A topical skincare composition that includes (A) a reducing sugar, (B) an aromatic sulfonate having a topological polar surface area (tPSA) of less than 100 Å.sup.2, and (C) a carrier. A method for adjusting color appearance (e.g., hue angle, lightness, saturation) of skin, which involves applying the topical skincare composition onto the skin is also specified. The topical skincare composition can provide a deep, rich, long lasting sunless tan with aesthetically pleasing red/bronze tone when applied onto the skin.

A topical skincare composition that includes (A) a reducing sugar, (B) an optionally substituted C.sub.8-12 alkyl sulfonate, and (C) a carrier. The composition may further include an aromatic sulfonate. A method for enhancing color appearance (e.g., hue angle, lightness, saturation) of skin, which involves applying the topical skincare composition onto the skin is also specified. The topical skincare composition can provide a deep, rich, long lasting artificial tan with customizable hue preservation or adjustment when applied onto the skin.

A topical skincare composition that includes (A) a reducing sugar, (B) an optionally substituted C.sub.8-12 alkyl sulfonate, and (C) a carrier. The composition may further include an aromatic sulfonate. A method for enhancing color appearance (e.g., hue angle, lightness, saturation) of skin, which involves applying the topical skincare composition onto the skin is also specified. The topical skincare composition can provide a deep, rich, long lasting artificial tan with customizable hue preservation or adjustment when applied onto the skin.

The present disclosure relates method of tanning a person including applying a moisturizer to an applicator and applying a tanning solution to the applicator. The moisturizer and the tanning solution are applied to the applicator in separate steps. The applicator is then contacted onto the skin of a person to apply the moisturizer and tanning solution.

The present disclosure relates method of tanning a person including applying a moisturizer to an applicator and applying a tanning solution to the applicator. The moisturizer and the tanning solution are applied to the applicator in separate steps. The applicator is then contacted onto the skin of a person to apply the moisturizer and tanning solution.

Short tri- and tetrapeptides according to the following Formula I Ar(CH2).sub.mX.sup.1—X.sup.2—CO—X.sup.3—X.sup.4—X.sup.5-(Trp).sub.n-NX.sup.6R are potent, selective agonists of melanocortin 1 receptor (MC1R). Provided herein are pharmaceutical compositions including Formula I peptide agonists of MC1R and methods of treating skin diseases and disorders that include administering to an individual in need thereof a therapeutic amount of a Formula I peptide. The peptides, pharmaceutical compositions, and methods described herein are useful in the treatment of diseases and disorders that benefit from agonism of MCIR, including melanoma, basal cell carcinoma, squamous cell carcinoma, porphyria, polymorphous light eruption, vitiligo, and solar urticaria.

Short tri- and tetrapeptides according to the following Formula I Ar(CH2).sub.mX.sup.1—X.sup.2—CO—X.sup.3—X.sup.4—X.sup.5-(Trp).sub.n-NX.sup.6R are potent, selective agonists of melanocortin 1 receptor (MC1R). Provided herein are pharmaceutical compositions including Formula I peptide agonists of MC1R and methods of treating skin diseases and disorders that include administering to an individual in need thereof a therapeutic amount of a Formula I peptide. The peptides, pharmaceutical compositions, and methods described herein are useful in the treatment of diseases and disorders that benefit from agonism of MCIR, including melanoma, basal cell carcinoma, squamous cell carcinoma, porphyria, polymorphous light eruption, vitiligo, and solar urticaria.

The invention relates generally to new compounds of formula (I), wherein R.sub.1, R′.sub.1, R.sub.2, R′.sub.2, R.sub.3, R′.sub.3, R.sub.4 R′.sub.4, R.sub.5, R′.sub.5, R.sub.6, R.sub.7 are independently of one another and denote hydrogen, hydroxyl, C.sub.1 to C.sub.6-alkyl group or R.sub.6 and R.sub.7 form together a C5-C6 ring system, and wherein n=0, 1, 2, 3, or 4. Moreover, the invention relates to the use of one or more compounds of formula (I) in cosmetic or pharmaceutical compositions, which are preferably dermatological compositions and are preferably used topically. ##STR00001##

The invention relates generally to new compounds of formula (I), wherein R.sub.1, R′.sub.1, R.sub.2, R′.sub.2, R.sub.3, R′.sub.3, R.sub.4 R′.sub.4, R.sub.5, R′.sub.5, R.sub.6, R.sub.7 are independently of one another and denote hydrogen, hydroxyl, C.sub.1 to C.sub.6-alkyl group or R.sub.6 and R.sub.7 form together a C5-C6 ring system, and wherein n=0, 1, 2, 3, or 4. Moreover, the invention relates to the use of one or more compounds of formula (I) in cosmetic or pharmaceutical compositions, which are preferably dermatological compositions and are preferably used topically. ##STR00001##

The present invention relates to the use of phenyl ketone derivatives of the formula I for use as self-tanning substance or for increasing melanin synthesis, improving melanin transport and/or improving the distribution of melanin in suprabasal layers, and to preparations comprising these phenyl ketone derivatives.