psoriasis, scarring, alopecia, etc.) mediated by aberrant CBP/β-catenin signaling, and cosmetic methods for treating skin conditions (e.g., aging, etc.) mediated by aberrant CBP/β-catenin signaling.